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Sodium hyaluronate User Reviews & Ratings (Page 2)

Brand names: Durolane, Euflexxa, Supartz, Hyalgan, Gelsyn-3, Supartz FX

Sodium hyaluronate has an average rating of 5.3 out of 10 from a total of 629 reviews on Drugs.com. 45% of reviewers reported a positive experience, while 46% reported a negative experience.

Reviews for Sodium hyaluronate

  • Anonymous
  • Taken for less than 1 month
  • March 15, 2021

Durolane (sodium hyaluronate) for Osteoarthritis "Day three after my first Durolane shots in both knees. Right knee, no problem. Left knee, pain with some swelling for two days. Now feeling great! I am excited to see how the next few months go. Word of advice...ice, elevate and Aleve. Rest for 48 hours...it’s worth it! Good luck"

10 / 10
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60 Report
  • Dearie
  • Taken for 10 years or more
  • January 8, 2021

Euflexxa (sodium hyaluronate) for Osteoarthritis "Using euflexxa about 10 years and has extremely helped my my bone-on-bone pain. In the beginning it lasted up to 2 years w/o pain. I get them every 6 months now or longer if I have no pain. Better than steroids. Never had side affects"

10 / 10
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62 Report
  • Larry
  • Taken for 1 to 6 months
  • July 1, 2020

Durolane (sodium hyaluronate) for Osteoarthritis "I had both knees injected on Feb 7. I have had synvisc injections 3X's over the past 5 years. The doctor suggested durolane. She said, it would be one injection instead of 3 like the synvisc. The synvisc had worked great for me. Since she said it would work the same, I agreed to do it. The pain was unbearable!!!!!! When I left the office, I could barely walk. I had to keep my hand on the wall to maintain my balance. When I got home, it was very difficult to walk up and down the stairs. I can't believe they allow this injection to be used. It's been almost 5 months and I'm still having difficulty walking. I have a tingling feeling above the knee and in my foot. I'm sure there is going to be some lawsuits over durolane. This should never be used on anybody!!!!"

1 / 10
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68 Report
  • Jon
  • Taken for 1 to 6 months
  • January 31, 2024

Durolane (sodium hyaluronate) for Osteoarthritis "Durolane is AMAZING! I had my injection on Nov 1, 2023 and still have NO PAIN in my right knee. However, and I've noticed within this thread, the injection is BEST with ULTRASOUND GUIDANCE. If Durolane ends up outside the joint, pain is almost immediate. This is because of its high molecular weight. When you read this thread, guaranteed the bad reactions were because the injection was WITHOUT ultrasound and Durolane will take 6 months to break down - terribly painful. MAKE SURE YOUR DOCTOR USES ULTRASOUND AND CONFIRMS PLACEMENT!! I feel bad for people who've been getting injections without ultrasound."

10 / 10
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13 Report
  • johnm...
  • February 10, 2016

Euflexxa (sodium hyaluronate) for Osteoarthritis "I am a 36-year-old male police officer and avid outdoor enthusiast. I had my 2nd ACL surgery in 2012. I am very active, and having constant knee pain was not an option. My doctor decided to try Orthovisc injections to help with the arthritis. The Orthovisc worked great. Unfortunately, my insurance required my doctor to switch to Euflexxa. After my first injection, I was in incredible pain. The second shot, my knee swelled, and the pain was unbearable. The third shot was even worse. I ran a fever, had nausea, headaches; basic flu-like symptoms. I have read a lot of the reviews on this website. It seems like patients either have good results or results like mine. I want future patients to be aware of the potential risks."

1 / 10
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110 Report

Are you taking this medicine?

  • Al2020
  • Taken for 2 to 5 years
  • July 16, 2024

Durolane (sodium hyaluronate) for Osteoarthritis "I read these reviews 2 years ago after my physio recommended it over Ostenil. He then took it up with the Durolane rep, whose response was that the pain people get is when it is injected into tissue outside of the capsule. There shouldn't be any pain from the Durolane. So today, I had my 3rd lot of Durolane injections (both knees). Immediately no limp. They now offer lidocaine prior to the injection, with it being a gel. I recommend taking the lidocaine injection as Durolane on its own is uncomfortable due to its thickness going in. We've also recommended it to 3-4 other people who have all gone and had it. All are very happy. Both knees $900, worth every cent."

10 / 10
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1 Report
  • Anonymous
  • November 19, 2019

Gelsyn-3 (sodium hyaluronate) for Osteoarthritis "1st injection Nov 16th stopped my knee from popping and pain relieved. On my second injection 11/19/19 No pain with the injections. Make sure you get a doctor who has done a lot of these procedures and is good at it."

10 / 10
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69 Report
  • Godof...
  • Taken for less than 1 month
  • April 15, 2014

Euflexxa (sodium hyaluronate) for Osteoarthritis "I am a 62-year-old male who has played soccer up to the age of 44 when my knees stopped me. I have endured the pain from bone-to-bone osteoarthritis for over 16 years. The pain would be moderate sometimes and debilitating at other times. After my first shot of Euflexxa in both knees, 4 weeks ago, I was amazed at how pain-free I was walking around. I have just completed my 3rd shot and am still amazed. I am hoping to stave off TKR for as long as possible. Thanks to Euflexxa, this will be a reality."

10 / 10
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123 Report
  • Rocky
  • Taken for less than 1 month
  • February 21, 2020

Durolane (sodium hyaluronate) for Osteoarthritis "Upon reading all of the negative reviews, I chose not to have the injection. The following day I thought.... this is my only chance at having a better life! Well thank GOD I manned up!! I just had the shot a couple hours ago. The injection was OK 2/3 through but at the final 1/3 it did get a little uncomfortable but I knew things could only get better after this ! I say GO FOR IT! Better off giving it a shot Lol. Than to wonder if it would have...."

10 / 10
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65 Report
  • Rockc...
  • Taken for less than 1 month
  • June 5, 2023

Durolane (sodium hyaluronate) for Osteoarthritis "This stuff is awesome! The awful side effects that people have mentioned sound like what happened to me with a cortisone shot. It's NOT the injection or the medicine. Your doctor/PA/MA injected the needle into your nerve. I had the exact same thing happen to me. It took one month for the inflammation and pain to go away. The nerve pain was unbearable. I couldn't sleep, walk, sit, or stand up properly. Then, I went to a different PA who injected the Durolane above my knee, not into the nerves on the side. What a difference it made! It didn't hurt at all, not even the lidocaine. I experienced no side effects, just a little pain from the injection. But applying ice for 20 minutes on and 20 minutes off took care of that during the first 24 hours. I can't emphasize enough to most of you that Durolane is NOT the problem! You're suffering from intolerable nerve pain. This stuff really works and has made a huge difference in my quality of life!"

10 / 10
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23 Report
  • JanetDB
  • Taken for 1 to 6 months
  • February 26, 2013

Euflexxa (sodium hyaluronate) for Osteoarthritis "Have had knee pain for going on 10 years. Got to the point I couldn't take it anymore and went to an ortho doc. He said right knee total bone-on-bone osteoarthritis and left knee is following but not completely bone-on-bone yet. He suggested Euflexxa shots, saying the only other treatment would be a partial knee replacement. I figured it wouldn't hurt. I had the shots in December 2012. First shot, no difference. Second shot, seemed to feel better, 3rd shot no change. About a month after getting them, my knees still hurt. Figured it didn't work. But now two months later, I can actually go up and down stairs with minimal pain. I can go shopping and as long as it isn't an all-day affair, I do fine. Didn't take pain away completely, but it's better."

6 / 10
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130 Report
  • simpl...
  • Taken for less than 1 month
  • September 9, 2021

Euflexxa (sodium hyaluronate) for Osteoarthritis "I'd read several reviews about how bad the injection was, etc, and to be honest, they scared me to death. Today I just had my first injection. It was zero pain, and maybe it's in my head, but my knee already feels better. Typically on these sites you only hear from people who've had a bad experience. So far, for me - (fingers crossed) - it's been good."

10 / 10
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46 Report
  • Hurting
  • April 20, 2021

Gelsyn-3 (sodium hyaluronate) for Osteoarthritis "I received Gelsyn 3 injections in both knees, my doctor changed my medicine from Supartz to the Gelsyn 3 without consulting with me about the medicine change. I had extreme pain in both knees and dizziness upon leaving the doctor's office which only became worse along with injection site pain and excessive kneecap area swelling. Terrible bone and muscle pain all the way along my femur bones . Also hives around injection site. After each shot I had a terrible trouble walking and had to be on bed rest for 3 to 5 days after each injection. Rest assured I will never have these injections again, and as of today I still haven't had any relief and I'm still in pain everyday. The injections actually made my knees worse. I have problems from these injections and pain that I didn't even have prior to this terrible drug. I reportedly side effects to my doctor and the drug company but nobody seems concerned. I have never regretted anything more."

1 / 10
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49 Report
  • Sabrina
  • Taken for 1 to 6 months
  • November 26, 2019

Euflexxa (sodium hyaluronate) for Osteoarthritis "I am over a week out from my 3rd shot of Euflexxa in my knee. Pain in knee continues to worsen each day to the point that I can barely walk. I know this is not normal, but doctor won't listen to my complaints about this drug. Wish I never did the shots. P.S. My doctor recommended Monovisc, but my stupid insurance company would only approve Euflexxa. Not sure where to go from here...hope this disaster isn't permanent."

1 / 10
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60 Report
  • anony...
  • April 28, 2013

Euflexxa (sodium hyaluronate) for Osteoarthritis "I'm 61. Late last year, I began having very painful osteoarthritis in both knees. Dr. said I'm nowhere near bone on bone, but I could hardly move. I got cortisone shots which helped, but I still had pain and could hardly walk. I felt 100 years old. I just completed a series of Euflexxa and I am walking normally again! I have over 40 stairs in my house and I am so far back to normal! This has been a lifesaver. I thought I was permanently disabled but I'm walking with no pain."

10 / 10
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116 Report
  • Kneek...
  • Taken for less than 1 month
  • November 6, 2020

Durolane (sodium hyaluronate) for Osteoarthritis "I had one injection in each knee. The first 48 hrs I rested and limited movements. No pain nor swelling from injections. My left knee had been really painful 5-6months before treatment. Both knees are bone on bone. The pain from the stress on the left knee is subsiding daily now. I'm having to learn to walk normal again but I am so happy I had the injections. I will be having knee replacements sometime next year but this will give me time to loose weight and get my legs back in shape."

10 / 10
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48 Report
  • Masik
  • March 4, 2021

Euflexxa (sodium hyaluronate) for Osteoarthritis "After first injection it was very painful. Doctor told me I have to tell come to second injection. Now after third injection I can’t walk, terrible pain. What kind of experiment they did? What I have to do now?"

1 / 10
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44 Report
  • hunybun
  • July 31, 2013

Euflexxa (sodium hyaluronate) for Osteoarthritis "I just got mine today. I am 38 years old. I have some bone-on-bone. I found a great doctor. They marked my knees, sprayed something to numb it. BAM! NO PAIN, I FELT MORE PRESSURE THAN ANYTHING. Walking out, I felt AWESOME. NO CREAKING IN THE KNEES, AND I AM ONLY ON VISIT ONE. CAN'T WAIT."

9 / 10
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102 Report
  • sr335...
  • Taken for 1 to 6 months
  • August 2, 2021

Gelsyn-3 (sodium hyaluronate) for Osteoarthritis "I was seriously considering knee replacements, but at the age of 59, my doctor suggested getting these injections to get some more years out of my knees. I'm so happy I did it. I used to power-walk for 4 miles quite frequently, but with the arthritis I could just walk slowly for about a quarter mile. After the injections, I'm doing great and I'm back to power-walking. As of now, it has been two months since my injection."

10 / 10
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38 Report
  • ozano
  • Taken for less than 1 month
  • July 1, 2020

Durolane (sodium hyaluronate) for Osteoarthritis "Supposedly Durolane is artificial hyaluronic acid used for those of us who are allergic to eggs. Had a shot and could not walk our of the doctor's office. The pain was the worst I have ever had and I have severe OA in both knees, which in itself is a lot of unending pain. That knee now has a whole lot more excruciating pain. Can't recommend it because I think it harmed my condition."

1 / 10
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48 Report
  • Greg
  • Taken for 1 to 6 months
  • October 22, 2018

Gelsyn-3 (sodium hyaluronate) for Osteoarthritis "I had bad knees and had to hang on to the railing and felt a lot of pain going up the stairs. I had 3 injections of Gelsyn-3 around July of this year. I had wanted knee replacement but my doctor my doctor said that should be the last option. I had babied my knees because of the pain. Then the nurse told me that before I am given knee replacement they would like to see my knees get stronger. So I started exercising my knees which felt a little better after the injections. Now I can go up the stairs without pain and can sometimes try to scamper up the stairs. I will continue my exercises and after 6 months see if another round of shots is required."

9 / 10
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62 Report
  • Anonymous
  • December 3, 2009

Supartz (sodium hyaluronate) for Osteoarthritis "I was taking Vicodin during the day and Oxycodone to sleep at night because of the severe pain I was in with osteoarthritis. After a series of 5 shots in each knee, I have experienced complete relief for 2 years. Just recently I have started feeling the beginnings of some joint pain and am scheduled to begin the series of shots today. I'm hoping this round is as successful as the last."

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125 Report
  • Painful
  • October 23, 2019

Durolane (sodium hyaluronate) for Osteoarthritis "Yesterday I had the durolane injections done in both knees. I'm a 40 year structural ironworker and have severe arthritis in both knees. Cortisone shots in the past have not helped. After reading the reviews I had 2nd thoughts. I spoke to my general practitioner whom I trust and he recommended I get the shots. In the past I've had shots in the roof of my mouth, epidural injections in my back and I can say this was by far the worst pain I've ever experienced. I have an extremely high pain tolerance but have never experienced anything like this. My whole body clenched up and I had to breathe through it for 5 - 10 seconds. Then had to do it again on the other knee. I could barely walk after. Hobbled to my car more like. The pain subsided throughout the day a bit and I hoped to go to work the next day. Absolutely no way. I woke up at 4 a.m. in extreme pain and am now back to icing and heating my knees again and can barely walk. I WOULD NEVER WISH THE PAIN OF A DUROLANE INJECTION ON MY WORST ENEMY."

1 / 10
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53 Report
  • SC Girl
  • Taken for less than 1 month
  • February 11, 2020

Durolane (sodium hyaluronate) for Osteoarthritis "Today is Day 5 after my injection. I really regretted the decision on days 1-4. Yesterday was particularly bad with one of my knees buckling every few steps. Today I have no pain and I am greatly relieved. Apparently, the internal swelling caused the nerve pain. Swelling is gone and pain subsided. Yeah!!!"

10 / 10
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50 Report
  • AngieS
  • December 12, 2019

Durolane (sodium hyaluronate) for Osteoarthritis "I got a durolane injection on Tuesday. Just in left knee. So glad I decided against getting both knees done. First day was ok. I had some soreness but my pain continues to get worst each day. It is extremely difficult to get a good nights rest. I have difficulty walking. I was doing so much better prior to the injection. I did the one thing I tell everyone else. Don't put your faith in the doctor because they don't know everything. I so wished I had done my research then I would not be in this excruciating pain. No more of any kind injections for me. I can deal with my normal discomfort. But this pain is almost unbearable. Do your research!!"

1 / 10
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51 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.