Nortriptyline Alternatives Compared
| Nortriptyline | Topiramate | Topamax (topiramate) |
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| Nortriptyline | Topiramate | Topamax (topiramate) |
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Prescription only
Nortriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. It may be used off-label to treat other conditions, such as... View more |
Prescription only
Topiramate may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraines. Drowsiness is a... View more |
Prescription only
Topamax may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraine. Drowsiness is a... View more |
Related suggestions Migraine Prevention (Migraine Prophylaxis)
Popular comparisons
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| More about Nortriptyline | More about Topiramate | More about Topamax (topiramate) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Nortriptyline has an average rating of 7.3 out of 10 from a total of 566 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 19% reported a negative effect. |
Topiramate has an average rating of 6.3 out of 10 from a total of 1330 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 28% reported a negative effect. |
Topamax has an average rating of 6.1 out of 10 from a total of 644 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 30% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Nortriptyline prices |
View all Topiramate prices |
View all Topamax prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Pamelor | Eprontia, Qudexy XR, Topamax, Trokendi XR | Other topiramate brands include: Eprontia, Qudexy XR, Trokendi XR | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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31 hours |
56 hours |
56 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 699 drugs are known to interact with Nortriptyline:
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A total of 291 drugs are known to interact with Topiramate:
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A total of 291 drugs are known to interact with Topamax:
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| First Approval Date | ||||||||||||||||||||||||||
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November 06, 1964 |
December 24, 1996 |
December 24, 1996 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.