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Ibuprofen and Stomach Pain: What Users Say

Brand names: Advil, Motrin, Motrin IB, Advil Liqui-Gels, Motrin Childrens, Children's Motrin, Proprinal, Advil Migraine, Childrens Ibuprofen Berry, Caldolor, IBU-200, Midol IB, A-G Profen, Advil Children's, Nuprin, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Infant Drops, NeoProfen, Advil Film-Coated, Genpril, Advil Junior Strength Midol Maximum Strength Cramp Formula Actiprofen Motrin Migraine Pain Addaprin PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer Motrin Junior Strength Help I Have An Aching Body Children's ElixSure IB Advil Infant's Concentrated Drops Cap-Profen Motrin Pediatric …show all brand names

Stomach pain: mentioned by 6 users (2.5%)

Based on user experiences from 240 Ibuprofen reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

upset stomach 4.6%
nausea 4.2%
diarrhea 2.5%
stomach pain 2.5%
vomiting 2.5%
allergic reaction 1.3%
headaches 1.3%
heartburn 1.3%
swelling 1.3%

Reviews for Ibuprofen

Commonly mentioned side effects
  • Mou...
  • Taken for 10 years or more
  • November 13, 2013

For Osteoarthritis "Been taking ibuprofen 800 mg 3x a day, and always with food. A PA urged me to go off of it last Mon (now Wed) and replace it with tramadol; said he didn't know anyone who didn't get stomach ulcers or have kidney problems when on ibuprofen for an extended period. Each day pain grew worse until today I could hardly get out of bed as the pain was excruciating. Cooked breakfast in a hurry, switched back to ibuprofen, and now pain-free by noon."

9 / 10
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61 Report
  • efa...
  • Taken for 10 years or more
  • May 1, 2014

For Pain "Ibuprofen was my default pain relief early in my experience with ankylosing spondylitis. It reduced inflammation and made the pain, discomfort, and stiffness more manageable. I did experience some side effects (constipation, followed by diarrhea due to the blockage, stomach pains, etc.), but the pain management helped to make it bearable. I managed on it for over 10 years before my fusion made the pain worse."

6 / 10
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18 Report
  • Suz...
  • October 20, 2019

For Pain "My lower spine was injured in a car accident. The L-3 was crushed, resulting in paralysis in one leg. I also developed Crohn’s disease. After using ibuprofen for months, I developed symptoms of stomach ulcers, so I stopped taking it, and within a day, the feelings of being either hot or cold completely disappeared. I can now sleep through the night without waking up hot and sweaty. I would also experience episodes of feeling extremely cold, oftentimes soon after feeling extremely hot. I would put on extra clothing, go to bed with extra blankets until I finally warmed up. These two symptoms went on for months but have now completely stopped shortly after stopping the ibuprofen."

5 / 10
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7 Report

Frequently asked questions

  • pse...
  • Taken for less than 1 month
  • October 16, 2016

Ibuprofen for Headache "Advil is my pain reliever of choice, and I take it occasionally to relieve severe headaches; however, it is not without its (many) faults. For starters, it often takes as long as 2 hours to start acting. Also, it is VERY hard on my stomach—taking even the smallest recommended dose makes me feel queasy and nauseous. I actually prefer the children's Advil, as it has a similar pain-relieving effect without as much stomach pain. Overall, Advil is a worthwhile pain medication, but I would recommend using it sparingly."

7 / 10
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9 Report
  • Bec...
  • Taken for less than 1 month
  • December 17, 2021

For Pain "I was told to take ibuprofen every day for neck pain. Well, after 5 days, I got the most painful stomach pains and vomiting and got taken to the hospital, where they said don’t take it anymore as it can strip your stomach lining! I had developed acute gastritis from it and was extremely sick and uncomfortable for 5 days and put on a proton pump inhibitor to heal my stomach lining. I will never take an NSAID again if I can help it, what a nightmare!"

2 / 10
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4 Report
  • Mur...
  • September 26, 2009

For Pain "I have used this drug for 20 years. Cannot take other NSAIDs because they cause stomach pain. But for some reason, ibuprofen I can take with no problem at all. And it works on all my joint pain."

10 / 10
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16 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.