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Zoloft for Depression User Reviews (Page 4)

Zoloft has an average rating of 6.8 out of 10 from a total of 585 reviews for the treatment of Depression. 57% of reviewers reported a positive experience, while 22% reported a negative experience.

Reviews for Zoloft

  • Chantel
  • August 13, 2009

"I started taking Zoloft about 3 1/2 weeks ago. The first week, I started to feel better. Though about 5 days in, I had a really bad hot flash where I had to lay on the floor for about 5 minutes, and then I felt like I was going to throw up. Haven't had that since. I do feel tired so I've started taking it at night. Also, I feel like I have restless leg syndrome. But other than those things, I am now able to focus, and my OCD seems to have calmed down a lot. I still get anxious, but it doesn't stick around as long, and I'm able to move on from it easier. I feel like I can live in the moment and not worry about my past or present or what issue I need to stop before it happens. I am able to focus better at work too. I think my husband likes me now."

8 / 10
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  • Kristy...
  • May 5, 2013

"My fiancé and I broke up, which made me depressed. Three weeks later, my mother passed away. I couldn't stop crying. A hospital was testing antidepressants on me. We decided that Zoloft worked best for me. It made it easier to cope, and I finally stopped crying. Eventually, I was able to get back to my normal life. I took it for about two months. If it makes you tired, take it before bed, which I did. I believe it saved my life."

10 / 10
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  • Sven
  • Taken for 1 to 6 months
  • July 13, 2021

"Works great for me! I started taking this after my son passed away from suicide. I am on a very low dose (6.25 mg). I had to go to a specialty pharmacy to get this dose. I am very sensitive to medicine. First week: Felt hopeful. Second week: Felt slightly more depressed. Third week: Back to normal. Fourth week: Slight improvement in mood. Fifth/sixth week: Much better. Side effects: None at all. Other coping mechanisms: Eating well, sleeping well, regular exercise, a therapist, a grief support group, a men's group, my dogs, talking about things with friends and family, staying open to my feelings. Overall: I am so happy I am taking this! My story shows that starting on a very low dose (which I don't see a need to increase now) can bring great improvements without any side effects. Hang in there! It does take time but it works great after about a month or so. And, work on your other coping mechanisms as well! Love to all of you!"

10 / 10
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69 Report

Frequently asked questions

  • I...
  • December 7, 2012

"I started using Zoloft on Wednesday the 5th of December 2012. Today's date is the 8th of December 2012. Four days, it has only taken four days for me to feel like a new person. I have been on it before, therefore I know what side effects to expect. Everybody is different, but I suffered from loss of appetite, headaches, nausea, feeling a bit dizzy, lower back pain, and trembling hands. This only lasts for a week or two. I used to cry for no reason (even at work), snap at my partner for stupid things, I was paranoid over everything, socially scared (I always wanted to stay home). I haven't cried since being on Zoloft, nor snapped at my partner. I am a new person now. I'm so happy and look forward to my new life. 100/100."

10 / 10
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189 Report
  • Slogg
  • March 17, 2014

"After a month of bouncing between morning and night dosing of 150mg pill, I settled on morning. It was making me super sleepy but that went away mostly. Didn't gain but maybe 5 lbs if that (I'm a gym rat somewhat). Felt really stoned the first week or so and sleeping was strange, maybe a little erectile dysfunction at first, but all of that went away too. A month in and the side effects are minimal. The panic is under control, but the depression is completely gone. THANKS A MILLION ZOLOFT."

9 / 10
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173 Report

Are you taking this medicine?

  • Erider
  • Taken for 1 to 6 months
  • August 20, 2012

"I have suffered from depression for a long time, but never believed it. I always said 'It's a rough patch, I'll come out of it soon.' Eight years on, I was down and out and suicidal. My doctor recommended Zoloft. I was skeptical and afraid of playing with my emotions. I thought being depressed was just 'me,' but I gave it a go. After 3.5 weeks, the most wonderful thing has happened. I feel normal. I can cope with my day, and I am hopeful about the future. There were side effects for the first week. I took my pill at night, which helped, and kept up the exercise; they passed. If I can give any advice, it's don't be afraid to take control of your body and don't feel guilty if you decide to try medicines. Listen to your doctor. You deserve to be happy."

10 / 10
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  • HardL...
  • Taken for 1 to 6 months
  • May 19, 2015

"This has been a life changer for me. I guess I never realized how depressed I actually was until I started on Zoloft. I'd been fighting it for years, forcing myself to get up and get by each day, but getting worse and worse (avoiding people, having problems talking, having horrible insomnia). Within a week of being on Zoloft I noticed a major difference. I actually feel optimistic about life for the first time in as long as I can remember. My relationships with my wife, family, friends, and coworkers have all improved dramatically. In short, I'm no longer depressed. I had some side effects over the first few days (restless legs, night sweats, a zonked out 'zombie' feeling) but they passed quickly."

10 / 10
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156 Report

More FAQ

  • Bloss...
  • March 8, 2013

"This medication has turned me around, and I had none of the side effects. I initially requested it from my doctor because, while I did not really have any problems, I had a negative outlook despite trying to be positive, and I was not enjoying 'life' at all. It has really helped with all this, and as an added bonus, I feel that I have more energy. I went back to my doctor and said 'We hit the nail on the head.' Previously, I was looking for the magic vitamin pill to help reduce my stress and increase my energy levels. I tried vitamin B, iron, and multivitamins to no avail. I no longer feel the need to take any vitamins at all. I'll continue to take this as needed and have no reservations about taking antidepressants."

10 / 10
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183 Report
  • Zatch
  • January 28, 2015

"Lately I've been having really bad panic attacks, migraines, night terrors/nightmares every night. For three weeks, I started Zoloft last night, and it already started working within a night. I'm more calm and feel like my old self already."

10 / 10
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159 Report
  • Louann
  • September 9, 2018

"Just take these reviews with a grain of salt. A lot of reviews after taking one day, couple weeks, etc. You need a full three months for maximum effectiveness. Not that it takes that long to start getting relief. Side effects are common while your body adjusts. Some of them will go away. I had no troublesome side effects with Zoloft. I always have to start out gradually. Maybe even more than they say because I’m sensitive to meds. I got big relief from depression. Panic attacks went away. OCD went away. The cons are it made me not very motivated, felt kind of numb to strong feelings. Not feeling urgency about my life. I wouldn’t take it again for years because it blocked my clear perspective. But it was great to get me stabilized. Things that really help but can’t completely replace anti-depression is fish oil, Vit D, exercise, sunlight, folate like spinach, lentils really good. Also, diet really helps. Get a book called the Good Mood Diet. Best wishes"

7 / 10
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110 Report
  • Joano
  • Taken for less than 1 month
  • August 27, 2019

"I just recently started taking Zoloft. I've been taking it for almost 3 weeks, so not a long time. But I've so far had a great experience with it! I have postpartum depression and anxiety. It was getting very hard for me to get up during the day with my kids and do stuff. I was tired all the time, no interest in anything or going out. Now, 3 weeks on Zoloft, I have started noticing I have fewer compulsive thoughts, I worry less, and I have been going to see my friends more. I still have to kind of force myself to get out and I still have my days, but it’s been working very well for me. I haven’t had any side effects, which is what I was worried about. I almost didn’t take it because I was so worried and fixated on the side effects. My sex drive hasn’t been affected, and I haven’t been nauseous or anything. I take it at night before bed, and it’s just been really great! I’ll update if any bad side effects happen, but so far it’s great!"

9 / 10
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95 Report
  • Lulu
  • Taken for less than 1 month
  • March 18, 2019

"Week three, I am feeling amazing and back to doing the things I enjoy. The first two weeks were horrible with nausea, fog, and anxiety. But I read on the link that you need to stick it out. So I did, and I’m glad. 50mg perfect dose. I no longer dwell on my situation, and I see all the positives. I noticed I find it very hard to cry. The dog across the road died, and it was heartbreaking, but I couldn’t cry. I can still think, feel, and be creative."

10 / 10
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100 Report
  • Lou
  • September 5, 2016

"I've been on the generic sertraline 50mg for about two weeks, and I feel so much better. I was very depressed, irritable, had insomnia, and felt like a total failure at life. I had a little diarrhea at first, but then I also have IBS so I wasn't surprised. After a few days, that stopped. I feel like my old self again, like a weight has been lifted from my shoulders. I'm even singing again, I haven't done that in about a year. I was in denial for a long time, I told myself I could handle the depression - I was wrong. This is the first antidepressant I've been on, and I am very pleased with how much it has helped me."

9 / 10
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132 Report
  • Trusso
  • July 18, 2015

"I was diagnosed with Generalized Anxiety Disorder, severe depression, and OCD when I was around 18 years old. I couldn't do anything and shut down. I went to a mental hospital to take classes on how to cope, and I began trying different types of SSRIs. I tried two others, and I felt horrible on them both. Then I tried Zoloft. My mom made me stick with it even though I was skeptical. I started with 25, 50, then to 75 mg. Nothing helped. As soon as I went up to 100 mg is when I felt my life coming back. I could feel emotions of happiness and felt like life finally had a meaning to it. I was able to be okay again and felt like this medicine saved my life. The thing that is hardest is all the people judging, saying 'you're on so many Meds'."

10 / 10
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145 Report
  • colle...
  • Taken for less than 1 month
  • February 2, 2016

"My depression began slowly at first, then all at once I couldn't bear myself anymore. I am a sophomore in college (female). In the evenings and going on into the night, my mood dropped so fast and I would get so sad over nothing. After talking to a counselor, and making the tough choice to medicate, she put me on a starting dose of 50 MG Zoloft. After taking the first pill, I was doing some research and had myself so freaked out that night that the side effects would be awful. I was so worried I would have to skip work or class. I have been on the medication a few weeks now and I had zero problems! I could not be more impressed. My moods are already stabilizing and I feel so much better already! Good luck to anyone starting!!"

8 / 10
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138 Report
  • Happy...
  • February 7, 2017

"It's so difficult looking at reviews because so many are negative. I have moderate depression and generalized anxiety disorder. I started taking antidepressants pretty young, maybe 6th or 7th grade. I took Lexapro, Prozac, and something else before I got on Zoloft. I just recently got off Zoloft to see how I'd do without it, and so far I've been okay. Anyways, Zoloft was practically a lifesaver for me. I'm not sure if I have experienced any of the side effects, but if I have, they obviously didn't make much of a difference. This review is here to say don't be scared to take Zoloft; it might be the perfect drug for you!"

10 / 10
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125 Report
  • Bucky...
  • Taken for 10 years or more
  • January 3, 2014

"I have to say that Zoloft saved my life. I have been on it for over 10 years, but about a year and a half ago, I switched to another pill just to try it. WHY I don't know, I should have never left Zoloft. I then started to take a muscle relaxer for a sore shoulder. BE VERY CAREFUL in taking other medications with any antidepressants. The dread, the worthlessness, the crying all came back. Back on Zoloft for about a week and I can function once again. THANK YOU ZOLOFT."

10 / 10
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162 Report
  • Santa...
  • Taken for 1 to 6 months
  • March 23, 2024

"Zoloft is a life saver! I recently left my ex-husband, and I was going through some weird, scary emotions. I would be very anxious at times. My psychiatrist put me on Zoloft, 25 mg, and it took the scary, anxious feeling away. I'm not that heartbroken anymore. The only side effect I'm having is bad heartburn. I'm on 50 mg now, and I feel great."

10 / 10
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12 Report
  • MayraP
  • December 30, 2016

"Long story short, I finally felt compelled to try antidepressants. I had experienced depression for a couple of years and had bouts of anxiety. The last straw was symptoms similar to bipolar disorder, like mania. I had been so reluctant to try meds, but man, I'm glad I did. I'm sad I didn't try them before. My life these couple years would have been so much better, less traumatic. I started 50 mg of sertraline in July. Right away, I noticed my mood improved. I used to be short-tempered, now I am more patient. I stopped crying every two days out of frustration due to my son's tantrums or misbehavior (challenging toddler) or from feeling overwhelmed with housework. Little by little, that fog of depression started to dissipate. I am happy now."

10 / 10
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121 Report
  • Ellie
  • Taken for 2 to 5 years
  • February 23, 2020

"I am glad to find a place that I can tell my story & maybe get some opinions. I started taking Zoloft when my husband of 53 years passed, that was 3 years ago. I had the doctor give me instructions on weaning from it in November. So now it has been 8 days off. I did not have any side effects until today. After I got home from church I just broke out in tears & I am not a crier. Is it normal to get this effect after 8 days off? I really would like to stay off the med. Thanks"

7 / 10
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80 Report
  • BAano
  • May 22, 2015

"Absolutely changed my life. I am a 20-year-old female who has struggled with depression and irritability since roughly 13. I tried meditation, I tried the 'power of positive thinking', I tried listening to podcasts, I tried counseling. Nothing helped me until Zoloft. I've been taking Zoloft for 5 weeks. I had minor side effects for the first couple of days (looser stool, headaches, stomach aches) but nothing I couldn't handle, and they went away after 2-3 days as I got used to the medication. I'm currently taking 50 mg and don't plan on increasing. I feel overall happier. I'm not as irritable, and things that I used to hate (going to work) are no longer even bad. I feel more myself, and like I'm not afraid to be outgoing. Highly recommended."

10 / 10
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136 Report
  • mickey
  • December 11, 2013

"Before I started taking Zoloft for depression and anxiety, I was also suffering from insomnia. I was taking Ambien and Valium to help, but the Ambien was not really helping my insomnia. Maybe I got 3 hours of sleep or 5 hours on a good night. I suffered from panic and anxiety attacks. I went to therapy, and after some time, the doctor recommended Zoloft. I was hesitant at first, but I could not live like this anymore, so I started taking it about a year ago. Zoloft is the best thing I could have done. The first week or two I had side effects, but soon after, the depression lifted and anxiety was gone. I sleep great now."

8 / 10
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150 Report
  • Perry...
  • July 15, 2009

"From the first week when I took this medicine, I can feel a slight change and haven't felt depression or anxiety. But as the weeks pass, I felt much better. I've got my life back, social skills, and feel like everyone else. This drug has really helped to bring my life back."

9 / 10
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193 Report
  • Seren...
  • Taken for 1 to 6 months
  • December 6, 2014

"I took Sertraline for Moderate Depression which it was exceptionally good at diminishing. I have been taking it for just under 6 weeks for moderate depression, social anxiety and generalized anxiety. It worked for depression the best, by far; however, not half as good for the anxiety, perhaps because it requires a higher dose and longer intake. Definitely consider Sertraline for depression, its side effects were minimal (if any because it was so unnoticeable)."

10 / 10
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134 Report
  • Lizbee
  • Taken for less than 1 month
  • March 5, 2016

"So far, this drug has saved my life. After experiencing a traumatic experience, I spiraled into a heavy depression coupled with anxiety. It's only been one week, and I'm no longer crying daily, and the hopeless feeling is subsiding. It's also helped stop the obsessive thoughts I've been having about the traumatic event."

9 / 10
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119 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.