Comparing Hydrochlorothiazide vs Nifedipine
| Hydrochlorothiazide | Nifedipine |
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| Hydrochlorothiazide | Nifedipine |
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Prescription only
Hydrochlorothiazide (HCTZ) may be used to relieve edema (fluid retention) and to lower high blood pressure. A headache, dizziness on standing, dehydration, skin reactions, and depletion of... View more |
Prescription only
Nifedipine is used in the treatment of vasospastic angina and occasionally for chronic unstable angina as an add-on to other treatments. It should not be used to rapidly drop blood pressure as this... View more |
Related suggestions High Blood Pressure (Hypertension)
Popular comparisons
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| More about Hydrochlorothiazide | More about Nifedipine | ||||||||
| Ratings & Reviews | |||||||||
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Hydrochlorothiazide has an average rating of 5.2 out of 10 from a total of 185 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 38% reported a negative effect. |
Nifedipine has an average rating of 4.9 out of 10 from a total of 161 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 44% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Hydrochlorothiazide side effects |
View all Nifedipine side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Hydrochlorothiazide prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Aquazide H, Carozide, Diaqua, Esidrix, Ezide, Hydro Par, Inzirqo, Microzide | Afeditab CR, Procardia, Procardia XL | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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12 hours |
5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 472 drugs are known to interact with Hydrochlorothiazide:
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A total of 623 drugs are known to interact with Nifedipine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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February 12, 1959 |
December 31, 1981 |
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| WADA Class View classifications | |||||||||
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N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.