Comparing Naproxen vs Oxycodone
| Naproxen | Oxycodone |
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| Naproxen | Oxycodone |
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Prescription and OTC
Naproxen is effective for the short-term relief of pain and inflammation associated with arthritis, gout, menstruation, and tendonitis; however, like other NSAIDs, it has the potential to adversely... View more |
Prescription only
Oxycodone is a semisynthetic opioid medication with potent pain-relieving properties that may be used to relieve severe pain that is unresponsive to less potent pain-relieving medicines (analgesics)... View more |
Related suggestions Chronic Pain
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| More about Naproxen | More about Oxycodone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Naproxen has an average rating of 6.8 out of 10 from a total of 683 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 25% reported a negative effect. |
Oxycodone has an average rating of 6.9 out of 10 from a total of 1143 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 25% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Naproxen side effects |
View all Oxycodone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Naproxen prices |
View all Oxycodone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aflaxen, Aleve, Aleve Back and Muscle Pain, All Day Pain Relief, All Day Relief, Anaprox-DS, Comfort Pac with Naproxen, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan, Naprosyn, Naproxen Sodium DS, Pamprin All Day Relief View more | Dazidox, Endocodone, ETH-Oxydose, Oxaydo, OxyContin, Oxydose, Oxyfast, Roxicodone, RoxyBond, Xtampza ER View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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18 hours |
5.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 451 drugs are known to interact with Naproxen:
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A total of 615 drugs are known to interact with Oxycodone:
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| First Approval Date | |||||||||||||||||
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March 11, 1976 |
October 26, 1998 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.