Comparing Amitriptyline vs Prazosin
| Amitriptyline | Prazosin |
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| Amitriptyline | Prazosin |
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Prescription only
Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. It may be used off-label to treat other conditions such as... View more |
Prescription only
Prazosin effectively treats high blood pressure but commonly causes dizziness or lightheadedness on initiation or with a dosage increase. However, a tolerance to this effect develops on continued... View more |
Related suggestions Anxiety and Stress
Post Traumatic Stress Disorder
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| More about Amitriptyline | More about Prazosin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Amitriptyline has an average rating of 7.6 out of 10 from a total of 1805 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 16% reported a negative effect. |
Prazosin has an average rating of 6.9 out of 10 from a total of 281 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Amitriptyline side effects |
View all Prazosin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Amitriptyline prices |
View all Prazosin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Minipress | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 716 drugs are known to interact with Amitriptyline:
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A total of 273 drugs are known to interact with Prazosin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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April 07, 1961 |
June 23, 1976 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.