Comparing Acetaminophen / Hydrocodone vs Ibuprofen
| Acetaminophen / hydrocodone | Ibuprofen |
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| Acetaminophen / hydrocodone | Ibuprofen |
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Prescription only
Acetaminophen/hydrocodone may be used to treat moderate-to-severe pain that is unrelieved by nonopioid analgesics. However, its use is limited by the dependence and addiction potential of the... View more |
Prescription and OTC
Ibuprofen is effective for the short-term relief of minor aches and pains and also reduces inflammation. The risk of stomach-related side effects is about half that seen with aspirin although the... View more |
Related suggestions Rheumatoid Arthritis
Back Pain
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| More about Acetaminophen / hydrocodone | More about Ibuprofen | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Acetaminophen / hydrocodone has an average rating of 6.0 out of 10 from a total of 1316 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 35% reported a negative effect. |
Ibuprofen has an average rating of 7.4 out of 10 from a total of 237 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Acetaminophen / hydrocodone prices |
View all Ibuprofen prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Xodol, Zyfrel | A-G Profen, Actiprofen, Addaprin, Advil, Advil Children's, Advil Film-Coated, Advil Infant's Concentrated Drops, Advil Junior Strength, Advil Liqui-Gels, Advil Migraine, Caldolor, Cap-Profen, Children's ElixSure IB, Children's Motrin, Childrens Ibuprofen Berry, Genpril, Help I Have An Aching Body, IBU-200, Midol IB, Midol Maximum Strength Cramp Formula, Motrin, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Motrin Pediatric, NeoProfen, Nuprin, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Proprinal View more | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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3.8 hours |
4 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 646 drugs are known to interact with Acetaminophen / hydrocodone:
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A total of 398 drugs are known to interact with Ibuprofen:
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| First Approval Date | |||||||||||||||||
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May 03, 1982 |
September 19, 1974 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.