Comparing Amitriptyline vs Effexor
| Amitriptyline | Effexor (venlafaxine) |
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| Amitriptyline | Effexor (venlafaxine) |
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Prescription only
Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. It may be used off-label to treat other conditions such as... View more |
Prescription only
Effexor is an antidepressant that may cause a discontinuation syndrome if abruptly stopped after long-term administration. Prescribed for Autism, Major Depressive Disorder, Depression, Bulimia... View more |
Related suggestions |
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| More about Amitriptyline | More about (venlafaxine) | ||||||||
| Ratings & Reviews | |||||||||
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Amitriptyline has an average rating of 7.6 out of 10 from a total of 1805 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 16% reported a negative effect. |
Effexor has an average rating of 5.8 out of 10 from a total of 489 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 33% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Amitriptyline side effects |
View all Effexor side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Amitriptyline prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
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N/A |
Other venlafaxine brands include: Effexor XR | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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16 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 716 drugs are known to interact with Amitriptyline:
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A total of 700 drugs are known to interact with Effexor:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
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| First Approval Date | |||||||||
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April 07, 1961 |
N/A |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
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N/A |
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| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.