Avandamet Alternatives Compared
| Avandamet (metformin / rosiglitazone) | Mounjaro (tirzepatide) | Semaglutide |
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| Avandamet (metformin / rosiglitazone) | Mounjaro (tirzepatide) | Semaglutide |
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Prescription only
Prescribed for Type 2 Diabetes. Avandamet may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Type 2 Diabetes. Mounjaro may also be used for purposes not listed in this medication guide. |
Prescription only
Semaglutide lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is taken... View more |
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| More about Avandamet (metformin / rosiglitazone) | More about Mounjaro (tirzepatide) | More about Semaglutide | ||||||||
| Ratings & Reviews | ||||||||||
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Avandamet has an average rating of 6.0 out of 10 from a total of 3 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 50% reported a negative effect. |
Mounjaro has an average rating of 8.6 out of 10 from a total of 1188 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 6% reported a negative effect. |
Semaglutide has an average rating of 6.9 out of 10 from a total of 2471 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Drug Class | ||||||||||
| Side Effects | ||||||||||
| Generic Availability | ||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Mounjaro prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms Available | ||||||||||
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N/A |
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| Brand Names | ||||||||||
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N/A |
Other tirzepatide brands include: Zepbound | Ozempic, Rybelsus, Wegovy | ||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||
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6.2 hours |
120 hours |
168 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||
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A total of 433 drugs are known to interact with Avandamet:
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A total of 413 drugs are known to interact with Mounjaro:
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A total of 272 drugs are known to interact with Semaglutide:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||
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| Disease Interactions | ||||||||||
| First Approval Date | ||||||||||
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October 10, 2002 |
N/A |
December 05, 2017 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||
| Patient resources | ||||||||||
| Professional Resources | ||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.