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Zometa and Fever: What Users Say

Fever: mentioned by 7 users (15.9%)

Based on user experiences from 44 Zometa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

chills 22.7%
pain 22.7%
fever 15.9%
flu-like symptoms 13.6%
joint pain 13.6%
body aches 11.4%
bone pain 11.4%
headaches 11.4%
tiredness 11.4%
back pain 9.1%

Reviews for Zometa

Commonly mentioned side effects
  • jak...
  • Taken for less than 1 month
  • June 6, 2019

For Osteoporosis "For four weeks, I had little to no appetite and periods of tiredness. For the first 3 weeks, I was also in a stupor, tired, and weak every day, with nausea daily. Along with these symptoms, for the first 2 weeks, I had on and off fever, chills, headache, no energy, sweats at night. I felt like I was drugged and was weak, unstable, and sick. I would never, never take Zometa again, and I do NOT recommend it."

2 / 10
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115 Report
  • Jan...
  • December 11, 2016

For Osteoporosis "Had the infusion - 15 minutes - 4 days ago. On the day, felt fine. The next day, thought I was dying, chills, fever, nausea, whole body/bones/joints extremely painful. Woke up every hour and had to drink water. Day 3, felt a lot better and managed to go to work. Day 4, I feel fine. Not sure how effective it will be, will have to have a bone scan in a year's time!"

8 / 10
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50 Report
  • dch...
  • Taken for less than 1 month
  • January 29, 2022

For Osteoporosis "I am 65 and consider myself strong and overall healthy. I will never have this infusion again. My side effects included vomiting, diarrhea, fever, severe neck pain, joint pain including thumbs and knees, and my nose hurt. On my oncologist's suggestion, I had a COVID test, and it came back negative for COVID or the flu. Now, after 17 days, I am still experiencing flu-like symptoms, late-day fatigue, and just an overall blah feeling. I had a breast cancer lumpectomy in August and 4 weeks of radiation. I do not see any benefit of this drug and will try something else to get the calcium in my bones as the side effects are absolutely horrible."

1 / 10
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21 Report

Frequently asked questions

  • Nan...
  • Taken for less than 1 month
  • March 18, 2021

For Osteolytic Bone Metastases of Solid Tumors "My oncologist, for some reason, changed my medication from Exgiva to this medication. I have been having the worst side effects ever. I have bone pain, stomach pain, fever, and chills. I am on the 5th day, and I’m still experiencing chills and fever. I would never take this medication again. I just wonder how long this is going to last. If I ever get better."

1 / 10
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13 Report
  • Sed...
  • Taken for 1 to 6 months
  • July 17, 2021

For Osteolytic Bone Lesions of Multiple Myeloma "I was placed on Zometa by my oncologist as a preventive medication to avoid bone lesions and fractures. I was diagnosed with multiple myeloma earlier in the year. I fortunately do not have bone issues at this point, however, my doctor thought it might help with prevention. After my first infusion, I developed severe chills, fever, and terrible calf pain 24 hours later. The fever, chills, and pain fortunately disappeared about a day or two later, but the fatigue lasted for days. Before my second monthly infusion, I drank more water. This did seem to help with avoiding chills and fever, but 24 hours later, I again developed bad calf pain and realized I had edema in my legs. A day later, it is better, but again, I have horrible fatigue and bloating. The side effects of this medicine are worse than those of my cancer meds. I will have to talk to my doctor, as I am not willing to do this every month unless I really have to."

2 / 10
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6 Report

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  • t12...
  • Taken for less than 1 month
  • June 6, 2024

"Just had my first infusion, will need 2 every 6 months for 3 years. Make sure you drink lots of water, my side effects were mild. I did have a high temperature which I took paracetamol."

8 / 10
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  • rob...
  • Taken for less than 1 month
  • January 22, 2015

For Osteolytic Bone Metastases of Solid Tumors "IV Zometa yesterday. Woke up this morning, body aches, headache, fever, slept all day."

2 / 10
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18 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.