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Malarone Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Malarone (atovaquone / proguanil) Doxycycline Atovaquone / proguanil
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Malarone (atovaquone / proguanil) Doxycycline Atovaquone / proguanil
Prescription only

Prescribed for Malaria Prevention, Malaria. Malarone may also be used for purposes not listed in this medication guide.

Prescription only

Doxycycline is an effective antibiotic that treats a wide range of infections. However, it is not usually recommended for children aged less than eight or pregnant women in the last half of their... View more

Prescription only

Prescribed for Malaria Prevention, Malaria. Atovaquone / proguanil may also be used for purposes not listed in this medication guide.

More about Malarone (atovaquone / proguanil) More about Doxycycline More about Atovaquone / proguanil
Ratings & Reviews

Malarone has an average rating of 5.5 out of 10 from a total of 45 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 40% reported a negative effect.

Doxycycline has an average rating of 6.4 out of 10 from a total of 1635 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 27% reported a negative effect.

Atovaquone / proguanil has an average rating of 5.2 out of 10 from a total of 50 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 44% reported a negative effect.

View all 45 reviews

View all 1635 reviews

View all 50 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Malarone side effects

View all Doxycycline side effects

View all Atovaquone / proguanil side effects
Drug Class
Generic Availability

Lower cost generic approved

Lower cost generic

Lower cost generic
Pricing and Coupons * Prices are without insurance
Quantity 24 tablet
Strength 250 mg-100 mg
Per unit* $7.75
Cost* $185.93

View all Malarone prices

Quantity 2 tablet
Strength hyclate 100 mg
Per unit* $6.62
Cost* $13.23

View all Doxycycline prices

Quantity 24 each
Strength 250 mg-100 mg
Per unit* $5.42 - $5.43
Cost* $130.07 - $130.35

View all Atovaquone / proguanil prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Dosage Forms
  • Oral tablet
  • Injectable powder for injection
  • Oral capsule
  • Oral delayed release capsule
  • Oral delayed release tablet
  • Oral powder for reconstitution
  • Oral tablet
  • Oral tablet
Brand Names
Other atovaquone / proguanil brands include: Malarone Pediatric Acticlate, Adoxa, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Doryx MPC, Doxy 100, Doxy 200, Doxy-Caps, Doxy-D, LymePak, Mondoxyne NL, Monodox, Morgidox, Okebo, Oracea, Oraxyl, Targadox, Uracil, Vibramycin View more Malarone, Malarone Pediatric
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

60.5 hours

23 hours

60.5 hours
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
D
Category D Positive evidence of risk

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
Drug Interactions

A total of 122 drugs are known to interact with Malarone:

  • 13 major drug interactions (27 brand and generic names)
  • 102 moderate drug interactions (578 brand and generic names)
  • 7 minor drug interactions (21 brand and generic names)

A total of 223 drugs are known to interact with Doxycycline:

  • 22 major drug interactions (60 brand and generic names)
  • 196 moderate drug interactions (2214 brand and generic names)
  • 5 minor drug interactions (21 brand and generic names)

A total of 122 drugs are known to interact with Atovaquone / proguanil:

  • 13 major drug interactions (27 brand and generic names)
  • 102 moderate drug interactions (578 brand and generic names)
  • 7 minor drug interactions (21 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
  • Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone... View more
Disease Interactions
First Approval Date

July 14, 2000

December 05, 1967

July 14, 2000
WADA Class View classifications

N/A

N/A

N/A
More Information
Patient Resources
Professional Resources
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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