Comparing Chlorothiazide vs Chlorthalidone
| Chlorothiazide | Chlorthalidone |
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| Chlorothiazide | Chlorthalidone |
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Prescription only
Prescribed for High Blood Pressure, Edema. Chlorothiazide may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Edema, High Blood Pressure. Chlorthalidone may also be used for purposes not listed in this medication guide. |
Related suggestions High Blood Pressure (Hypertension)
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| More about Chlorothiazide | More about Chlorthalidone | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Chlorothiazide has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Chlorthalidone has an average rating of 4.0 out of 10 from a total of 49 ratings on Drugs.com. 20% of reviewers reported a positive effect, while 57% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Chlorothiazide side effects |
View all Chlorthalidone side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Chlorothiazide prices |
View all Chlorthalidone prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Diuril, Diuril Sodium | Hemiclor, Thalitone | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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2 hours |
37 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 466 drugs are known to interact with Chlorothiazide:
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A total of 482 drugs are known to interact with Chlorthalidone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 04, 1958 |
April 07, 1960 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.