Comparing Chlorothiazide vs Hydrochlorothiazide
| Chlorothiazide | Hydrochlorothiazide |
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| Chlorothiazide | Hydrochlorothiazide |
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Prescription only
Prescribed for Edema, High Blood Pressure. chlorothiazide may also be used for purposes not listed in this medication guide. |
Prescription only
Hydrochlorothiazide (HCTZ) may be used to relieve edema (fluid retention) and to lower high blood pressure. A headache, dizziness on standing, dehydration, skin reactions, and depletion of... View more |
Related suggestions High Blood Pressure (Hypertension)
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| More about Chlorothiazide | More about Hydrochlorothiazide | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Chlorothiazide has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Hydrochlorothiazide has an average rating of 5.1 out of 10 from a total of 183 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 38% reported a negative effect. |
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| Side Effects | |||||||||||||||||
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See also: chlorothiazide side effects in more detail. |
See also: hydrochlorothiazide side effects in more detail. |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all chlorothiazide prices |
View all hydrochlorothiazide prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Diuril, Diuril Sodium | Aquazide H, Carozide, Diaqua, Esidrix, Ezide, Hydro Par, Microzide | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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2 hours |
12 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 459 drugs are known to interact with chlorothiazide:
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A total of 465 drugs are known to interact with hydrochlorothiazide:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 04, 1958 |
February 12, 1959 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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| Patient resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.