Comparing Malarone vs Plaquenil
| Malarone (atovaquone / proguanil) | Plaquenil (hydroxychloroquine) |
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| Malarone (atovaquone / proguanil) | Plaquenil (hydroxychloroquine) |
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Prescription only
Prescribed for Malaria Prevention, Malaria. Malarone may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Rheumatoid Arthritis, Lupus, Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention. Plaquenil may also be used for purposes not listed in this medication guide. |
Related suggestions Malaria Prevention (Malaria Prophylaxis)
Popular comparisons
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| More about Malarone (atovaquone / proguanil) | More about Plaquenil (hydroxychloroquine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Malarone has an average rating of 5.5 out of 10 from a total of 45 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 40% reported a negative effect. |
Plaquenil has an average rating of 6.4 out of 10 from a total of 158 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 28% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Malarone side effects |
View all Plaquenil side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Malarone prices |
View all Plaquenil prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other atovaquone / proguanil brands include: Malarone Pediatric | Other hydroxychloroquine brands include: Sovuna | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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60.5 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 122 drugs are known to interact with Malarone:
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A total of 580 drugs are known to interact with Plaquenil:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 14, 2000 |
April 18, 1955 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.