Skip to main content

Rybelsus User Reviews & Ratings (Page 4)

Rybelsus has an average rating of 6.0 out of 10 from a total of 215 reviews on Drugs.com. 47% of reviewers reported a positive experience, while 28% reported a negative experience.

Reviews for Rybelsus

  • AJano
  • July 4, 2021

For Diabetes, Type 2 "I have been taking 3mg Rybelsus since June 4th. I am not experiencing nausea nor diarrhea, however I am experiencing constipation and lost of appetite. Since I have taking this medication I notice I get tired very quickly. Overall I notice that is has helped my diabetes tremendously and I have lost 8lbs with very little exercise. I also take metformin 750 ER. Before starting Rybelsus my A1C was 8.1, I do expect it to be much lower on my next visit in September."

10 / 10
Was this helpful?YesNo
20 Report
  • Mary...
  • Taken for 1 to 6 months
  • November 28, 2021

For Diabetes, Type 2 "I was on Metformin and had an A1c of 8. The dr told me to get off Metformin and gave me a sample of 3 mg Rybelsus, and prescribed the 7 mg dose after 1 month. My morning blood sugars with Metformin were 111 to 88. With Rybelsus my blood sugar in the morning has been 148 to 208.! I had diarrhea with the Metformin, but that went away with the Rybelsus, however my stomach has become bloated, lots of burping, slightly nauseous, no appetite, a tightness of my chest and now that I am using the 7 mg dose, I have become exceedingly tired with zero appetite. Today my blood sugar was 177. This is unacceptable. It was way lower with the Metformin. I am quitting this. I can't be this tired and feeling so ill. I used to have energy with the Metformin, but Rybelsus has completely drained it. I feel the dr had just been visited by the Big Pharma Salesman and gave her the sales pitch and she started prescribing it. Is she getting a kickback?This Rybelsus is not good, and causes cancer."

1 / 10
Was this helpful?YesNo
18 Report
  • Jackra
  • Taken for less than 1 month
  • December 24, 2020

For Diabetes, Type 2 "I am 70 and was diagnosed with type II Diabetes about 7 years ago. I have always been on Metformin and have tried medications like Farxiga and Janumet both of which give me bad leg pains after a while. I started Rybelsus, 3 mg, about 6 weeks ago and after 3 weeks felt so bad I stopped taking it. The worst feeling was quite bad lower back pain and a sort of fatigue. It was a generally weird feeling of malaise not just fatigue. So if an introductory dose of just 3mg is any indication a stronger dose would be terrible for me. So now I am on the max doseage of Metformin and my last A1c was 7.6. 7 years ago it was 6.5. I would add that at most I have been about 15lbs overweight and there has never been any incidence of Diabetes in my family."

1 / 10
Was this helpful?YesNo
22 Report

Frequently asked questions

  • tuf2b...
  • Taken for 1 to 6 months
  • August 6, 2021

For Diabetes, Type 2 "I love my Rybelsus. My numbers are so much better. I can stay in my target zone for the 1st time in years. I'm excited for my next A1C instead of dreading it. No side effects at all except pure joy. 24 year type 2. Metformin and Glimpride. I was in the high 2 to 3 hundreds. Not anymore."

10 / 10
Was this helpful?YesNo
19 Report
  • rickle
  • Taken for 1 to 6 months
  • December 28, 2021

For Diabetes, Type 2 "I've been on Rybelsus for a little over a month for PCOS and have had an overall positive experience - just started the 7mg dose. My doctor recommended it since I am at risk for type 2 diabetes (>30 BMI, borderline high fasting glucose with a normal A1C, and signs of insulin resistance from PCOS). I get some pretty extreme nausea whenever I eat junk food (fatty and/or sugary), but otherwise feel good. I'm hoping that the nausea I do get helps instil better long-term eating habits. I've also experienced appetite suppression, which has helped me prioritize proteins and vegetables. I did get alternating bouts of constipation and diarrhea when starting this medicine, and am expecting that I'll experience the same with the dose increase. I have felt far more energy and my cravings for junk food have drastically reduced. So far, I've lost slightly more than 10lbs and am shooting for another 50 to help get my PCOS under control."

10 / 10
Was this helpful?YesNo
17 Report

Are you taking this medicine?

  • Lynn
  • Taken for 1 to 6 months
  • December 18, 2021

For Diabetes, Type 2 "I took 3mg for 2 months and then started the 7mg. The 3mg I had heartburn, nausea, some diarrhea. Was uncomfortable but doable. But once on 7mg. I had the same symptoms plus vomiting, constipation to the point of hemorrhoids and severe heartburn to point I almost went to ER. I got out the label on this medicine Rybelsus and relooked up side effects symptoms on computer. I immediately stopped on my own, messaging my doctor. Within 2 days felt so much better. This medicine is costly too, luckily I had insurance because I will not use this and it had to be disposed of. $ wasted."

1 / 10
Was this helpful?YesNo
17 Report
  • CRK
  • Taken for less than 1 month
  • July 16, 2021

For Diabetes, Type 2 "My doctor gave me a sample box of 3mg Rybelsus for T2D. I could only tolerate it for 10 days. The first thing I noticed was my appetite was gone. As days went on, I felt like I was in my first trimester of pregnancy, although I didn’t ever feel like vomiting. Continuous nausea, lack of appetite, lethargy and horrible constipation were my friends during the time I took the drug and for about a week afterwards. I ended up in ER with terrible IBS with very painful cramps. I thought I had a blockage from no BMs for 12 days. After being off the drug for about a week, one day I woke up and the symptoms were gone (about a week after I stopped taking it). I felt like myself again. During that short time period, the pounds just started melting off me, and I only weighed 138 going into this. I dropped down to 130. I really wanted this drug to work for me. My doctor tried to prescribe Trulicity after this. No way. It’s too similar. My A1C is 8. Not sure where to go from here."

4 / 10
Was this helpful?YesNo
19 Report

More FAQ

  • Herb
  • Taken for 1 to 6 months
  • January 30, 2021

For Diabetes, Type 2 "Was on 3mg Rybelsus for a month. Nauseous all the time. After a month went onto 7mg for a month. Nauseous all the time. After a month moved onto 14mg. Nauseous all the time.... This drug is awful"

3 / 10
Was this helpful?YesNo
21 Report
  • Anonymous
  • March 26, 2022

For Diabetes, Type 2 "Beware. My doctor had me transition to 7mg after only being on the 3mg for two weeks. I could not stop vomiting after taking the pills for 5 days. I lost a ton of weight but ended up in the hospital getting my gall bladder removed and not eating for two weeks."

1 / 10
Was this helpful?YesNo
15 Report
  • NP2021
  • Taken for less than 1 month
  • July 24, 2021

For Diabetes, Type 2 "28 days in! Started on 7mg and will continue with 7mg. I am also on Metformin 500mg daily and have been for years. To be fair, my A1c was never above 6.3 and my weight was 179 lbs and height is 5-6. I have a strong family history of insulin-dependent diabetics and I don’t want to go there! I’ve been losing weight like crazy with no exercise which is why I came to read some of these reviews to see if this is common. Current weight is 164. Lost 15 lbs in 28 days! Mild nausea and dry mouth after taking med in the morning. Pill is also bitter and not overly large, but a little hard to swallow. Nausea disappears with ginger ale or fruit. Appetite is gone! I have to force myself to eat at times. I suggest a vitamin supplement. Mild stomach ache and loose stool later in day but have solid soft stool in the morning. Want to continue to reach weight goal of 155lb and A1c below 5.8. Then maybe go to a reduced dose if necessary. I definitely recommend this drug."

10 / 10
Was this helpful?YesNo
18 Report
  • Jess
  • January 28, 2021

For Diabetes, Type 2 "I am a 38 yr old women with lupus and fibromyalgia. I was on farxiga 5 mg twice daily and my sugars were crazy my a1c stayed at a 7.4 and I was always hungry. My doctor put me on Rybelsus 3 mg I’m on day 12 and I had the nausea and bloating if I ate my normal way if I ate in moderation I was good. Haven’t seen weight loss yet but I like how I’m not starving all the time and glad to see the bloating stops and nausea also . Great drug .exciting see the results . Oh and in November I was a a1c of 7.4 and now it’s a 6.4"

10 / 10
Was this helpful?YesNo
20 Report
  • Hastica
  • Taken for 6 months to 1 year
  • December 7, 2022

For Diabetes, Type 2 "I have been on Rybelsus for almost 7 months, the first 3 months I was on 3mg, Then increased to 7mg three months ago... I was previously on glimepiride and metformin for blood sugar control, but I was having multiple LOWS. My Dr replaced the glimepiride with Rybelsus. So far, I have lost 44lbs and my A1C went from 7.3 to 6.6 after only 3 months. The only side effect I have is decreased appetite, which has helped immensely with the weight loss. I think this is a weight loss drug. With the weight loss and decreased appetite, obviously, your A1C levels are going to be lower. I am happy with the weight loss, I am just concerned as to when it will finally plateau and even out and if my appetite will return at some point. I have also been suffering from some insomnia, but suffered from that periodically prior to the change of medication. I wish my insurance would cover it at the Copay of 10.00 instead of it being on the list of higher-cost medications."

8 / 10
Was this helpful?YesNo
11 Report
  • Michele
  • Taken for 1 to 6 months
  • July 5, 2022

For Diabetes, Type 2 "My first 30 days at 3 mg weren't bad. I enjoyed not feeling hungry and only experienced mild diarrhea after eating occasionally, though it wasn't triggered by specific foods, so I always needed a bathroom plan. In my last week of Month 1 on the 7mg I had watery diarrhea with nausea for 24 hour periods, 3 times in 10 days. I vomited one of those days. I haven't had my bloodwork checked and I know I lost weight, but I also lost more than 3 days of my life sitting on a toilet. I ate nothing that would have triggered these episodes. Rybelsis has done one good thing - inspired my butt to get serious about my health without drugs."

5 / 10
Was this helpful?YesNo
13 Report
  • jeanj...
  • Taken for 1 to 6 months
  • April 7, 2024

For Diabetes, Type 2 "I'm disappointed with the lack of weight loss, however, my blood sugar is constantly lower as I'm type 2 diabetic. I need to lose around 6 stone and was hoping this would help. I'm a month into taking it and no weight loss. I was on liraglutide for 5 years, and that didn't affect my weight either. So disappointed. I hope I start to see some loss over the weeks."

5 / 10
Was this helpful?YesNo
3 Report
  • Ramin
  • Taken for 6 months to 1 year
  • October 26, 2021

For Diabetes, Type 2 "I used for an almost a year, will never go for it again, It slows down stomach emptying and later the whole GI, slows down almost every organ. Takes longer to show its effect and Hgb A1c stays higher for most of the people unless you starve your self. You retain fluids also."

1 / 10
Was this helpful?YesNo
16 Report
  • Amreeta
  • Taken for less than 1 month
  • December 20, 2023

"I am hypothyroid and have difficulty losing weight. I was overweight as well. I was prescribed Rybelsus by my doctor. From the first 3 mg onwards, it was extremely effective. I felt an immediate lowering of appetite. I felt very sleepy the first three weeks of the 3 mg dose, but then that quickly settled. My energy levels are now stable. I work out every day, a combination of cardio and weights. I have lost 7 pounds in 25 days. I am still on the 3 mg dose. My appetite is extremely suppressed, and I can go long periods without food. I have no dizziness or anxiety. I will stay on this since I have another 8 pounds to lose. This low dose worked very well for me."

10 / 10
Was this helpful?YesNo
5 Report
  • Quin
  • Taken for less than 1 month
  • January 30, 2021

For Diabetes, Type 2 "I have been taking 3 mg for almost a month now and not really any symptoms. I think I got nauseous one time and that was it. I also take a vitamin D twice a week with it and have been fine. I was given the medication due to having high insulin and weight loss and will start 7mg next week. Can’t wait to see how that goes."

10 / 10
Was this helpful?YesNo
19 Report
  • kitten
  • Taken for less than 1 month
  • August 2, 2021

For Diabetes, Type 2 "Rybelsus made me really sick. I didn't realize it until a couple of days ago. I thought I had a virus. I was practically leaning on the wall every day trying to pull myself out of work to the car. Last week I spent a lunch time laying on my office floor and then just left early. It is more than the nausea, it was fatigue, significant dehydration, confusion, dizziness, headaches... I'm still feeling sick after 2 days not taking it. I just read that it can take a couple of weeks to get out of your system."

4 / 10
Was this helpful?YesNo
17 Report
  • Kandace
  • Taken for less than 1 month
  • October 3, 2021

For Diabetes, Type 2 "My blood sugar was always in the 200-300s. Now it’s been at 130. Very good. I don’t eat as much anymore. Don’t crave any junk food like I use to before. I am losing weight. I’m shocked first thing that has ever helped me. The downfall for me is I can’t use the restroom. I already have issues with that, & it’s gotten way worse. Also I wanted to know has it made anyone else sex drive go down hill? I use to be all into it, & now I’m like ehh. It’s pretty sad."

7 / 10
Was this helpful?YesNo
16 Report
  • Daisy
  • Taken for 6 months to 1 year
  • February 5, 2024

"Hi, I've now been on this medication for 1 year. (Please see my previous review, the top-rated one.) I have lost 56 lbs. I currently take 14 mg. 3 mg per week. In week 3, I felt a bit headache and sick, so sometimes I missed a day. That really helped. After about 4 months, I went up to 7 mg. I had similar side effects in week 3 with this mg, so I would just miss a pill if I felt dodgy. Don't be so fast to jump up the ranks for weight loss. You want to maximize each mg as once you get to 14 mg and it stops working, there's no higher dose and it's the end of the road. For me, it's been an amazing pill. I used to binge drink once or twice a week. This pill has put me off alcohol. I hardly drink now. Bonus!"

9 / 10
Was this helpful?YesNo
4 Report
  • John...
  • Taken for 1 to 6 months
  • March 7, 2023

For Diabetes, Type 2 "I started with the 3mg. Within a week my bowel movements became loose. Other than that it was fine. Started the 7mg after a month. Within a week I was nauseated constantly, along with diarrhea. The nausea got worse and diarrhea continued. At three weeks I had to stop taking it. The very next day nausea stopped and I have normal bowel movements again. I do not recommend this medication. Also, vomiting was a relief a few times."

1 / 10
Was this helpful?YesNo
9 Report
  • britt
  • Taken for less than 1 month
  • June 30, 2021

For Diabetes, Type 2 "Stay away!!! I’ve been taking Rybelsus for 1 week and in that week I’ve stayed extremely hungry, gained 4 pounds, increased agitation, numbness in feet, muscle pain and cramping. I contacted my doctor and she said to discontinue use of this medication and to start back on my metformin."

1 / 10
Was this helpful?YesNo
16 Report
  • AnnieA
  • Taken for 1 to 6 months
  • April 7, 2023

"I started this medication on Dec 20th, 2022 3mg when my doctor told me I was diabetic. I weighed 206 lbs. A1C 6.5 the first month on this I was nauseous and felt sick. At 30 days I told him what I felt. He said I am putting you on 7mg now. Your body will get used to it. Here I am now 3 months later & I am so sick. I get nauseous still, have constipation, diarrhea, and loss of appetite, and the smell of food at times is so nasty. I am constantly feeling sick, dizziness and I feel lightheaded, always exhausted, no energy. Which scares me. My A1C is lower now 6.1 I have pretty much stopped having sweets, carbs, or anything bad. Weight loss is out of control. My current weight is 157 lbs today when I went to the doctor. I have lost 49 lbs in 4 months. I told him I can’t take this anymore. He changed me to metformin 500mg let’s see how this one works. This medication hurt me more than it helped me."

1 / 10
Was this helpful?YesNo
8 Report
  • catch...
  • Taken for 1 to 6 months
  • June 23, 2023

For Diabetes, Type 2 "I have been taking Rybelsus for about 3 months. I have had nausea and weight loss. My blood glucose level is much better. It's even sometimes low. I now wear a continuous glucose monitor. I have random nausea after taking the medication in the mornings and can experience nausea during the day if I eat too much or greasy food. I think this is what causes some of the weight loss. You just don't want to eat if you have nausea. I do occasionally get a headache and constipation if I don't drink lots of water. The drug makes me not want to eat, but it also makes me not want to drink, so I have to force myself to drink water, or I get dehydrated and constipated. This drug makes me forget to eat or drink. It's strange. The good side effect is weight loss. Bad is nausea. My insurance does cover it."

7 / 10
Was this helpful?YesNo
7 Report
  • Susie
  • Taken for less than 1 month
  • December 29, 2020

For Diabetes, Type 2 "I have only been on Rybelsus 3mg for two weeks and I haven't had any nausea at all, the only side effect I have been experiencing is an increased appetite. I can't get enough to eat. I also take Metformin and Glipizide and have never had this type of reaction. Once I finish the 3mg, I am going to ask my Doctor to increase this medicine to 7mg and I hope this will eliminate the constant cravings. I really want this medication to work and get my A1C under 7."

5 / 10
Was this helpful?YesNo
17 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.