Linagliptin / metformin Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Linagliptin / metformin	Ozempic (semaglutide)	Mounjaro (tirzepatide)	Enter another drug to compare

Linagliptin / metformin

Ozempic (semaglutide)

Mounjaro (tirzepatide)

Prescription only

Prescribed for Type 2 Diabetes. Linagliptin / metformin may also be used for purposes not listed in this medication guide.

Prescription only

Ozempic lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is... View more

Prescription only

Prescribed for Weight Loss (Obesity/Overweight), Type 2 Diabetes. Mounjaro may also be used for purposes not listed in this medication guide.

More about Linagliptin / metformin

More about Ozempic (semaglutide)

More about Mounjaro (tirzepatide)

Ratings & Reviews

Linagliptin / metformin has an average rating of 6.2 out of 10 from a total of 17 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 33% reported a negative effect.

Ozempic has an average rating of 6.7 out of 10 from a total of 1492 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 22% reported a negative effect.

Mounjaro has an average rating of 8.6 out of 10 from a total of 1243 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 6% reported a negative effect.

View all 17 reviews

View all 1492 reviews

View all 1243 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Linagliptin / metformin side effects

Nausea (31.5%)
Diarrhea (15.5%)
Constipation (14.5%)
Vomiting (11.5%)
Burping (8.2%)
Headaches (7.6%)
Upset stomach (7.2%)

View all Ozempic side effects

Nausea (15.8%)
Constipation (10.4%)
Diarrhea (7.6%)
Loss of appetite (4.3%)
Upset stomach (4.3%)
Vomiting (4.3%)
Burping (4.1%)

View all Mounjaro side effects

Drug Class

Antidiabetic combinations

GLP-1 Agonists (Incretin Mimetics)

GLP-1 Agonists (Incretin Mimetics)

Generic Availability

N/A

No lower cost generic approved

Pricing and Coupons * Prices are without insurance

We could not find an exact match for this medicine. Try searching the Price Guide directly.

Quantity	3 mL
Strength	2 mg/3 mL (0.25 mg or 0.5 mg dose)
Per unit^*	$350.24
Cost^*	$1,050.73

View all Ozempic prices

Quantity	2 mL
Strength	2.5 mg/0.5 mL
Per unit^*	$568.27
Cost^*	$1,136.53

View all Mounjaro prices

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Dosage Forms

N/A

Subcutaneous solution

Subcutaneous solution

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

12 hours

168 hours

120 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Drug Interactions

A total of 449 drugs are known to interact with Linagliptin / metformin:

25 major drug interactions (131 brand and generic names)
415 moderate drug interactions (1951 brand and generic names)
9 minor drug interactions (35 brand and generic names)

A total of 273 drugs are known to interact with Ozempic:

15 major drug interactions (34 brand and generic names)
257 moderate drug interactions (1448 brand and generic names)
1 minor drug interactions (10 brand and generic names)

A total of 414 drugs are known to interact with Mounjaro:

15 major drug interactions (34 brand and generic names)
398 moderate drug interactions (2268 brand and generic names)
1 minor drug interactions (10 brand and generic names)

Alcohol/Food/Lifestyle Interactions

MetFORMIN should be taken with meals, and excessive alcohol intake (either short-term binge... View more

Food may affect the absorption of semaglutide when taken orally. It is recommended that oral... View more
Talk to your doctor before using alcohol together with semaglutide. Alcohol may affect blood... View more

Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases... View more
Talk to your doctor before using alcohol together with tirzepatide. Alcohol may affect blood... View more

Disease Interactions

First Approval Date

January 30, 2012

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Ozempic uses

Mounjaro uses

Professional Resources

N/A

Prescribing information

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Linagliptin / metformin Alternatives Compared

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