Comparing Excedrin vs Ibuprofen
| Excedrin | Ibuprofen |
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| Excedrin (acetaminophen / aspirin / caffeine) | Ibuprofen |
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Over-the-counter
Prescribed for Migraine, Pain/Fever, Osteoarthritis. Excedrin may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Ibuprofen is effective for the short-term relief of minor aches and pains and also reduces inflammation. The risk of stomach-related side effects is about half that seen with aspirin although the... View more |
Related suggestions Migraine
Pain/Fever
Popular comparisons
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| More about Excedrin (acetaminophen / aspirin / caffeine) | More about Ibuprofen | ||||||||
| Ratings & Reviews | |||||||||
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Excedrin has an average rating of 7.1 out of 10 from a total of 39 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 31% reported a negative effect. |
Ibuprofen has an average rating of 7.4 out of 10 from a total of 234 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Drug Class | |||||||||
| Side Effects | |||||||||
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See also: Excedrin side effects in more detail. |
See also: Ibuprofen side effects in more detail. |
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| Generic Availability | |||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Ibuprofen prices |
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| Dosage Forms Available | |||||||||
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| Brand Names | |||||||||
| Other acetaminophen / aspirin / caffeine brands include: Anacin Advanced Headache Formula, Arthriten, Arthriten Inflammatory Pain Formula, Backaid Inflammatory Pain Formula, Bayer Migraine Formula, ConRx Pain Reliever, CVS Extra Strength Headache Relief, Excedrin Extra Strength, Excedrin Migraine, Extra Pain Relief, Genace, Goody's Extra Strength, Goody's Extra-Strength Headache Powders, Goody's Headache Powders, Medique Pain-Off, Migraine Formula, Migraine Relief, PainAid Extra-Strength Formula, Pamprin Max Menstrual Pain Relief, Vanquish View more | A-G Profen, Actiprofen, Addaprin, Advil, Advil Children's, Advil Film-Coated, Advil Infant's Concentrated Drops, Advil Junior Strength, Advil Liqui-Gels, Advil Migraine, Caldolor, Cap-Profen, Children's ElixSure IB, Children's Motrin, Childrens Ibuprofen Berry, Genpril, Help I Have An Aching Body, IBU-200, Midol IB, Midol Maximum Strength Cramp Formula, Motrin, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Motrin Pediatric, NeoProfen, Nuprin, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Proprinal View more | ||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
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10 hours |
4 hours |
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| CSA Schedule ** View glossary of terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 531 drugs are known to interact with Excedrin:
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A total of 397 drugs are known to interact with Ibuprofen:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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N/A |
September 19, 1974 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.