Comparing Fluoxetine vs Venlafaxine
| Fluoxetine | Venlafaxine |
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| Fluoxetine | Venlafaxine |
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Prescription only
Fluoxetine may be used for the treatment of certain types of mood disorders and also some eating disorders. It is more likely to cause insomnia than drowsiness. Taking fluoxetine with other... View more |
Prescription only
Venlafaxine is an antidepressant that may also be used for mood disorders and off-label for some other conditions such as hot flashes. It may cause a discontinuation syndrome if abruptly stopped... View more |
Related suggestions Depression
Major Depressive Disorder
Anxiety and Stress
Panic Disorder
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| More about Fluoxetine | More about Venlafaxine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Fluoxetine has an average rating of 7.4 out of 10 from a total of 2208 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 18% reported a negative effect. |
Venlafaxine has an average rating of 6.5 out of 10 from a total of 2771 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 28% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: fluoxetine side effects in more detail. |
See also: venlafaxine side effects in more detail. |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all fluoxetine prices |
View all venlafaxine prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Prozac | Effexor, Effexor XR | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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210 hours |
4 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 677 drugs are known to interact with fluoxetine:
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A total of 695 drugs are known to interact with venlafaxine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 29, 1987 |
December 28, 1993 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.