Skip to main content

Tapentadol User Reviews & Ratings (Page 3)

Brand names: Nucynta, Nucynta ER

Tapentadol has an average rating of 6.2 out of 10 from a total of 423 reviews on Drugs.com. 53% of reviewers reported a positive experience, while 29% reported a negative experience.

Reviews for Tapentadol

  • PaddyO...
  • October 24, 2013

Nucynta (tapentadol) for Pain "My Pain mgt. doctor switched me from Demerol to Nucynta for break-through pain of chronic migraines. Surprisingly, I found it to be effective, but I noticed from the start that it greatly diminished my language skills: reading, writing, and speaking. As per doctor's orders I stayed in bed while under the effects of Nucynta so this weird side effect didn't cause me any issues. Until...After using it for 15 months, I found my language skills to be extremely loopy, creating comments from friends and neighbors, DAYS after taking Nucynta. That scared me and my doctor immediately took me off this medicine when I finally advised her of the language problem it presented. I could be reading a sentence and forget a word's meaning."

9 / 10
Was this helpful?YesNo
77 Report
  • Peaches
  • Taken for less than 1 month
  • May 31, 2019

Nucynta (tapentadol) for Pain "Nucynta is the worst! I've suffered from chronic pain for years & have tried many different pain meds. Long-acting, short-acting, brand, generic, tabs, caps, patch, etc, but nothing I've tried has EVER made me feel as lousy as Nucynta! Nausea, fatigue, dizziness, headache, & achy. It didn't suppress my pain the way I had expected it to considering it cost $1071.69 for 120 tabs! Thank goodness my ded was met so it cost me $0, but I'm feeling some kinda way about my ins paying this much $ for something so useless & ineffective!! I feel a refund is in order! I'd much rather go back to my Percocet 10mg × 4/day which was WAY more effective & less expensive! If you're prescribed this drug & are unable to tolerate it, be sure to have a standby available! Plus, this drug is NOT readily available at any pharmacy & has to be ordered. A p/a from the insurance is required & there is NO generic equivalent. Kudos to those Nucynta IR provides even minimal relief, and CONGRATS to those it actually works well for!"

2 / 10
Was this helpful?YesNo
44 Report
  • graci...
  • Taken for 6 months to 1 year
  • October 10, 2014

Nucynta ER (tapentadol) for Pain "I could not deal with the side effects of Oxycontin or hydrocodone. Too much dizziness and severe itching. Unable to get restful sleep. Nucynta ER 50 2 times a day has been MUCH better for me. Very little side effects and only for the first couple of weeks. I sleep better too. Only objection is that it wears off after only about 5 hours. So I have to take hydrocodone occasionally."

8 / 10
Was this helpful?YesNo
71 Report
  • Rick...
  • Taken for 6 months to 1 year
  • June 16, 2015

Nucynta ER (tapentadol) for Pain "I have been taking this medication for the better part of a year now in ever increasing doses until reaching the maximum dose of 250mg 2X daily. I have found it does a good job of controlling what I refer to as "lesser" pains. I find general movement is easier, minor physical activities such as walking, driving, showering etc. are less painful. However, it does not do as much for the more "major" pains. More active physical activity such as gardening, house cleaning, etc. are still painful, however the pain is "masked" by the drug and I "pay" for these things later..I have had chronic pain for over 30 years and I do not expect anything will ever make me 100% again, but this drug has made me able to enjoy a few hours a day of comfort"

6 / 10
Was this helpful?YesNo
67 Report
  • CNB
  • Taken for 2 to 5 years
  • September 18, 2013

Nucynta (tapentadol) for Pain "I have been on the same dose of tapentadol and tramadol for 2 years for atypical trigeminal neuralgia with no development of tolerance. Limited gastrointestinal side effects and no CNS side effects. The medication has not lost any efficacy and has been more effective for my pain than Duragesic (fentanyl) 25mcg patches. With the Nucynta savings program I pay only $25 a month for 120 tablets."

10 / 10
Was this helpful?YesNo
76 Report

Are you taking this medicine?

  • Mommab
  • Taken for less than 1 month
  • June 10, 2019

Nucynta (tapentadol) for Pain "My doctor put me on Nucynta 50 mg 2x day for pain. I still have the back pain and no relief, it did however, make me sleep for 30+ hours, make me sick to my stomach, gave me diarrhea and did not help. I took this Saturday night at 11:00 pm. It is now Monday morning 11:30 am, and I just want to sleep. I have no appetite. I haven’t eaten anything since 5:00 pm Saturday and I’m still not hungry. This medicine is the WORST."

1 / 10
Was this helpful?YesNo
43 Report
  • Pt se...
  • June 11, 2014

Nucynta (tapentadol) for Pain "Tapentadol 50mg four times a day when required for pain . Before Nucynta I was taking Opana IR as well as extended release formula usually alternating the two every couple of months. Pain relief is controlled best by Opana for me personally. However several side effects have required a change so Nucynta was chosen. Works great no freaky side effects and less intoxicating effects. "

7 / 10
Was this helpful?YesNo
72 Report
  • d91689
  • February 26, 2016

Nucynta (tapentadol) for Pain "I got nucynta after I had surgery on my hand. I severed tendons and the recovery was awful. I was given Norco and then also nucynta. The 2nd night I took the nucynta I started to feel strange. My heart was racing and I felt panicky. My bf asked me if I was okay and I couldn't answer him. I stared at him because I was trying to not have a panic attack. The feeling I felt is hard to explain. I just knew something was wrong and I was having some kind of reaction. Finally I asked him to take me to hospital. Once on the freeway I had a hallucination. I saw a 20 ft tall figure on the side of the road. I swear on my life. No other drugs were involved.. I don't drink and have never had this happen before. I was okay a few hrs later but it was scary!"

1 / 10
Was this helpful?YesNo
62 Report
  • amsterl
  • August 16, 2014

Nucynta (tapentadol) for Pain "I have acute sciatica and have been taking Percocet 10mg along with tramadol 4x day. I was getting concerned about the acetaminophen so I asked my doctor for Nucynta. I was prescribed 50mg along with the tramadol but I had gotten no pain relief. Then started taking 100mg but the pain is still very noticeable. For me, the Percocet seem to do a better job of pain relief."

5 / 10
Was this helpful?YesNo
70 Report
  • dimples
  • Taken for 5 to 10 years
  • October 23, 2018

Nucynta (tapentadol) for Pain "This is the most dangerous drug on the market I was on it for ten years ninety pills a month and still needed more. I was told by doctor it was non addictive. I have written letters to the FDA and I am going to my congress man to try and get this drug pulled from the shelf. I nearly died when I came off with all the withdrawal effects. Stay well away and please write to FDA so that the drug companies stop making profit from this drug."

1 / 10
Was this helpful?YesNo
46 Report
  • Cinny
  • February 11, 2013

Nucynta (tapentadol) for Pain "I have been on Nucynta for 1 1/2 yrs. I've had major problems with pain meds. Vomiting, not sleeping to very high liver counts. I've had 4 surgeries on my wrist in 3 yrs. 1 being a internal amputation of the ulna hump & approx 3" of bone. Picture that hump in your wrist & 3" of the bone that is attached to it gone. Bone hitting bone, pain I wouldn't wish on anyone. My PM put me on 50mg x 2-4 times a day. For the 1st time in 14 yrs I'm almost pain free. I'm going this week to have the dosage increased. I had to stop working and I never thought that I would have a normal life or be able to hold my grand kids. Now I have 6 grand kids and I spend everyday with them. I can even pick them up and hold them. My newest is 8wks old. Nucynta saved me."

9 / 10
Was this helpful?YesNo
77 Report
  • Lady...
  • February 10, 2010

Nucynta (tapentadol) for Pain "Nucynta has worked very well for all my aches and pain, from the most severe to those I didn't even know I had. At first, it did make me groggy which was a problem, but I kept taking it anyway because it did take away most of my pain. After a couple of months of use, it takes away my pain, just like it did at the beginning, but I no longer feel sleepy. I feel energetic, happier and am able very active because I hardly feel any pain. I highly recommend it, but you do have to give it a chance because once your body adapts to it, the adverse effects far outweigh the benefits."

10 / 10
Was this helpful?YesNo
91 Report
  • Roscoe
  • March 2, 2014

Nucynta (tapentadol) for Pain "After taking second pill had to go to E.R. I couldn't control my emotions I broke down balling like a baby no reason why just uncontrollable need to cry. Never had these side effects with opiate pain relievers. "

1 / 10
Was this helpful?YesNo
71 Report
  • Major...
  • June 24, 2019

Nucynta (tapentadol) for Pain "I am on a trial of Nucynta medication 50mg every 6 hours. I have been on several different pain medications and lately they have not been working due to a worsening condition. I have fibromyalgia, DDD (degenerative disc disease) and arthritis in my cervical and lumbar spine as well as a tumor that caused me to have a near total mandibulectomy which is now the main source of my pain. The first few days I felt very dizzy but surprisingly my pain level is so much better I cannot believe it! I hope this continues. The only downside is the cost. My co-pay was $53 dollars and that was for 7 days worth! If this works then I have to pay another $53 dollars!! So this works for me but the cost does not so I am not sure how this will all work out."

8 / 10
Was this helpful?YesNo
41 Report
  • Steve
  • Taken for 1 to 2 years
  • September 3, 2018

Nucynta (tapentadol) for Pain "On 50mg three times a day for 2 years. I took it to treat Reflex Sympathetic Dystrophy also known as Complex Regional Pain Syndrome. Tolerated well and it seemed to help a little, just enough to take the edge off the pain. After two years it stopped working so the dose was increased to 75mg 3x a day which caused the side effect of Serotonin Syndrome. I had to be hospitalized and almost died extreme acute hypertension! Almost a year later and still suffering from the incident. It ruined my life. Be extremely careful! My Doctor will not Rx it anymore for any of his patients because of the severity of adverse side effects he has witnessed in some of his patients. And if your Doctor does increase your dose or add a new drug check for interactions in case they don't know."

Was this helpful?YesNo
46 Report
  • half...
  • Taken for less than 1 month
  • November 12, 2013

Nucynta (tapentadol) for Pain "I'm taking 75 mg qid,or severe spinal degeneration as well as other issues. In the past I used dilaudid, percocet, and m.s. contin. Works great for pain but I am more tired than with other drugs. My insurance company denied approval, so I faxed them a letter explaining why I needed it and they approved it 10 minutes after the fax was sent. Thank God !!"

9 / 10
Was this helpful?YesNo
72 Report
  • Cockf...
  • September 7, 2015

Nucynta (tapentadol) for Pain "I Have a cyst along my spine with a messed up disc. The codeine based medicines side effects were terrible. Nucynta 75mg. 3 X day works wonders. I only take it when I do a lot of work which affects my lower back. My wife likes me to take it as I am not as grumpy. Like all medicines some work for certain people and not for others. For me Nucynta and Demoral work best with min. side effects"

9 / 10
Was this helpful?YesNo
61 Report
  • kadee...
  • Taken for less than 1 month
  • March 24, 2016

Nucynta (tapentadol) for Pain "I was prescribed this medication because I'm allergic to some of the more common pain killers. I took it a total of 2 weeks, daily as prescribed. I had horrible hallucinations became severely depressed, had insomnia and I felt like every ounce of joy was sucked out of my body. I had the strangest experiences with this medication. I felt like I left my body. Once, I saw myself jumping off the balcony. I was clearly hallucinating. It was the worst experience from a medication I've ever had. I was extremely distraught but, had no idea why. My husband freaked out and rushed me to the doctor. I was told that it was side effects of the medication. I had to be weaned off of it by a dr. Even under the Dr's care, I had horrible withdrawal sympto"

1 / 10
Was this helpful?YesNo
58 Report
  • Bec
  • Taken for 1 to 2 years
  • February 3, 2019

Nucynta ER (tapentadol) for Pain "This medicine has been such a blessing for me. Felt as if my quality of life was completely lost from chronic pain. Multiple spinal issues and 3 surgeries later I was left with terrible neuropathy and pain all down my right side. This did the trick. Now I have my life back!"

10 / 10
Was this helpful?YesNo
42 Report
  • Lulumom
  • Taken for 1 to 6 months
  • December 13, 2016

Nucynta ER (tapentadol) for Pain "I have 4 slipped discs and a self fusing spine and I'm only 36. I have terrible OA in my spine that's hereditary. I failed epidural injections. The nerve pain kept me in bed crying most days and I couldn't be a wife or mom. I started on Norco, then moved to Ocycodone. They added neurontin and nothing took care of the burning shooting pain that was at the base of my skull and down my left arm. I got interminent relief for one year. I changed doctors and they put me on Nucynta ER 250mg once a day! I can honestly say I am pain free. I only take this and an anti inflammatory. I will say the consistent side effect is Nausea Vomiting and no appetite. I don't mind it as I'm finally pain free and I just eat small meals!"

9 / 10
Was this helpful?YesNo
54 Report
  • jgarr...
  • April 2, 2010

Nucynta (tapentadol) for Pain "I have only been taking Nucynta for about a week. It was prescribed to me for severe pain caused by nerve regeneration in my lumbar and sacral joints. I have been very close to being completely pain free thanks to my Doctor's willingness to try this medicine. The only draw backs I've had was pounding headaches the first couple of days. Through God's help and the right medicines, I'm feeling much better"

8 / 10
Was this helpful?YesNo
86 Report
  • Miblu...
  • May 20, 2014

Nucynta (tapentadol) for Pain "After orthopedic foot surgery I was prescribed Percocet. After side effects my medication was changed to Nucynta. For me, I prefer the Nucynta. My problems with constipation went away immediately. I had a little itchiness from Nucynta, but nothing I couldn't tolerate. I got much better pain relief from the Nucynta too. Good thing I have insurance as it's very pricy."

10 / 10
Was this helpful?YesNo
66 Report
  • hardhat...
  • December 8, 2009

Nucynta (tapentadol) for Pain "My doctor put me on Nucynta for lower back pain because I told him tabs are taking over my life and to addictive. He said try this medicine and see if you like it. It's less addictive. It takes care of the pain for about one hour but makes me sleepy so I can't take them at work. Tablets made me not only work more comfortable but feel good to. So if you want to try it just remember its not like Lortabs or Percocets."

6 / 10
Was this helpful?YesNo
86 Report
  • Pain...
  • November 20, 2015

Nucynta ER (tapentadol) for Pain "In 2012, I was in an accident. As a result, I have had 4 surg to my right wrist. I then developed bi-lateral epicondylitis, trigger finger, and myofascial pain syndrome. I have taken a variety of meds without relief. I wasn't able to participate in life or carryout routine tasks. My pain specialist prescribed Nucynta ER 50mg @ 1 tab twice a day (morning & evening. I was also prescribed Nucynta IR 50 mg @ 1-2 tabs up to 4 times per day. The Nucynta ER lowers my pain throughout the day. If I have housework, etc, I can take 1 to 2 Nucynta IR prior to starting the tasks. This gives me the extra relief I need to complete the work. If my pain spikes, I can also take the IR. Nucynta has given me my life back."

8 / 10
Was this helpful?YesNo
58 Report
  • Anonymous
  • May 6, 2012

Nucynta ER (tapentadol) for Pain "This is great base/stable medication. I take it twice a day and have other medication for break through pain. I had 2 back surgeries and 20-30 epidurals. I'm young (less than 40). It is not cheap, but I find it worth the price. I am a lawyer and need to be quick on my feet. This medication does not weigh me down mentally."

10 / 10
Was this helpful?YesNo
75 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.