Mexiletine Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Mexiletine	Amiodarone	Propranolol	Enter another drug to compare

Mexiletine

Amiodarone

Propranolol

Prescription only

Prescribed for Ventricular Tachycardia, Myotonia Congenita, Diabetic Peripheral Neuropathy, Arrhythmia. Mexiletine may also be used for purposes not listed in this medication guide.

Prescription only

Amiodarone should ONLY be used in the treatment of life-threatening ventricular arrhythmias that have not responded to other treatments. Amiodarone does not appear to increase life expectancy and can... View more

Prescription only

Propranolol is mainly used for blood pressure and angina control; however, it also has a role in migraine prevention and the treatment of essential tremor. Propranolol may cause vivid dreams and is... View more

More about Mexiletine

More about Amiodarone

More about Propranolol

Ratings & Reviews

Mexiletine has an average rating of 6.1 out of 10 from a total of 12 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 33% reported a negative effect.

Amiodarone has an average rating of 4.9 out of 10 from a total of 95 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 48% reported a negative effect.

Propranolol has an average rating of 8.2 out of 10 from a total of 1377 ratings on Drugs.com. 77% of reviewers reported a positive effect, while 12% reported a negative effect.

View all 12 reviews

View all 95 reviews

View all 1377 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Mexiletine side effects

Tiredness (14.7%)
Dizziness (10.5%)
Insomnia (10.5%)
Shortness of breath (10.5%)
Weakness (6.3%)
Constipation (5.3%)
Cough (5.3%)

View all Amiodarone side effects

Tremors (10.5%)
Anxiety (6.8%)
Tiredness (6.6%)
Increased heart rate (6.5%)
Dizziness (5.2%)
Sweating (4.9%)
Headaches (4.1%)

View all Propranolol side effects

Drug Class

Group I antiarrhythmics

Group III antiarrhythmics

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	30 each
Strength	150 mg
Per unit^*	$1.09
Cost^*	$32.82

View all Mexiletine prices

Quantity	100 each
Strength	200 mg
Per unit^*	$0.28 - $0.52
Cost^*	$27.86 - $52.44

View all Amiodarone prices

Quantity	50 each
Strength	20 mg
Per unit^*	$0.35
Cost^*	$17.39

View all Propranolol prices

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Dosage Forms

Oral capsule

Intravenous solution
Oral tablet

Intravenous solution
Oral capsule, extended release
Oral solution
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

14 hours

240 hours

6.4 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 152 drugs are known to interact with Mexiletine:

20 major drug interactions (133 brand and generic names)
120 moderate drug interactions (499 brand and generic names)
12 minor drug interactions (66 brand and generic names)

A total of 744 drugs are known to interact with Amiodarone:

312 major drug interactions (1069 brand and generic names)
395 moderate drug interactions (1500 brand and generic names)
37 minor drug interactions (189 brand and generic names)

A total of 589 drugs are known to interact with Propranolol:

47 major drug interactions (215 brand and generic names)
492 moderate drug interactions (3283 brand and generic names)
50 minor drug interactions (611 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Amiodarone may be taken with or without food but should be taken at the same way each time. You... View more

Food can enhance the levels of propranolol in your body. You shoud take propranolol at the same... View more

Disease Interactions

First Approval Date

December 30, 1985

December 24, 1985

November 13, 1967

WADA Class View classifications

N/A

P1 - Beta-Blockers

More Information

Patient Resources

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Mexiletine Alternatives Compared

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