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Bactrim DS for Bacterial Skin Infection User Reviews (Page 2)

Bactrim DS has an average rating of 4.2 out of 10 from a total of 56 reviews for the treatment of Bacterial Skin Infection. 23% of reviewers reported a positive experience, while 54% reported a negative experience.

Reviews for Bactrim DS

  • Kat
  • Taken for less than 1 month
  • July 8, 2019

"This was my first time taking Bactrim because I’m allergic to penicillin. I had a infection in my big toe due to an ingrown toenail. I give three stars because it did work to clear up the infection. However on day seven I began having severe reaction to the drug. Excruciating pain my feet knees and hips combined with head to toe rash and itching. I took Benadryl and prednisone and still took several days to go away. The stuff is horrible. The pain in my joints and lower leg bones was unbearable. Never again."

3 / 10
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  • Woooo...
  • Taken for less than 1 month
  • May 7, 2019

"So I had taken Bactrim before for a UTI and it was great, it cleared it up and I didn’t have any side effects. This time I'm on it for an abscess and it a whole different story. About 3 or 4 days in I couldn’t keep any food down and had EXTREME nausea and vomiting. Another 2 days go by and I can’t even keep down water or pills. I sleep maybe 3 or 4 hours a night and have a terrible headache for like a week. I go to the doctor yesterday and she tells me I have to keep taking them. I’m still dying"

3 / 10
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  • Anonymous
  • June 2, 2011

"I was prescribed Bactrim 2x a day for 30 days, for Staph Infection. However, after taking it for about 7 days, I developed a rash. The rash did not itch, but started at my shoulders and went down to legs. I've now begun taking Benadryl to counteract symptoms. So far, it hasn't helped, rash still there. As far as the Staph infection, it looks a lot better."

7 / 10
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20 Report

Frequently asked questions

  • Disap...
  • Taken for less than 1 month
  • August 17, 2020

"I got a skin infection from a spider bite, so prescribed Bactrim. Relatively mild side effects except for sometimes feeling stoned. After my last dose (after 10 days), I experienced the worst side effects, I felt high, nauseous, exhausted, depressed, overly worried, my urination speed decreased, my urine was unusually dark despite drinking tons of water, had chest pains, a cough (note, I also have asthma), a severe headache that lasted over one day, and I felt sick in general. Never taking this again, at this point, it's unbearable and there's nothing more I can do right now other than wait it out"

1 / 10
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  • daisys...
  • February 9, 2015

"I have a large swollen infection believed to be staph infection. This medicine is working well but day 2 I am so nauseous even after taking Zofran 8mg I can not bare the thought of swallowing it or anything else. I've taken this before and did not get this effect. I have many other health issues at the time but I was shocked I reacted this way."

8 / 10
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Are you taking this medicine?

  • canada
  • May 3, 2015

"I have used this medicine. For a stap bacterial infection. Normally 9 years ago it would work rapidly and in 10 days it would be completely gone. But it has come back several times through the years. Now with this last infection I'm having to take double the dose, every 12 hours and I notice it is been hard it to get rid of. I'm hoping I won't get this skin boil again because I'm afraid of the antibiotics are not working 100%. What other options are there to take? But the bactrim is been my saver, til now"

8 / 10
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  • Alex
  • February 15, 2018

"Absolutely the worst medication I've ever been on, and I've been on a lot. If an alternative is offered, take the alternative. Intense thirst, super awful anxiety (borderline paranoia), stomachaches and heartburn out the wazoo, night sweats, rash, dizziness, joint pain, loss of appetite were my symptoms (amongst others). Doc switched me to clindamycin. Not a single side effect! Symptoms gradually got better after dropping Bactrim."

1 / 10
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  • Anonymous
  • February 10, 2018

"Never ever again will I take this medication. Ended up in ER with what they said was Cellulitis. Gave me Bactrim and Keflex to take. After taking the Bactrim just after one day headaches started. On day 4 I woke up and could not move any of my body as every muscle, joint, neck and head was so sore and aching. Went straight to urgent care and they took me off the antibiotics. Still having severe pains all over and I'm hoping it's just because the medication is still in my system. Seriously do not take this. There are plenty more antibiotics to take than this and going through this also."

1 / 10
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  • Abbie
  • Taken for less than 1 month
  • May 30, 2019

"I developed a painful staph infection in my nose after a really nasty cold. Bactrim DS cleared it up quickly, but it was harsh on my body. The worst side effect that I had was extreme fatigue. Even walking around the house left me dizzy, out of breath and shaking with exhaustion. Luckily I had the sick days to take off work because I don't think I could have done it. I also had nausea and insomnia but that was mostly just inconvenient. The exhaustion though was debilitating. I finished the entire 10 course because the staph infection was painful and my nose was bright red and swollen. I was scared not to finish the meds. I would definitely ask for something else next time though."

2 / 10
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  • Kaino
  • Taken for less than 1 month
  • June 12, 2017

"I was prescribed Bactrim twice a day for 10 days. The first day was ok by 2nd day I had a bad case of nausea and itchy. 3rd day nausea, fatigue, flu like symptoms and feeling cold along with insomnia. I stopped taking it and gradually I'm feeling myself. I continued keflex until the infection healed. I won't take it again. It's not worth the misery in my opinion."

2 / 10
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  • HEE
  • Taken for less than 1 month
  • May 14, 2017

"I was prescribed this for a Staph infection of the Skin. The first few days I was very fatigued and had mild neck pain then on Day 7 of 10 that it was prescribed for I started breaking out in a rash on one thigh and then it spread throughout the day and was on my chest and arms by the night. I was also freezing! I took 2 benadryl that night then woke up the next morning and the rash all over from my neck all the way down to my ankles, front and back and was cold all day! I went to urgent care and ended up getting a steroid injection at urgent care then had to take a high dose Prednisone for 3 days after that. After Steroids were started I noticed that the joint pain went away and I also was swelled from the rash."

3 / 10
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  • Dante
  • Taken for less than 1 month
  • May 18, 2018

"Bactrim healed the abscess infection that I had, but the lethargy was absolutely crippling for me. The first day on it I was driving and was literally falling asleep for 2-3 seconds at a time and almost crashing. Had to go home obviously. Other than that I sides but even with caffeine my body felt like it weighed 1000 lbs and couldn’t keep my eyes open"

2 / 10
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  • Cece
  • Taken for less than 1 month
  • September 17, 2020

"My teen daughter was given 10 day course of Bactrim (and Keflex) for an infected bug bite even though she isn’t allergic to penicillin. It seemed to work until day 6 she had a mild fever and rash. Then on day 8, her face covered with rash and within half an hour of the first rash, her whole face ballooned and her lips, throat, nose were in pain. We rushed to ER and she had Benadryl in IV. It was scary and so I wondered why the doctor prescribed it if the majority of users have had terrible experiences with it (the ER doctor immediately recognized my daughter’s allergic reaction to Bactrim so it must have been quite a common thing!!!) I will make sure we will never have this again!"

2 / 10
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  • James
  • Taken for less than 1 month
  • August 4, 2021

"Male, 49 years of age. Took Bactrim DS 2X a day for 14 days. I took it for an infected boil on my back. Within 2 days the boil began shrinking and the infection began clearing up. Side effects for me were exhaustion and muscle weakness. During the second week I would become tired to the point of falling asleep just from taking a shower and getting dressed. My arms were so weak I could hardly lift a bag of groceries ( I can bench 200lbs). My legs were sore like I ran a marathon. All of this cleared up about 3 or 4 days after I finished taking them. Overall it was worth it for me."

8 / 10
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  • Moon
  • Taken for less than 1 month
  • September 8, 2019

"I was prescribed Bactrim DS for an infected callous between my toes. I am diabetic, and take Tramadol for Fybromyalgia, and take extra Potassium. All three were listed as serious drug interactions but the pharmacist assured me I would be ok. Three days in I was miserable. Headaches, exhaustion, nausea, and loss of appetite. And no my urine didn't change to orange. And I drank lots of water too. I finally had to discontinue it."

7 / 10
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  • Kat
  • Taken for less than 1 month
  • March 8, 2021

"Been on Bactrim DS due to a skin infection after surgery. I take 2 a day, 12 hours apart. It is helping a whole lot but, I am so tired and weak. When I eat it makes me want to vomit. Will be so glad when the script is gone!"

6 / 10
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  • Anonymous
  • Taken for less than 1 month
  • June 27, 2019

"Exactly 7 hours after taking 1 Bactrim (generic form) I threw up and had to visit the ER and receive my steroids through UV since I had a bad allergic reaction. What’s with this stuff it use to work now it’s hurting people"

1 / 10
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  • Pmc
  • Taken for less than 1 month
  • April 28, 2018

"It's definitely working but I'm taking a beating. Had a post surgery skin infection. First I took cephalexin but it did not fully go away. Now on bactrim, 2 pills in the morning and 2 at night. On day 4 felt the hardest . Also taking probiotics at bedtime to help the digestive system. Got to say this stuff punishes you. I don't feel like myself. Foggy all day, small periods of shakes. Dry tongue and mouth. Wiped me out. Can't wait to return to me."

8 / 10
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  • Janey
  • Taken for less than 1 month
  • February 16, 2020

"The skin infection is healing I think, so far been 4 days. I started taking Bactrim for wound not healing after plastic surgery looks healthier now but not healed. Raging headaches since started medication biggest thing is discharge and UTI that formed after I started. Side effects are horrible, I can barely walk due to the severity of the UTI. But it seems to be helping the wound- this is the 3rd time in the course of ten years ish I’ve taking Bactrim every time I get a UTI..."

9 / 10
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  • Anonymous
  • Taken for less than 1 month
  • September 27, 2020

"I am on my second day of Bactrim DS and about half way through the day today I started feeling nauseous and sweaty while I was driving. After not even 2 minutes of have these symptoms I vomited all over my car multiple times! I have been sweating with goosebumps and chills since my first dose. I will never take this medication again."

1 / 10
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  • MC3
  • Taken for less than 1 month
  • June 28, 2019

"I am taking a double dose of Bactrim (2 in the am and 2 in the pm) for a skin infection after a surgery. I have not experienced any of the flu-like side effects that have been mentioned below. I have a wound vac on, so it is hard to tell if the skin is healing."

7 / 10
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  • TJano
  • April 6, 2020

"It’s not a very fun game to play when you wonder if you’re coming down with the Rona. I have a moon looking infection on my nose. It was treated like shingles twice and it never went away so now I’m on Bactrim. the headache is severe I’ve never had anything like it in my life and I’m 52. I cannot quite explain-it’s like in the middle of my head behind my eyes but also when I turn my head hurts and can’t really move my head around. very severe. I took four ibuprofen then acetaminophen next and one Excedrin and it it’s not gone I haven’t slept a wink In two days. I’m exhausted and my heart rate was recorded as 100 when I did sleep."

1 / 10
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  • Scared...
  • Taken for less than 1 month
  • December 30, 2017

"I was prescribed Bactrim DS 800mg for 10 days after I had an infected abscess on my outer labia. I had incision/drainage and tested negative for herpes simplex, CT+NG DNA, MRSA, and staph. I went 8 days and noticed minor hand shakiness, a sunburn like itch/sting on my neck and collarbone and some right ab pain but didn’t think much of it. Day 9 happen and I wake up with a minor but expanding rash on my chest, neck, torso arms and legs. I went to ER and they said Bactrim allergic reaction, prescribed methylprenisolone steroid, and Hydroxyzine. 48 hrs since last dose of Bactrim lips are still dry, cracked and woke up with minor flat blood blister on inside of bottom lip. Is this still affecting me??"

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  • Cindy
  • Taken for less than 1 month
  • September 27, 2018

"I had a very widespread bacterial infection all over my legs and it spread to my arms thanks to a misdiagnosis at the first clinic I went to, but I was prescribed Bactrim from the second clinic. My rash has cleared up a lot and I've noticed a big change, but the debilitating nausea, cold sweats, and stomach aches are the worst. It will come and go in waves and it will wake me up in the middle of the night. I have eaten a lot when taking this and I drink a lot of water, but every time I take this I have to take an Advil because the stomach pain is just unbearable. Every time the painkiller wears off I feel like I'm dying. The result of the rash going away is worth it, but the pain and nausea is NOT."

3 / 10
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  • Kar
  • Taken for less than 1 month
  • November 3, 2021

"So I've had a small boil that turned into what I believe is a carbuncle because there were many heads/sore spots now about 5 or 6 all gathered around that 1 boil I noticed before it got bigger, its like they are all bunched up in a gumdrop/hill looking shape. The area would not drain on its own and the hill looking shape feels firm to the touch, I finally went to the doctor after not healing or draining on its own after 4 weeks. She told me to take this medication I took 1 pill at 7pm, around 7:40pm I felt my body feeling all kinds of sensations from head to toe. Around 10pm I noticed my hands were completely swollen!!! I got so scared, my right hand looked like a glove that got blown up, my left hand the veins were popping up so high and big, I called a 24/7 nurse line that comes with my insurance, she told me to keep my hand elevated and rest it and if it gets any worse to go to the ER. it took a day for my hand to go back to normal, I took no more doses, this is not for me"

1 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Bacterial Skin Infection

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Symptoms and treatments