Tapentadol Alternatives Compared
| Tapentadol | Tramadol | Gabapentin |
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| Tapentadol | Tramadol | Gabapentin |
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Prescription only
Prescribed for Pain, Diabetic Peripheral Neuropathy. Tapentadol may also be used for purposes not listed in this medication guide. |
Prescription only
Tramadol is a strong opioid pain relieving medication that may be used to treat moderate to severe general and nerve-related pain. Tramadol may be habit-forming and misuse can cause addiction... View more |
Prescription only
Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may... View more |
Related suggestions Popular comparisons
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| More about Tapentadol | More about Tramadol | More about Gabapentin | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Tapentadol has an average rating of 6.3 out of 10 from a total of 426 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 29% reported a negative effect. |
Tramadol has an average rating of 7.0 out of 10 from a total of 1862 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 24% reported a negative effect. |
Gabapentin has an average rating of 7.2 out of 10 from a total of 2554 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Tramadol prices |
View all Gabapentin prices |
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| Dosage Forms Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Nucynta, Nucynta ER | ConZip, Qdolo, Tramadol Hydrochloride ER | Fanatrex, Gabarone, Gralise, Neurontin | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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4 hours |
5.2 hours |
6 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 382 drugs are known to interact with Tapentadol:
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A total of 688 drugs are known to interact with Tramadol:
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A total of 270 drugs are known to interact with Gabapentin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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November 20, 2008 |
March 03, 1995 |
December 30, 1993 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.