Climara Alternatives Compared
| Climara | Estradiol | Premarin |
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| Climara (estradiol) | Estradiol | Premarin (conjugated estrogens) |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Postmenopausal Symptoms, Oophorectomy, Hypoestrogenism, Primary Ovarian Failure, Prevention of Osteoporosis. Climara may also be used for... View more |
Prescription only
Estradiol is a synthetic form of estrogen that may be given for several different indications, including the relief of menopausal symptoms or low estrogen levels caused by other conditions. Its use... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Abnormal Uterine Bleeding, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more |
Related suggestions Postmenopausal Symptoms
Atrophic Vaginitis
Oophorectomy
Atrophic Urethritis
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| More about Climara (estradiol) | More about Estradiol | More about Premarin (conjugated estrogens) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Climara has an average rating of 6.2 out of 10 from a total of 62 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 28% reported a negative effect. |
Estradiol has an average rating of 5.7 out of 10 from a total of 579 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 39% reported a negative effect. |
Premarin has an average rating of 7.6 out of 10 from a total of 82 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Estradiol prices |
View all Premarin prices |
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| Dosage Forms Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Other estradiol brands include: Alora, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other conjugated estrogens brands include: Premarin Intravenous | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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16 hours |
16 hours |
N/A |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 364 drugs are known to interact with Climara:
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A total of 364 drugs are known to interact with Estradiol:
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A total of 245 drugs are known to interact with Premarin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
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| First Approval Date | ||||||||||||||||||
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December 22, 1994 |
July 23, 1975 |
May 08, 1942 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.