Comparing Baclofen vs Xyrem
| Baclofen | Xyrem (sodium oxybate) |
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| Baclofen | Xyrem (sodium oxybate) |
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Prescription only
Baclofen relieves muscle spasms associated with multiple sclerosis and spinal cord injury or disease, but its use is limited by its ability to cause sedation and increase seizure risk. Prescribed for... View more |
Prescription only
Xyrem is a Schedule III controlled substance when prescribed to treat narcolepsy; however, there is a high risk of abuse associated with it and people who misuse it or sell it to other people are... View more |
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| More about Baclofen | More about Xyrem (sodium oxybate) | ||||||||
| Ratings & Reviews | |||||||||
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Baclofen has an average rating of 7.0 out of 10 from a total of 447 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 24% reported a negative effect. |
Xyrem has an average rating of 7.6 out of 10 from a total of 108 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Baclofen side effects |
View all Xyrem side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Xyrem prices |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Fleqsuvy, Gablofen, Lioresal, Lioresal Intrathecal, Lyvispah, Ozobax, Ozobax DS | Other sodium oxybate brands include: Lumryz | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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6.8 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 369 drugs are known to interact with Baclofen:
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A total of 346 drugs are known to interact with Xyrem:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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November 22, 1977 |
July 17, 2002 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.