Comparing Acetaminophen / Caffeine vs Ibuprofen
| Acetaminophen / caffeine | Ibuprofen |
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| Acetaminophen / caffeine | Ibuprofen |
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Over-the-counter
Prescribed for Headache, Osteoarthritis, Pain, Period Pain, Cold Symptoms, Sinusitis. Acetaminophen / caffeine may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Ibuprofen is effective for the short-term relief of minor aches and pains and also reduces inflammation. The risk of stomach-related side effects is about half that seen with aspirin although the... View more |
Related suggestions Osteoarthritis
Headache
Period Pain (Dysmenorrhea)
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| More about Acetaminophen / caffeine | More about Ibuprofen | ||||||||
| Ratings & Reviews | |||||||||
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Acetaminophen / caffeine has an average rating of 9.5 out of 10 from a total of 8 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Ibuprofen has an average rating of 7.3 out of 10 from a total of 240 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Ibuprofen side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Ibuprofen prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Excedrin Mild Headache, Excedrin Quick Tab, Excedrin Tension Headache, Headache Relief | A-G Profen, Actiprofen, Addaprin, Advil, Advil Children's, Advil Film-Coated, Advil Infant's Concentrated Drops, Advil Junior Strength, Advil Liqui-Gels, Advil Migraine, Caldolor, Cap-Profen, Children's ElixSure IB, Children's Motrin, Childrens Ibuprofen Berry, Genpril, Help I Have An Aching Body, IBU-200, Midol IB, Midol Maximum Strength Cramp Formula, Motrin, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Motrin Pediatric, NeoProfen, Nuprin, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Proprinal View more | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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4 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 246 drugs are known to interact with Acetaminophen / caffeine:
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A total of 413 drugs are known to interact with Ibuprofen:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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N/A |
September 19, 1974 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
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N/A |
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| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.