Comparing Excedrin vs Naproxen
| Excedrin (acetaminophen / aspirin / caffeine) | Naproxen |
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| Excedrin (acetaminophen / aspirin / caffeine) | Naproxen |
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Over-the-counter
Prescribed for Migraine, Osteoarthritis, Pain/Fever. Excedrin may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Naproxen is effective for the short-term relief of pain and inflammation associated with arthritis, gout, menstruation, and tendonitis; however, like other NSAIDs, it has the potential to adversely... View more |
Related suggestions Osteoarthritis
Pain/Fever
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| More about Excedrin (acetaminophen / aspirin / caffeine) | More about Naproxen | ||||||||
| Ratings & Reviews | |||||||||
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Excedrin has an average rating of 6.8 out of 10 from a total of 39 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 33% reported a negative effect. |
Naproxen has an average rating of 6.8 out of 10 from a total of 683 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 25% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
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View all Excedrin side effects |
View all Naproxen side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Naproxen prices |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other acetaminophen / aspirin / caffeine brands include: Anacin Advanced Headache Formula, Arthriten, Arthriten Inflammatory Pain Formula, Backaid Inflammatory Pain Formula, Bayer Migraine Formula, ConRx Pain Reliever, CVS Extra Strength Headache Relief, Excedrin Extra Strength, Excedrin Migraine, Extra Pain Relief, Genace, Goody's Extra Strength, Goody's Extra-Strength Headache Powders, Goody's Headache Powders, Medique Pain-Off, Migraine Formula, Migraine Relief, PainAid Extra-Strength Formula, Pamprin Max Menstrual Pain Relief, Vanquish View more | Aflaxen, Aleve, Aleve Back and Muscle Pain, All Day Pain Relief, All Day Relief, Anaprox-DS, Comfort Pac with Naproxen, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan, Naprosyn, Naproxen Sodium DS, Pamprin All Day Relief View more | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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10 hours |
18 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 576 drugs are known to interact with Excedrin:
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A total of 451 drugs are known to interact with Naproxen:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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N/A |
March 11, 1976 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.