Comparing Acalabrutinib vs Methotrexate
Acalabrutinib | Methotrexate |
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Acalabrutinib | Methotrexate |
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Prescription only
Prescribed for Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma. acalabrutinib may also be used for purposes not listed in this medication guide. |
Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
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More about Acalabrutinib | More about Methotrexate | ||||||||
Ratings & Reviews | |||||||||
Acalabrutinib has an average rating of 9.0 out of 10 from a total of 25 ratings on Drugs.com. 91% of reviewers reported a positive effect, while 4% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 334 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
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Drug Class | |||||||||
Side Effects | |||||||||
See also: acalabrutinib side effects in more detail. |
See also: methotrexate side effects in more detail. |
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Generic Availability | |||||||||
N/A |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all methotrexate prices |
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Dosage Forms Available | |||||||||
N/A |
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Brand Names | |||||||||
Calquence | Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | ||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
6.9 hours |
15 hours |
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CSA Schedule ** View glossary of terms | |||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Summary unavailable. See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 478 drugs are known to interact with acalabrutinib:
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A total of 694 drugs are known to interact with methotrexate:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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Disease Interactions | |||||||||
First Approval Date | |||||||||
August 03, 2022 |
December 07, 1953 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient resources | |||||||||
Professional Resources | |||||||||
Related Treatment Guide | |||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.