Comparing Guaifenesin vs Phenylephrine
| Guaifenesin | Phenylephrine |
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| Guaifenesin | Phenylephrine |
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Prescription and OTC
Guaifenesin is an expectorant that helps thin and remove mucus from the airways. It is generally well tolerated. Prescribed for Bronchitis, Bronchiectasis, Cough, Fibromyalgia. Guaifenesin may also... View more |
Prescription and OTC
Phenylephrine relieves congestion of the nasal passages and is found in many cold and flu remedies. There is some controversy over whether it works at the dosages usually found in over-the-counter... View more |
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| More about Guaifenesin | More about Phenylephrine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Guaifenesin has an average rating of 7.1 out of 10 from a total of 305 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 24% reported a negative effect. |
Phenylephrine has an average rating of 6.2 out of 10 from a total of 23 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 39% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Guaifenesin side effects |
View all Phenylephrine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Guaifenesin prices |
View all Phenylephrine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Air Power, Allfen Jr, Altarussin, Altorant, Amibid LA, Anti-Tuss, Aquamist, Balminil Expectorant, Beechams Veno's Expectorant, Beechams Veno's for Kids Chesty Cough, Benadryl Chesty Forte, Benylin E, Bidex-400, Breonesin, Bronchoril, Buckley's Chest Congestion, Calmylin Expectorant, Diabetic Expectorant, Diabetic Tuss, Diabetic Tussin Chest Congestion, Diabetic Tussin Mucus Relief, Dristan Chesty Cough, Dristan Chesty Cough Guaiphenesin, Drituss G, Duratuss G, Family Meltus Chesty Coughs, Fenesin, Fenesin IR, Fenex-LA, G Bid, Ganidin NR, Genatuss, GG 200 NR, GG-Cen, Giltuss Children's EX Expectorant, Giltuss EX Expectorant, Glytuss, Gua-SR, Guaiatussin, Guaibid-LA, Guaifen NR, Guaifenesin LA, Guaifenex G, Guaifenex LA, Guiacough, Guiadrine G-1200, Guiatuss, Help I Have Chest Congestion, Hill's Balsam Chesty Cough, Humavent LA, Humibid, Humibid E, Humibid Pediatric, Humigen LA, Hytuss, Junior Meltus Chesty Coughs with Catarrh, Junior Meltus Colour and Sugar Free Expectorant, Lemsip Cough Chesty, Mucaplex, Mucinex, Mucinex Children's Chest Congestion, Mucinex for Kids, Mucinex Maximum Strength, Mucobid-LA, Organ-1 NR, Refenesen Chest Congestion Relief, Robafen, Robitussin Mucus + Chest Congestion, Rompe Pecho EX, Scot-Tussin Expectorant, Siltuss DAS, Siltussin DAS, Siltussin DAS-NA, TabTussin 400, Tussin Expectorant, Tussin Mucus + Chest Congestion, Xpect View more | AH-Chew D, Biorphen, Congest Aid II, Contac-D, Despec-SF, Dimetapp Toddler's Drops Decongestant, Gilchew IR, Little Colds Decongestant, Nasal Decongestant PE, Nasop, Nasop12, Neo-Synephrine, Ricobid-D, Sudafed PE Children's Nasal Decongestant, Sudafed PE Congestion, Sudogest PE, Suphedrine PE, Vazculep View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1 hour |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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No known drug interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
A total of 201 drugs are known to interact with Phenylephrine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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July 12, 2002 |
December 20, 2012 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.