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Trimethoprim for Urinary Tract Infection User Reviews (Page 2)

Brand names: Primsol

Trimethoprim has an average rating of 3.0 out of 10 from a total of 141 reviews for the treatment of Urinary Tract Infection. 11% of reviewers reported a positive experience, while 72% reported a negative experience.

Reviews for Trimethoprim

  • Kitcat
  • Taken for less than 1 month
  • May 18, 2022

"I wish I had read the damning reviews on here prior to taking this. Was given 200mg twice a day for 10 days. After 1st tablet felt a little numb, took my second at bedtime and that’s where the complete unravelling of my physical and mental well-being started. I woke up literally unable to move, my body was so weak, I had severe kidney pain and shooting pains up my spine. I felt really weird and very very scared. I tried to get up and collapsed, I shook uncontrollably and started to burn up. The anxiety and panic attacks were so debilitating I thought I had had a mental breakdown, I lay in pain rocking and muttering for hours in complete panic not knowing what to do or how to make it stop. A friend came over and looked after me for hours while I just cried uncontrollably and apparently talked about some really strange things! Scary doesn’t even come close to it, I actually thought my life was over. I will never take this again not if someone paid me a lot of money to do so. Ban it!"

1 / 10
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21 Report
  • 123
  • Taken for less than 1 month
  • March 4, 2022

"Was prescribed 200mg twice a day for uti & possible kidney infection for 5 days. Not even an hour after the 1st pill hit my system I was throwing up, shaking, agitated, having horrific thoughts, anxiety, couldn't stand and had such bad fatigue I could hardly lift my head off the pillow. Also had facial bone pain along my jaw and cheekbones. After my 3rd day (today 4th March 22) my doctor advised to stop & switch to a different antibiotic as I am just not coping on these. I'd rather sit in the bath for hours on end drinking cranberry juice and water to flush out the uti than ever take these again!"

1 / 10
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21 Report
  • Anonymous
  • Taken for less than 1 month
  • March 23, 2023

"I had a very bad experience with this antibiotic. I totally lost my mind. All the usual levels of anger, fear, hurt were multiplied by 100. Thoughts totally dark with my heart pounding like crazy. I ended up smashing plates! I couldn’t sleep. I saw the reviews from other people. Stopped the antibiotic and after a day I feel shattered but myself again. This could have been so dangerous. Please if you experience something similar: you will be ok, just stop taking this antibiotic. After reading other people’s reviews this drug should really be taken off the market. It could be dangerous, especially for people already with vulnerable mental health. All the best to you"

1 / 10
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13 Report

Frequently asked questions

  • JettaJB
  • Taken for less than 1 month
  • March 20, 2020

"This antibiotics trimethoprim is good for treating UTI’s but give awful side effects Had 3 days worth of these and although cleared up infection came with some unwanted feelings worse side effects were migraine type headaches fatigue shakes nausea and racing heart Absolutely awful wouldn’t want to take these again thank god it was only 3 days!"

3 / 10
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28 Report
  • Stu
  • Taken for less than 1 month
  • January 1, 2020

"Given 200 mg twice a day for 2 weeks. The UTI cleared up ok, but I had severe anxiety & intrusive thoughts after 2 days. It was one of the worst 2 weeks of my life. I will NEVER take this medication again. (3 days after the 2 week course of medication was completed my thinking returned to normal, and my anxiety disappeared.)"

2 / 10
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29 Report

Are you taking this medicine?

  • Kerry
  • Taken for less than 1 month
  • May 23, 2023

"OMG I have never experienced an antibiotic so awful in my life than Trimethoprim 200mg twice a day for seven days. Pains, anxiety, migraine, shortness of breath and tearful. Hot flashes. I nearly fainted I felt so ill. Stopped them Sunday and hoping I feel myself again soon."

1 / 10
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10 Report
  • Florana
  • Taken for less than 1 month
  • September 21, 2020

"Had trimethoprim for a UTI, one a day. The first night I had the most horrible acid reflux all night, woke up the next morning with the sorest throat in the world and about 2 hours sleep. Then after night 2, I experienced a massive headache where I couldn't put my headset on to work and I felt so tired. By night 3 I was a bit itchy on my arms and a rash developed but the UTI had gone by then, so I stopped treatment. If a Dr recommends alprim again I'm going to say no."

6 / 10
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21 Report
  • Blue
  • October 9, 2018

"I took three day course. From day 2 bad headache, weariness and aching. Had to sleep on day 3. After stopping, was ill for 2 days with exhaustion, terrible headaches, toothaches, and pain throughout my body. I will never take this dangerous drug again."

1 / 10
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28 Report
  • Jazz
  • Taken for less than 1 month
  • June 5, 2018

"I was give 4 days of trimethoprim for a UTI . After the first tablet it brought on intense anxiety and panic attacks and I couldn’t sleep. I stopped it after the second day and it went away. It was awful will never touch it again !!!"

1 / 10
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28 Report
  • Sandy
  • Taken for less than 1 month
  • December 8, 2018

"Awful medication. Took for 2 1/2 days and had to stop taking. Symptoms: -Acute pain in arms, legs, groin. Difficulty in moving to fingers etc. -Fever -Headache -Red eyes -Rash on leg -Stiff neck -Back pain -unable to sleep To make matters worse... bladder pain still there. Will never take again!"

1 / 10
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  • Clive
  • Taken for less than 1 month
  • September 5, 2020

"Was prescribed a 3 day course of Trimethroprim here in the UK for a UTI ( I have a history of these infections). I managed to complete the course & it does appear to have resolved the infection, but by day 2 I had developed a crippling headache that nothing would shift, so bad it some times hurt just to move my head. Don't know what I would have done if the course had been longer - I advise caution as the headache is deeply unpleasant."

5 / 10
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19 Report
  • Liz
  • May 26, 2021

"Day 3 and this drug has made absolutely no difference at all. I recall this exact same thing happening last time I had a UTI (a while ago now) and I was changed to a different antibiotic. My experience has not been a good one at all."

1 / 10
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16 Report
  • Extreme...
  • February 15, 2013

"After several bouts of urinary tract infections while awaiting prolapse surgery - bladder unable to void efficiently - I experienced extremely severe mouth ulcers on each occasion, lasting three weeks. I was told this was probably because I was "run down". However, most recently, half an hour after taking the first dose of Trimethoprim I experienced intense burning of my lower lip, accompanied by extreme swelling. Recognising this as the start of the severe mouth ulceration I had experienced previously on numerous occasions, I informed my doctor, who immediately prescribed antihistamine and told me to stop taking the Trimethoprim, substituting another antibiotic. "

1 / 10
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41 Report
  • Aano
  • Taken for less than 1 month
  • May 1, 2020

"I'm on day 3 of this medication and before reading these reviews I have had a migraine that won't go away, shaky hands, trembling, paranoid, dry mouth, nausea and the itchiest skin. These are all of the symptoms I've read of people that have taken this it's actually scary worth reading up before you take something new."

1 / 10
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19 Report
  • Natas...
  • Taken for less than 1 month
  • February 20, 2024

"I got prescribed the medication for a really bad UTI, and I was so terrified to start them. I kept reading so many bad reviews of other people with really bad side effects. I delayed my prescription for like 2 days until the pain got so bad I just took them. It’s day 2 now of a 3-day course, and I honestly feel great! My pain started going down within the first 12 hours after taking the first pill. I've had zero side effects. I’m so happy it worked for me, and it might also work for you! The benefits far outweigh the risks. If I hadn’t started my course, then I probably would’ve ended up in the hospital. Don’t let the comments freak you out!"

10 / 10
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3 Report
  • Shazz
  • Taken for less than 1 month
  • August 18, 2019

"Took this medication (trimethoprim) for UTI. Never again. Had a burning sensation in my stomach and awful pains. I was trembling and had the worst headache on day two that lasted all day. Nothing would shift it. By day three I was so fatigued I could barely move. Should have stopped this tablet on day 1"

3 / 10
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18 Report
  • greyl...
  • Taken for less than 1 month
  • October 3, 2018

"After taking two tablets I went into anaphylatic shock, had to call paramedics inject adrenaline and spend 18 hours in Accident and Emergency, just beware of this, I had never taken Trimehtoprim before, dangerous drug."

1 / 10
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20 Report
  • Denise
  • Taken for less than 1 month
  • August 29, 2021

"My GP gave me 3 tablets of Trimethoprim Mylan . I wish I had never taken them the side effects are not worth it !! The headache was so bad it just didn’t go away unable to do anything, constant nausea and chills and shaking . I cannot believe they can market this drug without extreme warnings . There was no pamphlet inside to notify of side effects. I am deeply upset about this and I won’t ever touch it again. I am not exaggerating Thank you"

1 / 10
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12 Report
  • Jodylou
  • Taken for less than 1 month
  • August 6, 2021

"Prescribed 1 Trimethoprim at night for a long-term UTI and all it has done is made the UTI symptoms worse. I'm fine in the day but at night I can't sleep because of the burning /tingling sensation in my girly bits, the pain is indescribable, I'm seeing my GP today so I'll get them changed. Worst antibiotic I've ever had."

1 / 10
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  • Chez
  • Taken for less than 1 month
  • September 28, 2019

"I had a UTI and was prescribed Alprim (trimethoprim), 300mg one at night. On the third day I developed a severe rash on both lower legs and feet. I have taken it for 5 days and I am not taking the last two. I have taken photos to show my Doctor, definitely seems like an allergic reaction of some type"

2 / 10
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16 Report
  • JB63
  • Taken for less than 1 month
  • November 25, 2016

"Cleared up the uti BUT 5 weeks after taking the final tablet I'm still having side effects. First noticed that I had a sore throat and stiff neck after taking tablets for 5 days ( was given a seven day course) but did not make connection with taking antibiotics. Continued to take medication. I then developed sensitive scalp, neck pain got worse and on and off headaches plus shoulder/back pain. Felt awful. I was on holiday at the time and it seemed to ease after about a week. Reported to my GP on returning to the UK. Now 5 weeks later, on holidays again, neck pain, sore skin, head pains are all back. Hope this helps others. Not sure if I should seek medical attention or just hope problems go with time."

1 / 10
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22 Report
  • DamnUTI
  • May 13, 2020

"Was prescribed trimethoprim for medium grade UTI that Ural & Hiprex couldn’t quite clear. 1 x 300mg for 7 days, 1st day I took two tablets. UTI has NOT gone away & seems to be getting worse again. Feeling fatigued and exhausted on this drug too, also off’ psychologically. This is the 3rd time I’ve taken it, belatedly remember that last time didn’t work too & I went back to a female dr who prescribed another round BUT ALSO wrote a penicillin script “in case it still doesn’t clear up”, which all UTI prone females know does the job. I ended up ditching the trimethprim & took the penicillin instead, which worked. My opinion as a 37 yr old female: refuse trimethoprim If you’re not allergic to penicillin. It doesn’t seem to be effective in the one 300mg/day dose against UTIs, & the side effects alone on that amount are crappy. I’d rather a dose of thrush & the UTI efficiently gotten rid than the side effects of this drug & the damn UTI STILL NOT cleared up."

1 / 10
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  • Edwina
  • Taken for less than 1 month
  • March 20, 2018

"I’m on a 3-day course with these tablets for a UTI Since taking them I’ve had the worst throbbing headaches, I’m dehydrated and can’t seem to quench my thirst, I’m exhausted (really fatigued) I have stiff neck and a sore throat. I’ve taken these in the past and never had side effects like this. They have changed somehow"

4 / 10
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19 Report
  • Molly
  • Taken for less than 1 month
  • November 10, 2019

"trimethoprim worked fine 2 months ago but got another UTI and was given 3 days of treatment while waiting for hospital culture to be done. trimethoprim makes me very very tired and bad depression and just no appetite. Only one more day to go so hopefully my appetite will pick up when dose over"

5 / 10
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15 Report
  • Female...
  • Taken for less than 1 month
  • March 21, 2022

"This antibiotic has left me really unwell, I was prescribed 200mg 2x daily for 3 days, I only took 3 tablets ( 1 a day)..firstly felt like my kidneys had been battered, followed by severe stomach pain, extreme shivers and anxiety, also bad insomnia !! Getting sharp shooting pains ( like an electric shock all through my body !! Bad muscle aches as well.. warning !! If you suffer mental illness please avoid, as these pills really heighten everything. No more for me, it is an awful drugs. Not forgetting head aches, facial pain and horrendous nausea. I feel for all the patients experiencing these unwanted side effects, it's been 1 and a 1/2 days since stopping them, praying this will all pass real soon. In my opinion, they should be taken off the market pronto hope doctors realise what toxicity they cause. I never will I take these again, not worth the suffering."

1 / 10
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9 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.