Comparing Lisdexamfetamine vs Modafinil
| Lisdexamfetamine | Modafinil |
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| Lisdexamfetamine | Modafinil |
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Prescription only
Lisdexamfetamine is a stimulant that may be used for the treatment of ADHD and BED; however, its use is limited by its risk of dependence, withdrawal syndrome, and potential for serious cardiac... View more |
Prescription only
Prescribed for Chronic Fatigue Syndrome, ADHD, Fatigue, Depression, Shift Work Sleep Disorder, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Idiopathic Hypersomnia. Modafinil may also be... View more |
Related suggestions Depression
ADHD (Attention Deficit Hyperactivity Disorder)
Chronic Fatigue Syndrome
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| More about Lisdexamfetamine | More about Modafinil | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Lisdexamfetamine has an average rating of 7.5 out of 10 from a total of 1088 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 15% reported a negative effect. |
Modafinil has an average rating of 7.2 out of 10 from a total of 535 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Lisdexamfetamine side effects |
View all Modafinil side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Lisdexamfetamine prices |
View all Modafinil prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Vyvanse | Provigil | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1 hour |
15 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 393 drugs are known to interact with Lisdexamfetamine:
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A total of 519 drugs are known to interact with Modafinil:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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February 23, 2007 |
December 24, 1998 |
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| WADA Class View classifications | |||||||||||||||||
| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.