Glimepiride / pioglitazone Alternatives Compared
| Glimepiride / pioglitazone | Semaglutide | Tirzepatide |
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| Glimepiride / pioglitazone | Semaglutide | Tirzepatide |
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Prescription only
Prescribed for Diabetes - Type 2. Glimepiride / pioglitazone may also be used for purposes not listed in this medication guide. |
Prescription only
Semaglutide lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is taken... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Diabetes - Type 2. Tirzepatide may also be used for purposes not listed in this medication guide. |
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| More about Glimepiride / pioglitazone | More about Semaglutide | More about Tirzepatide | ||||||||
| Ratings & Reviews | ||||||||||
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Glimepiride / pioglitazone has an average rating of 1.0 out of 10 from a total of 2 ratings on Drugs.com. 0% of reviewers reported a positive effect, while 100% reported a negative effect. |
Semaglutide has an average rating of 6.9 out of 10 from a total of 2356 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 22% reported a negative effect. |
Tirzepatide has an average rating of 8.7 out of 10 from a total of 1453 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 5% reported a negative effect. |
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| Drug Class | ||||||||||
| Side Effects | ||||||||||
| Generic Availability | ||||||||||
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Lower cost generic |
N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||
View all Glimepiride / pioglitazone prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms Available | ||||||||||
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N/A |
N/A |
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| Brand Names | ||||||||||
| Duetact | Ozempic, Rybelsus, Wegovy | Mounjaro, Zepbound | ||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||
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16.35 hours |
168 hours |
120 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||
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A total of 557 drugs are known to interact with Glimepiride / pioglitazone:
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A total of 266 drugs are known to interact with Semaglutide:
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A total of 411 drugs are known to interact with Tirzepatide:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||
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| Disease Interactions | ||||||||||
| First Approval Date | ||||||||||
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July 28, 2006 |
December 05, 2017 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||
| Patient resources | ||||||||||
| Professional Resources | ||||||||||
| Related Treatment Guide | ||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.