Lunesta Alternatives Compared
| Lunesta (eszopiclone) | Trazodone | Zolpidem |
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| Lunesta (eszopiclone) | Trazodone | Zolpidem |
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Prescription only
Prescribed for Insomnia. Lunesta may also be used for purposes not listed in this medication guide. |
Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Prescription only
Zolpidem induces sleep; however, longer-acting formulations may impair physical and mental capabilities the next day. May induce complex or dangerous sleep-related behaviors like "sleep-driving"... View more |
Related suggestions |
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| More about Lunesta (eszopiclone) | More about Trazodone | More about Zolpidem | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Lunesta has an average rating of 5.9 out of 10 from a total of 342 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 35% reported a negative effect. |
Trazodone has an average rating of 6.3 out of 10 from a total of 1432 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
Zolpidem has an average rating of 6.9 out of 10 from a total of 1056 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Lunesta side effects |
View all Trazodone side effects |
View all Zolpidem side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Lunesta prices |
View all Trazodone prices |
View all Zolpidem prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Raldesy | Ambien, Ambien CR, Edluar, Zolpimist | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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6 hours |
7.5 hours |
2.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 384 drugs are known to interact with Lunesta:
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A total of 672 drugs are known to interact with Trazodone:
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A total of 480 drugs are known to interact with Zolpidem:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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December 15, 2004 |
December 24, 1981 |
December 16, 1992 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.