Comparing Acetaminophen / Hydrocodone vs Hydrocodone / Ibuprofen
| Acetaminophen / hydrocodone | Hydrocodone / ibuprofen |
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| Acetaminophen / hydrocodone | Hydrocodone / ibuprofen |
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Prescription only
Acetaminophen/hydrocodone may be used to treat moderate-to-severe pain that is unrelieved by nonopioid analgesics. However, its use is limited by the dependence and addiction potential of the... View more |
Prescription only
Prescribed for Pain. Hydrocodone / ibuprofen may also be used for purposes not listed in this medication guide. |
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| More about Acetaminophen / hydrocodone | More about Hydrocodone / ibuprofen | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Acetaminophen / hydrocodone has an average rating of 6.0 out of 10 from a total of 1315 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 35% reported a negative effect. |
Hydrocodone / ibuprofen has an average rating of 8.5 out of 10 from a total of 74 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 7% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Hydrocodone / ibuprofen side effects |
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| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Acetaminophen / hydrocodone prices |
View all Hydrocodone / ibuprofen prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Xodol, Zyfrel |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.8 hours |
4.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 679 drugs are known to interact with Acetaminophen / hydrocodone:
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A total of 872 drugs are known to interact with Hydrocodone / ibuprofen:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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May 03, 1982 |
September 23, 1997 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.