Rybelsus for Diabetes, Type 2 User Reviews
Rybelsus has an average rating of 6.2 out of 10 from a total of 227 reviews for the treatment of Diabetes, Type 2. 45% of reviewers reported a positive experience, while 27% reported a negative experience.
Reviews for Rybelsus
- Ann...
- December 28, 2020
"I started taking Rybelsus at the beginning of August for weight loss. The biggest con for me is that it causes constipation and then usually diarrhea when I finally do go to the restroom. I have only had issues with nausea when I try to eat past the point of being comfortable. It is also important to try to eat something within an hour of taking the medication. When I first started on the medicine, I could only eat a few bites of food and then would feel extremely full and bloated and would have to stop. Now, it is 4 full months later, and I am on the 14mg, and I can continue to eat beyond a few bites without feeling miserable, but I try to stop as soon as I am full. I have, so far, lost 30 lbs with no exercise and have gone from a size 12/14 to a size 6/8. Diabetes does run in my family, so I am hoping continued use of this drug may help prevent the development of diabetes in the future."
- The...
- Taken for less than 1 month
- April 6, 2021
"It’s been a week on Rybelsus 3mg. I feel pretty good (except for seasonal allergies). No nausea, no vomiting, no diarrhea, smaller appetite. I am prediabetic with BMI >30. I would like to lose 30 to 40 pounds. I think Rybelsus will help me. (Prior to taking Rybelsus, I was fasting (16-hour/8-hour) and exercising EVERY day and STILL gaining weight.) I think Rybelsus will help. I weigh daily, and I am beginning to see the numbers ever so slightly trend down. I am optimistic. I will start 7mg after 30 days. I hope to come back here and share my journey with you."
Frequently asked questions
- How much does semaglutide cost?
- What foods should I eat or avoid when taking Rybelsus?
- Rybelsus vs Ozempic for weight loss: Which to choose?
- Can you just stop taking Rybelsus?
- 2Ti...
- Taken for 1 to 6 months
- January 18, 2021
"For 2 years, my diabetes went out of control to the point that I started having some mental issues like brain fog. My doctor put me on 3mg Rybelsus. The first two weeks were a bit of a struggle, nothing I couldn't handle, just nausea and no desire to eat. A month in, my doctor took me up to 7mg. The first week at 7mg was the same, nausea, but after the week ended, it was gone. I still don't have a major appetite, which is excellent. My blood sugar is 104 at this moment. I've lost 24 pounds so far in 6 weeks. I love this stuff. I also feel much better, and I can actually think without the fog. I recommend it."
- Gum...
- Taken for 1 to 6 months
- February 28, 2020
"I’ve been on Rybelsus since 1 December at a dose of 3 mg. January 1, I started 7mg. I don’t like taking medication and was scared of this medication due to other reviews I have read. I am very pleased with the outcome. I lost 5 lbs with very little exercise. My side effects were nausea and loss of appetite. Nausea only occurred when I ate junk food and sweets. A1c down from 7 to 6.2. Plus, I do not take any other meds for diabetes. Hope my review will help others. February 28."
Are you taking this medicine?
Your review helps others make informed decisions.- Koo...
- May 1, 2021
"I have been taking Rybelsus for 6 months. At first, I was nauseous and had bad sulfur burps, but it went away. My A1C is the best it's been in 9 years. I have had a hard time treating my diabetes, as most other oral medications and daily injections just made life harder. Now, my numbers are 6.7, and I have lost a significant amount of weight, 335 lb to 285 lb, with minimal effort. It definitely suppresses my appetite. I've read you can only lose a few pounds, but I feel like a lucky one."
- Con...
- Taken for less than 1 month
- March 26, 2023
"I took 3 mg of Rybelsus for about two weeks. I noticed right away that I was not able to poop normally. I thought constipation would resolve naturally since I don’t have issues with it normally. Now, I’ve been off of it for a week and I’ve had two ER visits because I can’t poop. I also struggle to pee because the thought is the backed-up poop is pressing on things it shouldn’t. Had to have a catheter drain me out. I did a week of Miralax, two days of Dulcolax, one ER cocktail, and an enema, and none of it has helped. At this point, I’m scared it will take surgery to remove the poop. If you’re taking this medicine please stay in tune with your body and mitigate early if you’re starting to experience any constipation."
More FAQ
- Rybelsus Copay Card: Do I qualify? Savings explained
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- joe...
- November 20, 2020
"I first took the 3mg dose for 30 days. I had no side effects, and it is really controlling my appetite. Now I am on 7mg. So far, my weight was 242. I have been on Rybelsus for about 4 months, and my weight now is 215. I'm hoping to lose more. No side effects, feel better, light food craving. I hope to stay on this for 4 more months. Thanks Rybelsus. Joe C."
- Jen...
- November 29, 2020
"My doctor put me on Rybelsus in March/April 2020. I will admit the nausea was pretty bad for about the first month, but I stuck to it because it was really working well on my blood sugar. Since I started, I have lost 42 lbs! I have not been dieting, but I do have some outdoor projects that required physical labor, like shoveling dirt, clearing brush, moving stones, etc. The nausea only comes back when my sugar is low and I really need to eat. I don’t even get a growling stomach anymore. I would recommend Rybelsus to anyone looking to manage their blood sugar and lose some weight."
- Ami...
- Taken for less than 1 month
- February 13, 2022
"I was very frightened after reading the reviews. I am 52 and had gained from 130 pounds to 158, the most I have ever weighed in my life. Started the 3mg 3 weeks ago and have lost 10 pounds with no side effects other than occasional slight nausea. My appetite has decreased but for the better. I am walking 3 miles a day and eating very healthy. Stopped drinking soda, now only flavored water. I consider this a miracle. Never lost weight this quickly. Happy as heck. Will continue the 3 mg and recheck A1C. So far this rocks. If it enables me to get in control of my eating and lose to a healthy weight to better my overall health, then I call it a huge success. Love, love, love it!"
- Can...
- Taken for 1 to 6 months
- November 29, 2020
"When I first started the 3mg of Rybelsus, the nausea for the first 3 weeks was nearly unbearable. However, like magic, around day 21, it stopped. I don’t feel as full as I did at the beginning now that I’m starting my second month of 7mg. However, I continue to lose weight with diet and exercise. If you’re struggling at the beginning - hold on for 30 days - it might pass like it did for me!"
- Dor...
- Taken for 1 to 6 months
- December 21, 2020
"I started taking Rybelsus 3mg. I was nauseous at first and constipated. I was also belching a lot. After 2 weeks, that seemed to stop. I've been on the 7mg for 17 days and the nausea, indigestion, stomach pain, and now diarrhea have been almost unbearable and are getting worse. I've also started feeling panicky and anxious in the middle of the night with rapid heartbeat. I'm stopping the 7mg tomorrow and calling my doctor. I can't feel like this at Christmas. Going to see if she will put me back on 3mg. My A1C was 9.0. I have no idea what it is now. I've also lost 18 lbs because I can barely eat anything. This isn't worth it."
- Sai...
- October 17, 2020
"Dr. ordered 3mg 30 days ago to be added to Metformin 2000mg. Blood sugars have decreased from a range of 200-350 to 120-150. Weight reduced by 14 pounds. I experienced nausea and fullness for the first two weeks. That has tapered off but appetite suppression has continued. After a month, the doctor is pleased with the results, as am I. He has ordered me to continue on the 3mg and my insurance has agreed to cover it with a copay I can afford. I am so grateful for this new med!"
- joa...
- Taken for 1 to 6 months
- August 15, 2020
"Dr put me on Rybelsus since I had bad luck with Trulicity and feeling sick every time I took the shot. The first month of the dose 3mg, I noticed I never ate. I had a complete lack of appetite. I was exhausted, had weird dreams, and a constant feeling of anxiety, and sometimes insomnia. I put up with it. The second round with the 7 mg, the first day I was sicker than heck. I felt like I was on a cliff dangling, my anxiety turned into panic, rapid heartbeat, and I was unable to sleep. I stopped after day 4. I called the doctor but she never got back to me. I am debating trying to take 7mg every other day or go back to the 3mg and see if there is a difference now that it is almost out of my system. It is brutal to the body. The warnings say nothing about the feelings of anxiety or the insomnia."
- CAD...
- Taken for 1 to 6 months
- December 13, 2020
"I’m prediabetic, HbA1c 5.7. And I’ve been struggling to lose weight for 20 years. I have an excellent diet, but I eat too much. I’m hungry all the time. I started Rybelsus (paying out of pocket - Ouch) to see if it’s worth hassling my insurance company. On 3 mg, I felt nothing - no nausea, but experienced loose stools. When I went to 7 mg, I felt nausea for 1 hour after taking the pill and decreased appetite the rest of the day. I am easily staying on my 1400-1500 calorie diet, which has never been easy for me in the past. At 1 month of 7 mg, I’ve lost 8 pounds (255 to 247) and feel very encouraged. The science behind this medicine is inspiring."
- siv...
- Taken for 1 to 6 months
- December 10, 2020
"My doctor put me on Rybelsus as I had high blood sugar. I had too much difficulty taking the 3 mg with nausea, diarrhea, and headache. I planned to quit, but I read the reviews here. I somehow managed my symptoms and tried harder. My doctor then increased the dosage to 7 mg. Rybelsus was able to bring my blood sugar levels from 10.6 to 5.6, almost normal levels in a period of 3 months. If anyone is planning to quit, please persevere, and the results are amazing. It practically stops your cravings for food and helps you stabilize. Another miracle was that I was finally able to quit coffee in the morning as I get migraines without it. Compared to the nausea, diarrhea, and the churning of the stomach, migraine wasn't a big deal, and I finally went without taking coffee. This is really a miracle drug for diabetes. Thank you."
- Typ...
- Taken for less than 1 month
- April 26, 2023
"I have been taking 3 mg Rybelsus for 14 days for type 2 diabetes alongside Metformin. I have had no negative side effects from this medication other than a low blood sugar reading most days. I take it around 6 am with a small amount of water as directed and then breakfast around an hour later. I have lost 14 lb in weight, but I have started eating very healthily with a low carb intake. My appetite has reduced and my portion sizes have reduced as I do feel much fuller for longer. So far, so good."
- Fat...
- Taken for 1 to 6 months
- March 27, 2021
"My A1c has been hovering around 7, and my weight was creeping up, so my doc suggested this. I started on the 3, and the nausea and projectile vomiting were rough... indeed, I didn’t think I could handle it. Then I discovered if I take it when I wake in the small hours to pee, if I took it then, I had almost no problems. I’m now up to the 15mg dose, and so far I’ve gone from around 255lb to about 220lb and falling. Two whole jean sizes... haven’t done new labs yet... but the weight loss is remarkable... it’s also quite weird to essentially almost never feel hungry anymore."
- sta...
- March 13, 2023
"Started the 3 mg for one month and lost 7 lbs. I read the reviews about the side effects and saw most have little side effects if taken early, so I take it around 5/6 AM with little water. By the time I'm ready to get going for the day, I can have a cup of tea, as it says not to drink within the hour of taking it. My appetite has decreased, I don't pick/snack, and my portion size has decreased. I only ever feel nauseous if I eat too much, but I've got to grips with how much I can eat, and to be honest, I don't really feel hungry. I was eating because I felt I should. No other side effects. On my second month, so will see how it goes."
- Jan...
- March 26, 2021
"I started on Rybelsus and only took 4 doses. I didn’t get terrible stomach upset, but my abdomen went completely numb. I’ve been off the medication for 4 days and am still completely numb. I went to the ER, and they ran blood work and a CAT scan, all was normal. I went to a chiropractor, and again, all was normal. Numbness is listed as a rare side effect on drugs.com website, which my chiropractor looked up. My endocrinologist isn’t helpful, and I called Rybelsus, and they were less than helpful. I’ve now spent hundreds of dollars. I’m very concerned and praying this goes away. I am so numb it hurts to touch my skin. Beware of this medication!"
- Won...
- Taken for 6 months to 1 year
- September 9, 2022
"Was placed on this medication to help with PCOS-caused insulin resistance and obesity. The first two months were a bit uncomfortable - I was nauseated a lot and had bouts of constipation and diarrhea. Fortunately, immediately starting it, my sugar cravings disappeared. I think I had a rough couple of months because of my old eating habits since this medicine slows how fast your stomach empties. As I developed better eating habits, this has gone away completely. I’ve been on this for almost a year now and have lost almost 60 lbs. I’m about 5 lbs away from being a normal weight and I’m barely making any effort at this point; the weight is just coming off. I feel the healthiest I’ve felt in over a decade and have been seeing my PCOS symptoms reduce as the weight comes off. This medicine was a miracle for me. I’ve struggled for a decade trying to get my weight under control. Once the insulin resistance was resolved, it literally fell off."
- Bun...
- Taken for 1 to 6 months
- October 11, 2020
"I have read a lot of the comments. This medication has helped lower my A1C. I am down from an 8.1 to a 6.5. When I started it, I was weighing 238 pounds, now I weigh 217. I was wearing a size 18W/20W, now I am at size 16W. I don't want to get too small. I like the way my clothes fit on me. The only thing that I have read about taking this medicine is that it can cause Thyroid cancer. So I may stop taking it."
- Sue...
- Taken for 6 months to 1 year
- July 25, 2021
"I started this 7 mg along with 1000 mg of Metformin in August of 2020, and I have lost over 65 pounds. I was insulin resistant and could not lose weight regardless of my diet. I’m 56 years old, and this has been the easiest weight loss I have ever had, and I have done it all. I did begin with a low carb diet, but now I eat what I want in moderation. It has definitely helped with my appetite, and I feel full quickly. I am under a doctor's supervision and go monthly, and all of my numbers are great. It may not work for everyone, but for me, it’s been a lifesaver."
- Mis...
- Taken for 6 months to 1 year
- August 14, 2020
"Started Rybelsus when it first came out in October 2019. Took 3 mg at first and my glucose levels started to rise. Changed to 14 mg and was on that for 6 months. Glucose went very low - I was tired and weak. A1C went from 10.1 to 5.2. Changed to 7 mg and feel so much better, glucose levels are still within normal limits. I've had no side effects and great results. I do take this with 5 mg of Glipizide - once a day. Have tried many diabetic drugs and Rybelsus has worked the best. I've had a slight weight loss... under 10 lbs. So glad I tried this drug. It's a winner in my book."
- Psy...
- Taken for less than 1 month
- September 28, 2020
"Started on Rybelsus 20 days ago after I went in to see my doctor and my A1C was 11. This is while I was also taking pioglitazone and 2000 mg of metformin. After being on it for only 20 days, it has brought my blood sugar average down from 269 to 131. My 14-day glucose is 114, and my 7-day average is down to 109. I am hopeful that my next A1C reading will be 5.6. I did notice a little looser stool when I started it, but nothing worse than when I started Metformin. So far, so good. My only complaint is how expensive it is! I may not be able to continue it because of the cost."
Learn more about Diabetes, Type 2
- Diabetes Medications and Alcohol Interactions
- FDA-Approved Weight Loss Drugs: Can They Help You?
- OneTouch Blood Glucose Meters
- Side Effects of Weight Loss Drugs
- Top 10 Diabetes Treatments You May Have Missed
- What is Insulin Resistance?
- Which Drugs Cause Weight Gain?
Care guides
- Diabetes and your Skin
- Diabetic Gastroparesis
- Diabetic Hyperglycemia
- Diabetic Kidney Disease
- Diabetic Neuropathy
- How to Draw Up Insulin
- Hypoglycemia in a Person with Diabetes
Medicine.com guides (external)
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- En español
"This med Rybelsus is awesome. It has helped me bring my A1C down to 5.1 from a high of 9.7. I first started with the 3mg and am now on the 14mg. Been on this med since March and while I did experience some nausea and mild upset stomach, it went away after about a week. It has also helped me lose 50 lbs as well. I also take it with metformin. I should be the poster child for this drug... even though I'm 50."