Comparing 5-HTP vs Prozac
| 5-HTP (5-hydroxytryptophan) | Prozac (fluoxetine) |
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| 5-HTP (5-hydroxytryptophan) | Prozac (fluoxetine) |
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Over-the-counter
Used for ADHD, Anxiety, Insomnia, Headache. 5-HTP may also be used for purposes not listed in this medication guide. |
Prescription only
Prozac may be used for the treatment of depression and other mood disorders. It is more likely to cause insomnia than drowsiness. Prescribed for Anxiety and Stress, Major Depressive Disorder... View more |
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| More about 5-HTP (5-hydroxytryptophan) | More about Prozac (fluoxetine) | ||||||||
| Ratings & Reviews | |||||||||
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5-HTP has an average rating of 6.6 out of 10 from a total of 155 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 25% reported a negative effect. |
Prozac has an average rating of 7.2 out of 10 from a total of 1239 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all 5-HTP side effects |
View all Prozac side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Prozac prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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4 hours |
210 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category N
Not classified
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 99 drugs are known to interact with 5-HTP:
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A total of 681 drugs are known to interact with Prozac:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||
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N/A |
December 29, 1987 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.