Copiktra Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Copiktra (duvelisib)	Ibrutinib	Acalabrutinib	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Copiktra (duvelisib)	Ibrutinib	Acalabrutinib	Enter another drug to compare
Prescription only Prescribed for Chronic Lymphocytic Leukemia. Copiktra may also be used for purposes not listed in this medication guide.	Prescription only Ibrutinib is an oral tablet that may be taken once daily to treat certain types of cancers in adults or to treat chronic Graft Versus Host disease in adults and children older than 1 year. It works... View more	Prescription only Prescribed for Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma. Acalabrutinib may also be used for purposes not listed in this medication guide.	Related suggestions Chronic Lymphocytic Leukemia Imbruvica Rituxan Calquence Gazyva Obinutuzumab Brukinsa
More about Copiktra (duvelisib)	More about Ibrutinib	More about Acalabrutinib
Ratings & Reviews
Be the first to share your experience with this drug.	Ibrutinib has an average rating of 6.6 out of 10 from a total of 78 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 29% reported a negative effect.	Acalabrutinib has an average rating of 8.8 out of 10 from a total of 32 ratings on Drugs.com. 87% of reviewers reported a positive effect, while 3% reported a negative effect.
Review this drug	View all 78 reviews	View all 32 reviews
Drug Class
PI3K inhibitors	BTK inhibitors	BTK inhibitors
Side Effects
Copiktra side effects	Ibrutinib side effects	Acalabrutinib side effects
Generic Availability
No lower cost generic approved	N/A	N/A
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card	Get free Discount Card

Dosage Forms Available
Oral capsule	N/A	N/A
Brand Names
N/A	Imbruvica	Calquence
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.
4.7 hours	6 hours	6.9 hours
CSA Schedule ** View glossary of terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
Summary unavailable. See the full pregnancy warnings document.	D Category D Positive evidence of risk See the full pregnancy warnings document.	Summary unavailable. See the full pregnancy warnings document.
Drug Interactions
A total of 615 drugs are known to interact with Copiktra: 167 major drug interactions (470 brand and generic names) 392 moderate drug interactions (1480 brand and generic names) 56 minor drug interactions (146 brand and generic names)	A total of 486 drugs are known to interact with Ibrutinib: 199 major drug interactions (694 brand and generic names) 283 moderate drug interactions (854 brand and generic names) 4 minor drug interactions (8 brand and generic names)	A total of 494 drugs are known to interact with Acalabrutinib: 213 major drug interactions (737 brand and generic names) 281 moderate drug interactions (925 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Grapefruit juice may increase the blood levels of certain medications such as duvelisib. You may... View more	Ibrutinib should be taken once daily at approximately the same time everyday. Do not consume... View more	Acalabrutinib may be taken with or without food. However, consumption of grapefruit and grapefruit... View more
Disease Interactions
Colitis Infections Hepatotoxicity Neutropenia	Arrhythmias Bleeding Cytopenia Hepatic impairment Hypertension Infections Renal impairment Tumor lysis syndrome	Arrhythmias Bleeding Hepatic impairment Infections Renal impairment
First Approval Date
September 24, 2018	November 13, 2013	October 31, 2017
WADA Class View World Anti-Doping Agency classifications.
N/A	N/A	N/A
More Information
Side effects Pregnancy warnings Breastfeeding warnings Dosage information Drug images Drug interactions Support group En Español	Side effects Pregnancy warnings Breastfeeding warnings Dosage information Drug interactions Support group En Español	Side effects Pregnancy warnings Breastfeeding warnings Dosage information Drug interactions Support group En Español
Patient resources
Copiktra uses	Ibrutinib uses	Acalabrutinib uses
Professional Resources
Prescribing information	Monograph (AHFS) Prescribing information	Monograph (AHFS) Prescribing information
Related Treatment Guide
Chronic Lymphocytic Leukemia	Waldenström Macroglobulinemia Chronic Lymphocytic Leukemia Graft Versus Host Disease	Chronic Lymphocytic Leukemia Mantle Cell Lymphoma

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copiktra Alternatives Compared

Further information

Compare Drugs