Reclast and Fever: What Users Say

• Fir...
• April 23, 2020

For Osteoporosis "I am 51 years old with no health issues, and had my first Reclast infusion one week ago. After the 10 am procedure, I felt ok until the evening, at which time I developed a 101-degree fever, chills, elevated pulse, headache, nausea, vomiting, and diarrhea. I did not take Tylenol or pain relievers of any kind, either before or after the procedure, although most of you will be advised to do so (as was I). By the next morning, I felt much better, but definitely not back to normal. But felt increasingly better as the day progressed, to the point that in the afternoon, I was able to resume my weightlifting and walking routine. By the next morning, I was back to 100%, feeling wonderful and eating well. I have felt great ever since. I hope this post will make you feel better if you have a bad first night. Hang in there, my prayers are with you!"

• Mcm...
• Taken for 6 months to 1 year
• June 2, 2020

For Osteoporosis "Short & sweet - Never, ever again will I take this drug. This knocked me on my butt and took everything out of me for several days. The worst headache I've ever had in my life (could not even open my eyes it hurt so much), excruciating bone pain (pain you don't understand unless you've experienced it), fever, severe weakness, etc. My doctor was extremely vague and aloof. When I called to explain what I was experiencing and asking if I should go to the hospital because seriously I thought I was dying, he was so callous and unsympathetic and just said 'yeah, those are side effects, just take Tylenol'. It's been a year and I still have negative effects of this drug! Awful experience!"

• the...
• Taken for less than 1 month
• August 29, 2020

For Osteoporosis "I had my first infusion on August 27, 2020. I had an appointment on August 25, 2020, with my primary care doctor. I was diagnosed with osteoporosis recently. I'm 64 years old. She told me this was the same medicine that the oral was. I tried the oral for a few months, but it made me severely constipated. So I asked what the side effects were, and she says constipation, lol. She didn't mention the preparation before receiving the infusion. Six hours later, the body aches and fever started. Then the nausea started. Then the vomiting. My highest temperature was 103. Taking Tylenol helped bring down the fever some, but after it wore off, it would come back. Today, my bones hurt so bad I can hardly move. My ribs hurt to the point I feel like they are broken. I'm not sure I want to go through this again."

• Gai...
• August 23, 2020

For Osteoporosis "I’m a 63-year-old woman who had my first Reclast infusion on August 6th. So I’m 17 days out. Today I’m experiencing the worst joint pain in my legs, hips, arms, and the worst is in my neck. It seems like it is progressively getting worse. I’m trying so hard to remain hopeful that this disappears. It’s very hard to get out of bed each morning. Also, I was the one that the flu-like symptoms hit me hard at midnight right after I had the infusion. Worst chills ever. Couldn’t control them. My husband thought I was having convulsions. Fever spiked to 103.7. Those symptoms were gone after 3 days. But, the joint pain is more than awful. I’m looking to hear from someone with the same symptoms that the pain actually went away after a while. Don’t know if I can do this again. I had been on Prolia and it didn’t work as the doctor expected."

• rsh...
• Taken for less than 1 month
• June 9, 2021

For Osteoporosis "I am a 59-year-old male with a L spine T Score of -3.9. I had ignored my osteoporosis for many, many years until I felt that I had no choice but to do something. As a radiologist, I have seen many a spine with osteoporosis and multiple compression fractures that significantly reduce quality of life, so I took the risk. I hydrated prior to infusion but did not immediately take NSAIDs. What a mistake. Eight hours after infusion (3 AM), I started to have severe, uncontrollable rigors (shaking chills) and diffuse bone and muscle pain that I have never experienced before. As a reference point, I fractured my right pelvis years before in the Navy, and I know what pain is. Fever and chills improved with NSAID (first tried Tylenol and may switch to Naprosyn). The pain is still severe. The other testimonials are scary, but I also know that there is no free lunch in medicine. Everything we do is a balance between what helps and what does not."

• Anonymous
• June 29, 2020

For Osteoporosis "I had my first infusion of Reclast in early March 2020. Within a day, I was in the ER. I suffered greatly with nausea, vomiting, extreme bone pain, and fever. The fever, loss of appetite, fatigue, malaise, and other symptoms lasted for 21 days. My rheumatologist was beside herself with worry yet very helpful and compassionate. I could not eat more than toast and soup and kept a thermometer and Tylenol at bedside to treat the recurring fever. By the way, I tested negative twice for Covid-19 with a negative antibody test so coronavirus was excluded as the cause. Please do your research when deciding on an osteoporosis drug. I cannot rate the effectiveness until my next DEXA scan in 2021. But in the words of my doctor, 'never, ever again will you receive Reclast.'"

• Lat...
• Taken for less than 1 month
• April 15, 2021

For Osteoporosis "The doctor never explained to me the adverse effects of this drug. I had a slight fever and severe joint pain, a headache worse than the COVID-19 vaccine. It is now 20 days since I had it and the severe joint pains still persist. I am very upset because they did not prepare me for it, now I have to take Tylenol when I had never done it before, in addition to vitamin D and calcium. Also, my platelets were high. The doctor says he does not know if the combination between the COVID-19 vaccine and this drug is the problem, and they claim it has to do with it. Anyway, I still have bone pains... The medicine came out worse than the disease!!!"

• Cou...
• Taken for less than 1 month
• May 25, 2022

For Prevention of Osteoporosis "I was told by the nurse administering the Reclast infusion that I might be 'a little sore.' That was the understatement of the century! Almost immediately, I got a severe headache. By bedtime, I was in excruciating pain in the chest, abdomen, back, shoulders, hips, limbs, fingers, and toes. In other words, EVERYWHERE! The following day, my temperature shot up to 103.7, and the pain in my chest and abdomen was so severe that I could only take small, shallow breaths. I went to the ER where every test known to man was performed. Nothing. The ER doctor finally said my symptoms could only be attributable to the Reclast. It’s now Day 3, and there's been no relief except my temperature is now normal. Horrible experience!"

• Lei...
• Taken for 1 to 2 years
• February 25, 2020

For Osteoporosis "My first infusion with Reclast was rough. Side effects lasted 2-3 weeks. I already have Psoriatic Arthritis, and a high tolerance for pain. But I was so sick with pain and nausea, I dreaded the next treatment. 6 days ago, I did it again, believing the side effects would be less. They aren’t. I can hardly get out of bed. All my bones and joints ache. I ran a low-grade fever the first 2 days and vomited. I feel like I have shin splints and all I want to do is sleep. I know the medication works, but for some of us, it’s terribly difficult."

• KMN...
• Taken for less than 1 month
• May 11, 2022

For Prevention of Osteoporosis "I have Osteopenia due to being on an estrogen blocker after breast cancer. Prolia was scheduled. When I arrived, I was told insurance wanted Reclast. Therefore, NO prep instructions. I typically drink 64 oz of water every day. Had been taking VitD/calcium for 7 days. Was told Tylenol and loratadine would really help IF I had bone pain. About 6 hours after the 30-minute infusion, I got really tired/sleepy. Also, forehead area headache & low-grade fever. Took XS Tylenol. Felt better, continued hydration. Took Tylenol again about 5 hours later. Went to bed, ribs, shoulders, feet, fingers pain. I'd rate an 8. This is with my normally prescribed pain meds in addition to Tylenol. Hard shaking chills, continuing pain, nausea. More Tylenol, added Zofran for nausea. Only able to sip water... tried ginger ale sips. So I am 6 hours in and writing this while there is a break in chills. Pain now 6. Would not choose this medicine."

• Anonymous
• Taken for less than 1 month
• July 22, 2021

For Prevention of Osteoporosis "My mother is very healthy at 83. She takes only one medication for reflux, has full mental capacity, and above-average strength. She had one infusion resulting in severe bone/joint pain, high fever, complete incoherence, a cough, dizziness, and ocular palsy. C-19 was ruled out, as were other diagnoses. After eight months, some of these symptoms continue. Since this Rx is supposed to be given in a series of three, the full effectiveness will not be realized since she obviously will not be getting the remaining two infusions. Do not, under any circumstances, inject this stuff into your body. Find some alternative therapies and supplements instead."

• ish...
• Taken for less than 1 month
• June 15, 2023

For Osteoporosis "I am a 55-year-old female with a complicated medical history. Due to high amounts of cortisone during my childhood, I have compromised bones. Despite this, I agreed to receive the Reclast infusion on June 1st. In the afternoon of the same day, around 11 PM, I experienced a fever of 103.3°F, accompanied by body shivering and teeth chattering. It was quite frightening as I live alone. I took Tylenol, although it was challenging to retrieve due to my condition. The fever persisted for two days, reaching 103.3°F again. I contacted my doctor on Sunday, and he acknowledged that it was unusual but assured me it would subside. However, for the following week, I continued to experience fevers ranging from 101°F to 100.5°F. Frustrated, I reached out to my doctor again, expressing my dissatisfaction. During my appointment on Monday, he mentioned that he had never encountered such cases, but a senior doctor had seen similar situations and explained that it might take a few weeks to resolve. Every day, I still have a low-grade fever, which makes me feel unwell, but I have to continue working. I have decided that I will never take Reclast again. Furthermore, I am disappointed with my doctor's reaction and his inability to provide empathy. His demeanor has been peculiar throughout this experience. In conclusion, I do not recommend this treatment."

• Sno...
• Taken for less than 1 month
• December 16, 2019

For Osteoporosis "I had this infusion of Reclast for Osteoporosis. I have had a rib fracture and L1 compression fracture. The next morning after the injection, I had side effects of flu symptoms, fever, and chills. The worst is the severe joint pain. My knees are so swollen and stiff that I am unable to walk without a cane or assistance. Also, my thumbs are swollen and painful. It has been 3 days, so I can’t really say if any of this is worth it. But, I don’t think I would use this drug again. I’m being told by the doctor that it may take a week to several weeks for the side effects to subside."

• 202...
• Taken for less than 1 month
• March 25, 2023

For Prevention of Osteoporosis "I had my first and only Reclast infusion 23 days ago. About 9 hours after the infusion, I started feeling ill, I had terrible chills, shaking violently for two hours. At 2:00 a.m., I went to the ER with a fever of 102.4 and pain everywhere. I had heart surgery to repair my mitral valve 2 1/2 years ago and have been taking an arrhythmia drug for 2 years, and I’ve been fine. Since the infusion, I am tired, I have a fib and bigeminy several times a day, chest pain, and unbearable calf pain. This drug has ruined my health and my life. Do not take it."

• Deb...
• Taken for less than 1 month
• August 23, 2019

For Osteoporosis "I had a Reclast infusion on 8/20/2019 for the first time. It took about 30 minutes to receive all of the medication. I was given water to drink while there. I left, did some errands, and felt fine. I had dinner with a friend and still felt great. I went to bed and woke up about 12 hours after receiving my dose with severe clavicle and neck pain. I took 500mg of Acetaminophen and started drinking water. I was concerned that I hadn’t consumed enough water prior to taking the treatment. I probably consumed close to 64 ounces of water during this time. The pain subsided enough for me to fall asleep around 8:00 am, and when I woke up later, my body felt achy, and I had a low-grade fever. Those symptoms were uncomfortable but tolerable compared to the severe pain earlier. I continued to take Acetaminophen to help with the aches and fever and woke up on day two feeling fine. In summation, my negative symptoms only lasted 24 hours."

• DR ...
• Taken for less than 1 month
• June 13, 2023

For Prevention of Osteoporosis "After having a Reclast injection, I had three days of low fever of 100.5, headache, stomach ache, and lupus-like rashes. It reduced renal function and caused dark, foaming urine. More harm than any good to my health, a huge mistake."

• Mar...
• May 25, 2019

For Osteoporosis "I chose Reclast over Prolia because of the cost savings. The infusion was given at 9 am and 7 pm. On that night, I was experiencing severe bone pain, fever, sweats, and blurred vision. The pain was so great that all I could do was moan and cry. This lasted for two days, and then the pain lessened. By early morning of day 3, I began to have chest pain. The pain came and went every few minutes for 15 hours. When I called to ask for pain medication, his response was, 'I’m not actively treating you for cancer, go to your primary care doctor.' My oncologist prescribed me this poison, and he didn’t want to help me. When the chest pain started, I begged to come into his office just to check me out. I felt like I was going to die, and their response was 'we can’t do anything for you, go to the ER.' Absolutely no empathy for his patient and clearly did not care for my well-being, physically or mentally. I will never take this drug again! Beware of taking Reclast."

• Luc...
• November 22, 2016

For Osteoporosis "Hard to tell if this drug worked yet or not but it definitely made me sick. Got the infusion Friday and on Saturday I had a 102 Fever and could barely get out of bed. I had chills, I'm sweating all over the place, and my husband literally had to help me to the bathroom. I was dizzy and every bone in my body ached. By Sunday afternoon, I was a little bit better but four days later I'm still feeling achy and have diarrhea. I won't be doing another infusion."

• Ant...
• Taken for 1 to 2 years
• August 30, 2017

For Osteoporosis "Last year's infusion brought four days of fever, made difficult because I can't take aspirin or other non-steroidal anti-inflammatories. After two weeks, I'm nostalgic for those symptoms. This time body temp has stayed in the 96.4 range (95.9 this a.m.), when it's usually 97.6-98.6, so I feel very cold-until I get a savage hot flash requiring me to mop myself off with a towel, at least once an hour. I also have muscle cramps waking me up several times a night (more than prior to treatment). I've been lightheaded and fatigued. I also have fibromyalgia, but these symptoms are different/more intense. The doc told me he can do nothing. I'm frantic because I need to work and find that almost impossible. Anyone else with a situation like mine?"

• jmo...
• Taken for less than 1 month
• May 18, 2023

For Prevention of Osteoporosis "Received the first dose of Reclast yesterday, and never again. I can tolerate the fever, chills, and even fatigue, but the severe muscle pain is nothing like I've ever experienced before. The flu, COVID, and COVID vaccine side effects are a walk in the park compared to the Reclast muscle pain. This was my first and last dose. I didn't tolerate oral Fosamax either, so I'm done with osteoporosis treatment."

• ste...
• Taken for less than 1 month
• January 14, 2020

For Osteoporosis "I had the Reclast infusion less than 1 week ago. First day seemed fine until the evening, then a headache started. Ended up in bed for 2 days due to exhaustion, body aches, fever, and a severe headache. 3rd day, the pain in my thumbs started, barely able to use my hands. 4th day, I experienced neck pain, and I'm almost afraid of what else might come up. I'm debating whether or not I'll take this again next year. I'm unable to do my normal exercise and stretching due to joint pain."

• sun...
• Taken for 1 to 6 months
• September 15, 2016

For Osteoporosis "Received dose at 11am, by 10pm that night I had fever, chills, severe pain in back. I was extremely ill for 3 days, such a severe headache I couldn't open my eyes. A week later my hands suddenly swelled to the point I could not use them. Now nearly 3 months later I am in physical therapy to try to regain the strength in my legs. Other side effects were less severe, such as jaw pain for a few weeks. I would never ever take this medicine again."

• Hon...
• Taken for less than 1 month
• February 6, 2025

For Osteoporosis "I’m a 57-year-old woman. I had my first infusion of Reclast Monday morning. I drank water during the procedure. I was not informed to drink water prior. I felt fine after the infusion. By the evening, I started feeling achy. Tuesday, I couldn’t go into work. I had a 101.6 fever, shaking, chills, joint pain, migraine, all-over body aches, and slept pretty much all day. I cannot take Tylenol due to another medical condition, so I took Naproxen 2x that day. Wednesday, I woke up without chills, a temperature of 99.4, and ate a little something. I still feel achy and hope to feel better tomorrow. I’m rethinking taking this medication ever again. Very painful side effects."

• Wil...
• Taken for less than 1 month
• May 24, 2022

For Prevention of Osteoporosis "Horrible. Within 48 hours of infusion, I developed chills, fever 101.4, subsequent joint pain, and then swelling in the carpometacarpal joint. Right knee started with pain, and within 24 hours, I had a complete knee effusion with inability to bear weight. Knee was swollen twice its size."

• Suz...
• Taken for 1 to 6 months
• May 7, 2019

For Osteoporosis "I had the Reclast infusion on April 4th, and 12 hours later I had severe chills (shaking so bad I couldn't close my mouth to take my temp) and fever. Lasted for 6 hours. Then I was sick to my stomach for the next day with severe pain in my legs (hard to get up from a chair) and my hands (hurt to write). Then I started with a 'cold' sinus/bronchial infection, which sent me to urgent care for an inhaler and cough medicine. Back to the doctor after 5 days for antibiotics, and I'm still sick one month later. Now jaw pain on the left side, and my teeth hurt. I will NEVER take Reclast EVER again. I hope you won't either!!!"