Comparing Auvelity vs Rexulti
| Auvelity (bupropion / dextromethorphan) | Rexulti (brexpiprazole) |
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| Auvelity (bupropion / dextromethorphan) | Rexulti (brexpiprazole) |
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Prescription only
Auvelity is an oral combination antidepressant tablet containing bupropion and dextromethorphan that has a novel way of working to treat adults with severe depression. Research has shown it is... View more |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Related suggestions Major Depressive Disorder
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| More about Auvelity (bupropion / dextromethorphan) | More about Rexulti (brexpiprazole) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Auvelity has an average rating of 8.6 out of 10 from a total of 140 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 6% reported a negative effect. |
Rexulti has an average rating of 6.6 out of 10 from a total of 490 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 26% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Auvelity side effects |
View all Rexulti side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Auvelity prices |
View all Rexulti prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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30 hours |
91 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 694 drugs are known to interact with Auvelity:
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A total of 599 drugs are known to interact with Rexulti:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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August 18, 2022 |
July 10, 2015 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.