5-HTP Side Effects
Generic name: 5-hydroxytryptophan
Note: This document provides detailed information about 5-HTP Side Effects associated with 5-hydroxytryptophan. Some dosage forms listed on this page may not apply specifically to the brand name 5-HTP.
Applies to 5-hydroxytryptophan: oral capsule, oral tablet, oral tablet disintegrating, oral tablet extended release.
Important warnings
This medicine can cause some serious health issues
Follow all directions on the product label and package.
Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Stop using 5-hydroxytryptophan (the active ingredient contained in 5-HTP) and call your healthcare provider at once if you have:
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slow heart rate, feeling like you might pass out;
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skin rash, bruising; or
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racing thoughts, increased energy, decreased need for sleep, risk-taking behavior, being agitated or talkative.
Common side effects may include:
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drowsiness, sleep problems (insomnia);
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headache, dizziness, weakness;
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altered sense of taste, appetite or weight change;
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muscle problems;
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severe vomiting, stomach pain, heartburn;
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diarrhea, constipation; or
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sexual problems.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
More about 5-HTP (5-hydroxytryptophan)
Patient resources
Professional resources
Related treatment guides
Further information
5-HTP side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.