Lisdexamfetamine Alternatives Compared
| Lisdexamfetamine | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Adderall (amphetamine / dextroamphetamine) |
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| Lisdexamfetamine | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Adderall (amphetamine / dextroamphetamine) |
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Prescription only
Lisdexamfetamine is a stimulant that may be used for the treatment of ADHD and BED; however, its use is limited by its risk of dependence, withdrawal syndrome, and potential for serious cardiac... View more |
Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
Prescription only
Adderall is a combination of four different amphetamine salts and may be used to improve attention, focus, or reduce impulsive behaviors in children over the age of 3 and adults with ADHD. It can... View more |
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| More about Lisdexamfetamine | More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | More about Adderall (amphetamine / dextroamphetamine) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Lisdexamfetamine has an average rating of 7.5 out of 10 from a total of 1088 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 15% reported a negative effect. |
Xywav has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 13% reported a negative effect. |
Adderall has an average rating of 7.2 out of 10 from a total of 505 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Lisdexamfetamine side effects |
View all Xywav side effects |
View all Adderall side effects |
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| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Lisdexamfetamine prices |
View all Xywav prices |
View all Adderall prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Vyvanse |
N/A |
Other amphetamine / dextroamphetamine brands include: Adderall XR, Mydayis | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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1 hour |
0.66 hours |
14 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 393 drugs are known to interact with Lisdexamfetamine:
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A total of 346 drugs are known to interact with Xywav:
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A total of 220 drugs are known to interact with Adderall:
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| First Approval Date | ||||||||||||||||||||||||||
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February 23, 2007 |
July 21, 2020 |
January 19, 1960 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.