Venetoclax and Muscle Aches: What Users Say

• Eam...
• Taken for less than 1 month
• November 2, 2024

For Chronic Lymphocytic Leukemia "Worked very quickly to bring my counts close to normal (within 2 weeks) after a 3-month buffering period on ibrutinib. I do eat twice what I normally would, and I am craving protein. I am not putting on weight nor losing weight. Only side effect is a strange muscle soreness, but I am not sure if that is DOMS from exercise, the drug itself, or I recovered poorly from an exercise session due to the drug. Early days, but a very positive experience. All other bloods normal. Incredible how quick it worked for me."

• Lou...
• Taken for 6 months to 1 year
• May 26, 2024

For Chronic Lymphocytic Leukemia "I am just ending month 11 of venetoclax, teaming it up with obinutuzumab for the first 6 months. My blood work has been normal for 6 months. A bone marrow biopsy showed no CLL cells last week. I experienced sore joints, sore muscles, and a cumulative (worsening) lack of energy and exhaustion. It seemed to be worse month after month. I also gained 60 pounds over the 11 months of treatment. I worked up to 400 mg daily. I am looking forward to stopping venetoclax and hope these troublesome side effects dissipate."

• Jon...
• Taken for 6 months to 1 year
• May 23, 2023

Venetoclax for Chronic Lymphocytic Leukemia "Worked on fixing blood counts but caused side effects over time and had to stop. I had extreme muscle pain and gained about 20 pounds in about a year. Previously had FCR chemo and then ibrutinib."