Comparing Metaxalone vs Tizanidine
| Metaxalone | Tizanidine |
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| Metaxalone | Tizanidine |
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Prescription only
Metaxalone is a muscle relaxant that appears to exert its effects through sedation. Taking metaxalone with food can increase its absorption and enhance its effects (such as sedation). Seniors may be... View more |
Prescription only
Tizanidine may be used to reduce muscle spasms but common side effects include sleepiness, a drop in blood pressure, and a dry mouth. The dosage of tizanidine should be tailored to each person and... View more |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
Popular comparisons
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| More about Metaxalone | More about Tizanidine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Metaxalone has an average rating of 7.0 out of 10 from a total of 126 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 21% reported a negative effect. |
Tizanidine has an average rating of 6.2 out of 10 from a total of 380 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Metaxalone side effects |
View all Tizanidine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Metaxalone prices |
View all Tizanidine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Metaxal, Metaxall, Skelaxin | Ontralfy, Zanaflex | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3 hours |
2.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 317 drugs are known to interact with Metaxalone:
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A total of 638 drugs are known to interact with Tizanidine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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August 13, 1962 |
November 27, 1996 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.