Zoloft for Major Depressive Disorder User Reviews (Page 5)

• ros...
• Taken for 1 to 6 months
• September 10, 2018

"I've been suffering from depression and anxiety for as long as I can remember (I began having anxiety at age 5, panic attacks at 10, agoraphobia at 11, depression/panic at 12, and I still suffer from anxiety and depression to this day). Zoloft definitely helped at first, but I almost feel like my body is becoming tolerant to it. Is that possible? It also definitely kind of sucks the life out of you."

• Cro...
• Taken for 2 to 5 years
• June 1, 2021

"For me, this was the worst med ever. It made me suicidal, low mood, and low motivation. I do not tolerate SSRI or SNRI well. I feel doctors throw these at you without giving antipsychotics or benzodiazepines a fair chance. No 2 people react to meds the same, and for me, Zoloft was one of the worst meds."

• Dgi...
• Taken for 1 to 6 months
• September 29, 2018

"I took Zoloft for almost 3 months. Whether it worked or not didn't matter, as after I ate, within 10-30 minutes, I had diarrhea, flushing my meal right out of me. No nutrients equals no strength and weakness. Couldn't live like that, so weaned off of it."

• Jen...
• Taken for 1 to 6 months
• December 17, 2015

"Took Zoloft for major depression and anxiety. Started at 25 mg and went up to 75 mg over time. Didn't have any full-on panic attacks after starting the drug and noticed a lessening of my depression, however, I had awful insomnia even when taking it in the morning, and it didn't help my general/social anxiety as much as I hoped. The sleeplessness ended up making me more anxious overall and was not worth the benefits."

• jam...
• Taken for less than 1 month
• January 17, 2018

"Sertraline has done absolutely nothing to help my depression, it brought on anhedonia, which made me feel really down and just deeply sad. Waited 3 weeks and made me feel way worse. This is the 2nd SSRI I have used. I luckily respond very well to bupropion XL 300 mg, and it saved me from the complete hell I was in due to the SSRI. I don’t truly believe serotonin is the key to happiness, especially because I responded a hell of a lot better to Wellbutrin, which is a norepinephrine and dopamine reuptake inhibitor. All I can do is hope the new medication of ketamine nasal spray will do something good for most people who are suffering."

• sye...
• Taken for 1 to 2 years
• September 15, 2023

"I have been taking 200 mg of Zoloft for more than a year and am still ongoing. Even though I couldn’t retrieve the “old me” that I missed, I feel much better than I ever had for the last 3 years. With Zoloft, I am able to pass a day without crying, I am able to control my emotions better, and I have a decrease in suicidal thoughts (with other drugs, I couldn’t escape from the thoughts for every 1-2 days, but with Zoloft, it comes only when it’s triggered. The downside is my brain is ‘unscheduled-ly’ fogging, and I have a hard time especially during exams, but it’s much better than not taking it at all."

• The...
• Taken for less than 1 month
• February 28, 2017

"I took 75 mg for 3 weeks, and it didn't really move the needle for my depression. I thought around day 3 I felt a little better, but after that, it was pretty much back to being depressed as I had been before. I did feel like I was less easily angered by things, which was nice. It did not help my social anxiety very much or at all. Side effects were not too bad: a little drowsiness the first few days, some ringing in the ears, and decreased libido the first couple of weeks. The doctor has changed me over to Cymbalta, so we'll see if that works any better. I had high hopes for Zoloft, but I guess it just didn't work for me."

• Nic...
• April 9, 2019

"One day I felt good and the other very bad. I did not know what to think about this medication. I had good days and very bad days. After 3 months of taking it, I felt like it stopped working as well as it had before, so I stopped it and switched to another antidepressant. For the good days I had, I would rate this med 8/10, and for the bad days, 2/10. My bad days were more than my good days, it seems."

• Vyz...
• June 20, 2017

"It's hard to know if it's working. I feel down the majority of the time, and the only time I'm happy is when I'm ready for bed. I've been on Zoloft for 6 months now at 100 mg. I just want this to kick in already. Can I take anything else to help me?"

• Coc...
• Taken for 5 to 10 years
• April 12, 2023

"I had signs of depression and anxiety with school and home life from an early age, but I didn’t get diagnosed with major depressive disorder until I was 15 years old. My GP put me on Zoloft at 25 mg for one week, then put me on 50 mg. After a few years, she bumped me up to 100 mg and then lowered the dosage to 75 mg, which had me feeling way better. I saw my psychiatrist for the first time in 20 years, who recommended I go to the hospital to get off my Zoloft and put me on Pristiq. I was there for 6 weeks. I’m still currently on Pristiq 50 mg. Pristiq is working better for me than Zoloft."

• Dum...
• Taken for 1 to 6 months
• May 5, 2023

"Helped: impulse, need to cry, stress, happiness. Side effects: nausea, sweating, bad headaches/migraines, cold chills, loss of attention, pain, blurry vision. ⚠️NOTE⚠️ I took this from 11 to present, so it may not be the same for high schoolers or above or elementary students. Overall, it helped!"

• que...
• August 17, 2015

"Okay, I know these meds are supposed to help people, but I have been on a train to hell with these dang antidepressants! Zoloft.... ICK!!!! My God in heaven, I was sick for eight weeks on this stuff!! It never went away, in fact, the longer I was on it, the sicker I seemed to get. I lost five pounds, and just the sight or thought of food made me want to throw up! It made me feel even more depressed the whole time I was on it... I felt like a zombie, I was tired ALL of the time. Finally, I threw it away. My husband decided he wanted to give it a shot, so he went to the doctor to get a prescription for it. Eight weeks later, he was worse!"

• Ale...
• Taken for less than 1 month
• July 4, 2022

"I experienced very severe diarrhea with Zoloft, since the first day. It was so severe that I had to stay at home and have a toilet next to me. I stopped the medication after 2 days. I am non-tolerant to lactose, maybe that is the problem. I am sorry it did not work for me because they say it is the most efficient medication for general anxiety disorder and obsessive-compulsive disorder. I went back to paroxetine for the moment, which is good, but makes me too sleepy (12 to 15 hours of sleep a day)."

• Zol...
• Taken for 1 to 6 months
• April 15, 2021

"I predict this drug will be taken off the market. My neutral days are greatly reduced. I'm at 95%. My life is over. My whole life is trying to take care of myself. There is zero hope. I am full-blown anti-psychiatry now. I can't risk being badgered and rolled again by the 'profession' and made weaker."

• Juj...
• Taken for 1 to 6 months
• March 9, 2022

"First, I wanted to say that I was prescribed it for depression, anxiety, post-traumatic stress disorder, and social anxiety. I started it 4 months ago, and I’m currently on 125 mg but just recently changed it back to 100 mg. I realized that it was I felt happier and almost manic for the first month. The second month, I was on 50 mg, and it was okay, however, I will say that the negative side effects started at 100 mg. I have ZERO love for my boyfriend currently, and I feel like my libido has decreased. It’s really hard to climax even by myself. All my romantic feelings for my bf are basically gone. However, I am sexual still, as in my thoughts, I am still a sexual person, but I just don’t feel it when it’s actually happening if that makes sense. I know this because I have a huge crush on my bf’s brother, which is not good, but that means I’m still capable of feeling love and emotions, but they’re less intense for sure. Also, insomnia is pretty bad. It definitely works. Almost too well."

• Anonymous
• Taken for 2 to 5 years
• February 14, 2022

"I have been on psychiatric medication for nearly 4 years, my main medication is 300 mg of Wellbutrin XL, and it is great, but it does have a side effect of increased anxiety, something I already had. To counteract this, my doctor prescribed 25 mg of Zoloft, and that has done well up until a few weeks ago, and my dosage was doubled. It still works, but the sexual side effects are bad enough for me to consider stopping the med at all."

• Jus...
• Taken for 6 months to 1 year
• June 19, 2019

"No side effects or beneficial effects from taking this medicine. Felt severely depressed constantly. For me, I still think SSRIs are just a placebo effect, since when I first took it, I felt “good,” but then later realized how they work, hence knowing that it was just a placebo effect, from having such high expectations and not knowing anything about “antidepressants,” particularly the newer SSRIs..."

• Aly...
• February 9, 2017

"I've suffered from all four (panic, anxiety, depression, bad thoughts) for 7 years. I've never had panic attacks like I do now. I'm finding myself on the internet searching about panic/anxiety attacks. How are they caused? What causes them? Searching more into the answer I got, then searching more into that answer I got, and so on. It's to the point I'm scared to eat because I'm scared of having something to spike an attack. I try to avoid leaving my house, let alone the living room. My doctor gave me Zoloft 25 mg, and I'm so scared to take it. What if it makes me worse? What if it doesn't work? What if something happens while I have my kids alone? Can I overdose? Will I get addicted? I feel like I'm going crazy."

• Sil...
• Taken for 10 years or more
• April 26, 2014

"It keeps me from being suicidal. I have to have this. Great medicine."

• Mel...
• Taken for 10 years or more
• January 18, 2020

"Started at 50 mg Zoloft and now at a dose of 200 mg, a godsend to my life."

• cri...
• Taken for less than 1 month
• February 20, 2023

"I feel great. Best sleep I have had without any thoughts of the past."

• Ste...
• Taken for 2 to 5 years
• December 7, 2014

"I took Zoloft for a couple of years... It worked great for depression, but it absolutely killed my sex drive."

• Bet...
• April 26, 2016

"I've been on Zoloft for 4 years, and it's worked great for my depression. I take 50 mg per day."

• Coo...
• Taken for 1 to 6 months
• October 17, 2019

"Within the first month of taking Zoloft, my depression symptoms had decreased by about 70%. It helps with my mood, my sadness, and overall feeling of worthlessness. I would definitely recommend."

• KMa...
• Taken for 6 months to 1 year
• November 3, 2016

"It took me a while to reach an effective dose, but Zoloft was surprisingly effective. It does have a reputation of being a 'starter drug' and ineffective, but it has transformed my life."