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Trimethoprim for Bladder Infection User Reviews

Brand names: Primsol

Rating: 3.3

Trimethoprim has an average rating of 3.3 out of 10 from a total of 34 reviews for the treatment of bladder infection. 15% of reviewers reported a positive experience, while 71% reported a negative experience.

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9%
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Reviews for Trimethoprim

Commonly mentioned side effects
  • Dhf...
  • October 27, 2018

"I had other antibiotics before and other medicines, but never had side effects or allergies till I was prescribed trimethoprim. Took 1 tablet, and after a few hours, I started to have a headache-not that painful, but after the second tablet, it was really bad. I woke up during that night. The next morning, the headache was better, and I thought I should take another tablet to see how I feel. I had it with food to be sure I wouldn't be sick. I regretted it after 1 hour or so when suddenly I got nausea, a bad taste in my mouth, and the worst throbbing headache ever! Couldn't do anything, just stayed in bed. Eventually, I started to feel better and stopped taking these. Reading other opinions on here, I think they should ban this antibiotic."

1 / 10
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32 Report
  • Bay...
  • Taken for less than 1 month
  • June 3, 2019

"Took this antibiotic many times and never put two and two together that the bad tummy and headache, sore throat was the tablets. The last time I took them, I had salmon pink skin, rash, swollen eyes and lips, and diarrhea. Was rushed to the hospital in an ambulance. Would suspect if I took again it would be anaphylaxis. Steering well clear of this awful drug."

1 / 10
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28 Report
  • Lee...
  • Taken for less than 1 month
  • August 16, 2019

"Cystitis infection and prescribed these trimethoprim tablets. Took the full course and feel totally exhausted, difficulty sleeping, anxious. Infection still hasn't totally cleared up! Will NEVER take these pills again. SHOCKING."

1 / 10
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20 Report

Frequently asked questions

  • Sta...
  • Taken for less than 1 month
  • April 17, 2023

"As I sit here with a UTI and wait to phone the GP in the morning for antibiotics, I suddenly remembered how ill I became on trimethoprim two years ago. Reading these comments, I didn't realize how many people have had bad experiences with this drug. The first thing I'll say to the doctor is, 'Don't ever give me trimethoprim again, EVER!' On day 3, I had to have an out-of-hours doctor come to visit me. I was so unwell. I was involuntarily violently shaking, I had pain throughout my whole body, the worst pain in my head, and felt like I had the flu. It was the tremors and shaking that were terrifying. The doctor told me to stop taking them immediately, and thankfully, after three days, I started to slowly improve. Never again! I'm not sure what my other options are for a UTI, as there's another antibiotic that I'm allergic to."

1 / 10
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8 Report
  • rad...
  • Taken for less than 1 month
  • February 8, 2020

"I am currently on day 2 of trimethoprim. The 1st day after taking it, I had slight nausea and felt very drowsy, almost fell asleep in my class, but I also walked a lot that day. Took one this morning, fell asleep an hour or so after, but no nausea today. I had a really annoying UTI/bladder infection. I've never taken an antibiotic before, but I really don't want that damn infection coming back because it sucks. Pro tip: If you have an infection, see a doctor ASAP. Don't wait or use over-the-counter stuff. Thought mine had gone, a week later it was back."

7 / 10
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17 Report

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  • Ala...
  • December 11, 2020

"I wish I had seen these comments before I took Trimethoprim, which was several years ago now. It affected me really quickly too, and within about an hour, I also experienced negative effects from this drug. Never again! High anxiety and random thoughts. Had to keep the light on all night as I was so afraid. Extremely fatigued and depressed too. Senses heightened greatly, and at times had sudden surges of energy doing bizarre things. Thought I was having some sort of breakdown. Took it for a few days and then stopped. It left me feeling awful for several days. Put on another drug which worked well on the infection without such negative side effects."

1 / 10
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14 Report
  • Nan...
  • August 9, 2015

"I took the 200 mg strength and was given 16 tablets. On the morning in which I took the very last dose, I came out in the most horrendous rash I have ever experienced and have been told I must never take that drug again. The rash, over a period of about 3 hours, spread over my entire body, including my face. I was hot and itchy beyond belief. My doctor was absolutely shocked, as she said that any reaction usually appears after taking just a few tablets. I'm in the U.K., so some questions are not relevant to me."

3 / 10
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22 Report
  • Reb...
  • Taken for less than 1 month
  • March 31, 2023

"I was prescribed this drug for a bladder infection. Within an hour of taking it, I had one of the worst headaches I've had since my last migraine. It was the intensity of a migraine, I tried paracetamol and ibuprofen, but nothing touched it. I've got horrible anxiety, I feel shaky, and my stomach feels truly awful. I feel sick and have no appetite. I also feel exhausted, I didn't sleep well last night due to racing thoughts. Much of what others have described has been my experience. I'm currently waiting for a call from my GP surgery for a different antibiotic. Take the advice on here: don't take it, it's a truly awful drug. It should be taken off the market!"

1 / 10
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6 Report
  • Thi...
  • November 30, 2020

"Bladder infection. Almost an hour later, I had severe dizziness, hot flashes, extreme anxiety, and felt like my blood pressure had dropped drastically. The next 3 days, I had a horrible headache, nausea, the worst fatigue ever, completely no appetite, and severe anxiety. Kidneys were very painful, hard to breathe without exacerbating the pain. On the 4th night, I experienced all that and insomnia/strange random thoughts at night that seemed to have a mind of their own. Day 5, I feel much more like myself but still delicate. I notified my doctor and NHs24 about my symptoms, and they said to keep taking it! Glad I did because I am feeling much better now. Look up 'bacteria die-off symptoms', this may be what we have been experiencing. Harmful endotoxins from the dead bacteria in our systems due to antibiotics. I've read the worse you feel during die-off, the more you needed it. Take a good probiotic at night to ease symptoms."

6 / 10
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9 Report
  • Maz...
  • Taken for less than 1 month
  • May 8, 2020

"I had severe cramp from the neck downwards. I couldn't sit, stand, or lie down. It was so severe. I stopped taking it and went to the doctor. It started easing off but was still there after a day. The doctor said it wasn't the Alprim and I should continue. So I restarted the medication, and it cranked up again in all its severity. It was awful, so I stopped, and the cramp went away."

1 / 10
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10 Report
  • lad...
  • March 8, 2016

"Due to allergies, trimethoprim is the best choice for a bladder infection for me. Used once before, about 4 years ago, after infection from a catheter after surgery. Works fine for me, and I have not had the side effects some experience. So, in my case, a very good choice."

10 / 10
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16 Report
  • Anonymous
  • Taken for less than 1 month
  • April 3, 2015

"I was prescribed 200 mg 2x a day, and two days in I stopped taking these tablets - that was two days ago, and still, my entire body is a mass of burning red itchiness - looks like measles and is getting worse."

1 / 10
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15 Report
  • Pan...
  • Taken for less than 1 month
  • August 29, 2022

"Oh my God, absolutely awful stuff. I've had anxiety for years, so I know my body and panic attacks, etc. Day 5 of these, and my manager had to call 999 as I genuinely thought I was dying. The MOST intense panic attack I've ever had. Heart thumping through my chest, faint, head spinning, hands and legs numb, weak... this was all after days of constant anxiety and dizziness. I've come off them and am still feeling dizzy, but hoping they'll wear off soon. Never again!!!!!"

1 / 10
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4 Report
  • Haz...
  • Taken for less than 1 month
  • April 13, 2021

"Was prescribed this for a UTI, made me so ill, nausea, terrible constant headache, upset stomach, sweats, chills. I never slept when on them, had weird dreams, and made me anxious. I will never take again and would just rather suffer with the UTI."

1 / 10
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5 Report
  • Lee...
  • Taken for less than 1 month
  • April 7, 2023

"I have already taken a full course of antibiotics, and the UTI did not clear. The doctor then prescribed 2 x 200 mg daily of trimethoprim. I have taken 4 (2 days), and last night I got a really bad itch across the bridge of my feet, and I could have clawed them off! I've been feeling nauseous and not great at night, restless. I don't think I will be taking these again. However, the UTI symptoms have eased slightly."

7 / 10
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2 Report
  • Fre...
  • Taken for less than 1 month
  • April 27, 2021

"I had similar experiences as previously reported after 3 tablets: vomiting, weakness in legs, no appetite, and wanting to sleep all the time. The doctor has now changed the antibiotic, and hopefully it works."

2 / 10
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2 Report
  • Anonymous
  • Taken for less than 1 month
  • July 22, 2021

"I feel really, really terrible. The UTI may be preferable, but on the positive side, it is very effective for weight loss, as I can't bear the sight or smell of food. For the first time in my life, I may cut the recommended treatment short. It did get rid of the UTI, though."

2 / 10
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2 Report
  • Fox...
  • Taken for less than 1 month
  • April 19, 2021

"Desperate have read comments which leads me to believe trimethoprim might be making me feel so dreadful. I have prostatitis and have just done my 3rd week on this drug, having been on ciprofloxacin for 10 days prior to the trimethoprim (changed due to possible tendon problems taking ciprofloxacin). I became constipated within 2 days, tried to tough it out with a combination of laxatives, but just feel dragged down, very anxious, morbid thoughts, no energy, and now shaky and worried about the persistent pain. I hope this is the cause of my problems others have intimated, so that if I stop it, these problems will go away."

1 / 10
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2 Report
  • Son...
  • Taken for less than 1 month
  • April 14, 2021

"I actually was given this for prostatitis. The first course I was prescribed had no side effects, but the next time one 200 mg tablet gave me a very painful headache that I could not get rid of using paracetamol, ibuprofen, or cocodamol. The headache lasted for four days. Strange that the first course was fine but not the next."

3 / 10
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1 Report
  • Sic...
  • Taken for less than 1 month
  • May 5, 2021

"Started taking this antibiotic for 5 days, twice a day, and the bladder infection is still here. Antibiotic resistant. Yes, there were side effects, but nothing too bad. Headache, some nausea, but manageable. On a different antibiotic now, penicillin, so fingers crossed it works."

6 / 10
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  • Ohm...
  • Taken for 1 to 6 months
  • August 2, 2024

"I have taken this medication twice in 3 months, and I would not go off all these negative reviews. For me, it caused itchy skin, but I solved this by taking an antihistamine, which solved it. I was so scared taking the medication from all the bad reviews on here. Everyone is different, and you cannot go off other people's experience. I could not wait to finish the medication, as every day I was filled with anxiety and fear from knowing what side effects this medication can cause. Nothing bad really happened, but my UTI came back, and now I am on stronger antibiotics, which have worse effects than this antibiotic."

9 / 10
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1 Report
  • Jsy...
  • Taken for less than 1 month
  • December 10, 2012

"It cleared my cystitis, but I got a rash after 4 days, so stopped it."

5 / 10
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32 Report
  • Bla...
  • September 2, 2020

"I've taken trimethoprim for two days for a bladder infection and seem to have every side effect, and I've still got the bladder infection, I would not accept these pills again."

1 / 10
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10 Report
  • Fif...
  • Taken for less than 1 month
  • August 18, 2021

"Never ever will take these again! Panic attacks, shaking, feeling anxious, depressed, awful."

1 / 10
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8 Report
  • Anonymous
  • Taken for less than 1 month
  • April 23, 2022

"After 1 dose. Itching all over legs, feeling nauseous, sleepy all day, extreme fatigue and headache, pain in abdomen. Didn’t take the 2nd dose. Tell me another easy way to get rid of the infection."

1 / 10
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5 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.