Tranylcypromine and Drowsiness: What Users Say

• dor...
• Taken for 6 months to 1 year
• March 16, 2019

Tranylcypromine for Depression "The granddaddy of antidepressants. The first couple of months or so on Parnate will be a little rough since it tends to sedate you during the day and keep you up at night, but this effect usually diminishes with time. As echoed by people here, the diet is pretty overstated. There are very few foods that will actually cause a hypertensive crisis. You will be fine as long as you don't binge on fancy cheeses, cured meats, or eat spoiled food. Not a lot of doctors know this, but you can also combine it with TCAs and stimulants if it doesn't completely resolve your depression on its own. Probably the best option you have for hard-to-treat depression at the moment."

• Anonymous
• Taken for 2 to 5 years
• January 4, 2014

Tranylcypromine for Depression "Parnate is a great medicine. It will mess with your sleep cycle and cause severe insomnia, but other than that, it's great. It improves mood, lowers anxiety (not perfectly, but enough), improves sex drive, and gives you energy. In my case, I welcomed slight weight loss. I've taken up to 40 mg a day. It's very important to take Parnate either in the morning or at 2 pm. If taken in the morning, it may cause drowsiness at around 2 pm. Take food warnings seriously. If I eat the wrong food, my blood pressure definitely increases."

• dan...
• Taken for 1 to 6 months
• May 25, 2018

Tranylcypromine for Depression "I have kind of atypical depression. This drug is the ONLY true antidepressant on the market. I have tried nearly all ADs, even Nardil didn't work for me. Parnate works fast and keeps working as long as you take it at the right dose and time. I can just stop and go back on this drug smoothly without side effects (maybe just some sleepiness after taking the pills). It may change your life. The only bad thing about Parnate is that it's expensive (2 bottles). Food interactions are a joke for me, I can eat whatever without a problem, but everyone is different, so follow your doctor's instructions."

• Alb...
• Taken for 1 to 6 months
• March 20, 2013

For Depression "After a hospitalization where no net good came about, I changed psychiatrists. The new guy is semi-retired, only works two half days a week - but is extremely familiar with MAOIs and one of the few doctors in a state of 4 million that will prescribe them. My symptoms were more refractory and atypical depression, and it's been quite a journey to try and work something out. I've been on tranylcypromine for 3 months now. As it's an analog of amphetamine, my major side effects have been similar to amphetamine - sleeplessness (3 hours a night), hyperalertness, agitation when the dose wears off (sucks as it's only 3 hours or so), and when really worn out it keeps going and I feel alert but make judgment errors. Depression is gone though!"