Skip to main content

Rybelsus for Type 2 Diabetes User Reviews (Page 2)

Reviews for Rybelsus

Commonly mentioned side effects
  • Psy...
  • Taken for less than 1 month
  • September 28, 2020

"Started on Rybelsus 20 days ago after I went in to see my doctor and my A1C was 11. This is while I was also taking pioglitazone and 2000 mg of metformin. After being on it for only 20 days, it has brought my blood sugar average down from 269 to 131. My 14-day glucose is 114, and my 7-day average is down to 109. I am hopeful that my next A1C reading will be 5.6. I did notice a little looser stool when I started it, but nothing worse than when I started Metformin. So far, so good. My only complaint is how expensive it is! I may not be able to continue it because of the cost."

10 / 10
Was this helpful?YesNo
68 Report
  • Ash...
  • May 12, 2021

"My endocrinologist prescribed this to help with PCOS. I weighed 211 lb and started on 3 mg and lost 6 lbs while walking for 2 miles a day most days for a month. I was bumped up to 7 mg, but insurance wouldn't cover it, and I ended up gaining the weight back after trying Victoza and Byetta. My insurance changed, and my endocrinologist started me back on it at 7 mg since I already had Byetta in my system. During this time, I found out I have Ehlers-Danlos and was recommended to start weight lifting to help strengthen my muscles and lost 13 lbs in a little over a month, which I'm sure exercise has helped contribute. My menstrual cycle has been regular and on time for the first time in 4 years. I haven't had any major side effects other than a little nausea when I first take it in the morning and diarrhea, but I had that issue beforehand. I know a lot of people have said the side effects are terrible, but it hasn't been for me, and you should certainly give it a try. It's honestly been wonderful."

10 / 10
Was this helpful?YesNo
60 Report
  • Ali...
  • Taken for less than 1 month
  • August 16, 2020

"I have been exercising, dieting, counting every calorie, weighing food, and meal prepping. No weight loss and fasting blood sugar is still over 160 after 24 hours of fasting. I tried metformin, I got diarrhea, but no weight loss and no decrease in appetite. I need to lose 30 lbs and have lost 8 by skipping breakfast, having lunch, and skipping dinner some days. If I eat before 5 PM, I don't get reflux and I sleep better. I am having night sweats, but I'm 56, so I'm menopausal. I'm not taking hormones. I increased the dose to 7 mg and had diarrhea for 3 days, I'm now up to 14 mg on an empty stomach. No more diarrhea, and I have energy. I am 142 now and trying to eat healthy, but mostly eating no more than the size of my fist and staying as active as I can. I'm feeling cravings go away."

10 / 10
Was this helpful?YesNo
62 Report

Frequently asked questions

  • owl...
  • Taken for 6 months to 1 year
  • April 26, 2021

"I've been on Rybelsus for eight months, and I have lost about 34 lbs. I started on the 3 mg dosage, and after two months, moved up to 7 mg, where I have stayed. However, one of the major side effects is slowed gastric emptying, which can lead to extreme stomach pain if you make the mistake of eating too much in a day. After a couple of bad episodes, I had an endoscopy just to be sure nothing else was wrong - but ultimately, my gastroenterologist said that it's just the effect of Rybelsus."

8 / 10
Was this helpful?YesNo
55 Report
  • SSH...
  • Taken for 1 to 6 months
  • February 25, 2020

"I have been on Rybelsus for 2 months. I started on the 3 mg and did fine, no side effects, and actually felt more awake and focused. Then I went to the 7 mg and was very nauseous and vomited almost nightly. It felt like my food never digested. I apparently am pretty sensitive to this medication and since my blood glucose and A1C have been good, I am taking this every other day, which has lessened the nausea and discomfort. I have lost 6 lbs in the past month and that has been great because I needed that. So we will see how this continues, but I feel pretty good."

9 / 10
Was this helpful?YesNo
65 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • L0v...
  • Taken for less than 1 month
  • March 14, 2020

"Second day on Rybelsus 3 mg. I was too afraid to try it, but I'm glad I did. No side effects at all except for the loss of appetite. I will return and provide an update. I need to lose 60 lbs. I have tried Victoza and Invokana and got very sick within the first couple of days of taking them, so I hope Rybelsus is the answer for me. I exercise and watch my diet, but my glucose levels were still too high."

10 / 10
Was this helpful?YesNo
64 Report
  • JJa...
  • Taken for 1 to 6 months
  • April 29, 2021

"This is the first medicine I've used that has actually helped me lose weight. I take a bunch of psych meds that have packed on pounds (Seroquel). I started with the 3 mg titrating package and had slight heartburn for a few days. By the end of a month on 3 mg, I lost ~6 lbs. I had slight nausea at first on the 7 mg dose (after a month on 3 mg), but that faded. Now, after a month on 7 mg, I'm down a total of 14 lbs total (233 to 219). Before this med, I've been trending only upward for the past 4 or 5 years. I'm super stoked that I might be able to see under 200 lbs again in a few more months."

10 / 10
Was this helpful?YesNo
52 Report

More FAQ

  • Jer...
  • Taken for 1 to 6 months
  • June 20, 2023

"It was a disaster for me. My A1C used to stay between 7.5 and 8.5, and morning fasting readings were high, like 130 to 160. Increasing Glimepiride from 4 mg up to 8 mg didn't work. My doctor started me on 3 mg/day of Rybelsus. It caused constipation, upset stomach, and a lot of burping. But morning fasting readings came down to around 100, so I was tempted to try it out. After finishing the 3 mg dose for 30 days, I started taking 7 mg/day. My symptoms worsened: constipation, loss of appetite, noisy stomach, lots of burping, GERD, and weight loss from 152 lbs to 139 lbs in just about a couple of months. I could not afford to lose any more weight. I also saw some foamy urine indicating it was affecting my kidney function too. I stopped taking Rybelsus under my doctor's advice, and since then, the constipation is gone, the burping is gone, the appetite is good, and life seems back to normal. I still need to check on my kidneys for any issues since foamy urine is still there. The last A1C was 7.9."

1 / 10
Was this helpful?YesNo
28 Report
  • Bir...
  • Taken for 1 to 6 months
  • August 12, 2020

"Bad news: I started taking the 3 mg Rybelsus for 30 days, did well. Have been taking the 7 mg for the past 3 weeks, and I have had diarrhea, stomach bloating, nausea, and can barely eat anything or drink. Even the smell of food makes me sick. I am extremely exhausted and hate feeling like this. Calling doctor tomorrow. Good news: dropped A1C from 8.4 to 7.3 in 6 weeks and lost 10 pounds, and also cut back on my 24 hr insulin and fast acting due to not eating. — Is it really worth it though???"

3 / 10
Was this helpful?YesNo
58 Report
  • Cla...
  • Taken for 1 to 6 months
  • December 12, 2020

"I just got my A1C after 3.5 months on Rybelsus (one month at 3 mg and 2.5 at 7 mg), and I’m very excited that it’s dropped from 7.8 to 6.5! I have had some side effects - mainly stomach pain, gas, and occasional constipation - but the results are worth it. I haven’t had any significant weight loss, but my BMI was under 27 to start with, and because we had Thanksgiving recently, I normally would have gained a couple of pounds. If you have just started and are having side effects, try to hang in there. The first month was the worst for me."

8 / 10
Was this helpful?YesNo
49 Report
  • Rit...
  • Taken for 1 to 6 months
  • January 17, 2020

"For the first three weeks on this drug, I had oscillating constipation and diarrhea. I felt very nauseous and did not want to eat much. After upping the dosage, the digestive problems have decreased, but I still feel nauseous and don't have much of an appetite. I have been on it since November and have lost 16 lbs. with Metformin, diet, and exercise."

5 / 10
Was this helpful?YesNo
55 Report
  • Big...
  • October 7, 2020

"I started taking Rybelsus for weight loss. I was 326 lb. Now that I have been on it for a month, I have lost 8 pounds. I’m 318 lb currently. I have had absolutely no side effects. I’m a 6’1", 22-year-old male. I am not sure if that factors into anything. Anyway, tomorrow I’ll be starting to take 7 mg, then hopefully next month 14 mg, and so on."

10 / 10
Was this helpful?YesNo
47 Report
  • Car...
  • Taken for 1 to 6 months
  • March 19, 2022

"Using Rybelsus was a nightmare for me. I have insulin resistance, and my doctor wanted to bring my A1C down below 6. First, it caused me to gain 10 lbs while I was on the 3 mg. I thought once I started the 7 mg, the weight would finally start to come off. Nope. If that wasn't bad enough, I was lucky enough to experience one of the rare side effects... nerve damage. My left leg started feeling like I had sciatica. It got a lot worse from there. Nerve damage not only affects the damaged area but your brain as well. It took about 4 months before I began to feel normal. I had quit the Rybelsus as soon as I realized what was happening to me. My annual family vacation was ruined. I had an extra 10 lbs on me. I couldn't drive for a couple of months, and my brain was seriously affected. Oh yeah, and nerve damage is like pain I never felt before, and I've given birth twice. I'm glad for the folks helped by this. It sure didn't work out for me."

1 / 10
Was this helpful?YesNo
35 Report
  • mym...
  • Taken for 6 months to 1 year
  • September 17, 2021

"I was started on Rybelsus 3 mg in March and went to 7 mg in April. The first two months were an adjustment. It totally curbed my appetite. I have a feeling of being full most of the time. I have noticed I am eating basically half of what I did before. My A1c went from 7.2 to 5.8, and I have lost a little over 20 pounds. Even with insurance, it is a little expensive, but then I found the manufacturer coupon on the Rybelsus website, and that helps tremendously. So far, I am very happy with this medication."

10 / 10
Was this helpful?YesNo
37 Report
  • Cha...
  • Taken for less than 1 month
  • October 16, 2020

"I am on the 23rd day of the 3 mg dosage. Looks like most of the reviews have the same common denominator: nausea, bloating, diarrhea, and I’m about to add myself to the list with those same side effects. I’ve lost a few pounds, and my glucose numbers are dropping. I don’t like being too nauseous to want to eat, but underneath, I feel very hungry. I’m hoping this will resolve itself, and maybe it’s just an adjustment. Otherwise, I might have to rethink this."

8 / 10
Was this helpful?YesNo
45 Report
  • Nor...
  • May 23, 2021

"I started taking Rybelsus around March 10 or so. I did the 3 mg, the 7 mg, and now am on the 14 mg. I am still very nauseous, but I am trying to figure out the best way to take the medicine. I find that I eat half the food I did before. I don't have much of an appetite. What has also helped me (tremendously) is getting a Freestyle Libre - I am able to check my blood sugar throughout the day and can see my peaks during the day. I had not weighed myself until this week, I had lost 6 lbs. I am an avid exerciser, but that and the way I have been eating have not helped me lose weight. I am very glad to see that I am losing weight because I have not been able to lose anything despite the exercise. I never knew what diet control was until I got the Freestyle. I can't believe the difference. Can't wait to go back to the doctor and get my A1C. Thanks for sharing."

9 / 10
Was this helpful?YesNo
40 Report
  • Ano...
  • Taken for 1 to 6 months
  • March 28, 2025

"I started in 3 mg, now in 7 mg. My blood sugars have come down enormously, I have lost about a stone in weight after being on it for 4 months. You must take it first thing with just a dash of water, don’t eat or drink for half an hour. The side effects are a bit brutal but do die down, bit of constipation and food suppression. Feel better than I have in a long while on this tablet."

7 / 10
Was this helpful?YesNo
2 Report
  • Mik...
  • Taken for less than 1 month
  • June 16, 2021

"I am on week 2 with Rybelsus. I started week one with 3 mg. No side effects, no weight loss, slight nausea, and greater appetite. I need to lose 20 lbs, and instead, I am hungry all the time. Called my doctor. He told me to double up on the 3 mg, bringing it up to 6 mg. Still, no side effects, very slight nausea, but increased appetite. Ugh! I want it to work so much. I will stick to it and see what happens."

5 / 10
Was this helpful?YesNo
42 Report
  • Lir...
  • Taken for 1 to 6 months
  • July 25, 2020

"Unfortunately, I had serious issues with this medication, Rybelsus. If you have any gastro disease, please do not take it. It started okay, but initially, I developed symptoms: sore throat, trouble swallowing, burning, tight chest, nosebleeds. I felt like my breathing tract was on fire. I have a hiatal hernia, and unfortunately, the amount of acid reflux due to this medication was beyond anything I could tolerate. I tried for 48 hours till I broke and stopped. All symptoms went away afterward."

4 / 10
Was this helpful?YesNo
45 Report
  • ATQ...
  • Taken for less than 1 month
  • March 13, 2023

"I took my fourth dose of 3 mg Rybelsus this morning. I've followed all the directions, but it has been awful. I've been incredibly sick since the second day. I've been vomiting, nauseous, I've had a nonstop migraine, and every time I cough, vomit, sneeze, or gag, my entire upper body feels like it's being electrocuted. I emailed my doctor last night. Hopefully, I'll hear from her today. This is miserable."

1 / 10
Was this helpful?YesNo
25 Report
  • Ann...
  • Taken for 1 to 6 months
  • March 23, 2025

"I have Type 2 diabetes. I have been on this medication for about 5 months and have had significant improvement in my A1C. I started at 7.2 with an average blood sugar of 147. After 3 months, my doctor was well pleased my A1C had dropped to 5.2 and average BS 116."

10 / 10
Was this helpful?YesNo
2 Report
  • Ann...
  • Taken for 1 to 6 months
  • March 23, 2025

"I have type 2 diabetes. I have been on this medication for about 5 months and have had significant improvement in my A1C. I started at 7.2 with an average blood sugar of 147. After 3 months, my doctor was well pleased my A1C had dropped to 5.2 and average BS 116. I do have a slight issue of dizziness when standing up. Not sure if the cause could be blood sugar drops. I have a family history of diabetes and understand the damage it does to your body. I was on metformin for years and my A1C was never below 6.2. I stopped taking it after reading such bad reviews and would never take it again. I have been able to mostly control my levels with diet and moderate exercise by staying active. Currently 71 and have developed a huge sweet tooth. Sugar level was in the high 140s, so I knew I had to do something. My age goal is 110, lol, so time to get healthier. I have lost about 10 pounds in a good way. My decreased appetite has helped me control the food binges."

10 / 10
Was this helpful?YesNo
2 Report
  • Tal...
  • Taken for 6 months to 1 year
  • June 9, 2020

"I've been on Rybelsus for 7 months, my starting dose was 3 mg, then to 7 mg. After taking 7 mg for 4 months, my blood sugar began rising higher. I was following a proper diet, so not sure why this happened. Then went to 14 mg, and my blood sugars did great again for 3-4 months and did great, but now blood sugar is rising. Had nauseousness so bad at the start of each new dose increase, my Dr. gave me nausea medication that helped. I've lost 30#. Afraid at this point I'll have to stop and go to insulin. My A1C has gone down, but not enough. Disappointed. Wish Rybelsus would continue to work for me."

8 / 10
Was this helpful?YesNo
40 Report
  • TN ...
  • Taken for 1 to 6 months
  • October 5, 2020

"I've been taking Rybelsus, along with metformin and Farxiga, for over 3 months. I had some minor diarrhea/constipation with the 3 mg that worked itself out quickly, but I lost over 5 lbs and A1C went down over 1 pt (8.3 to 7.2). Just started the 7 mg dose 5 days ago. So far, the diarrhea is a lot worse, and I'm having a lot of dizziness/nausea/fatigue/headaches, but I'm hoping it'll stop soon. I seem to start feeling worse about 5-6 hrs after taking the pill, so I'm sick in bed for hours in the afternoon and evening lately. Not good, as I'm a disabled housewife with two special needs adult children who depend on me. Not sure how someone who works a 9 to 5 job would be able to handle this transition period. If it doesn't sort itself out within a couple of weeks, I'll call my doctor. One tip: keep some saltine crackers and eat a few every hour or so. I know, against diabetic diet, but that and plenty of water help the nausea."

8 / 10
Was this helpful?YesNo
38 Report
  • Gra...
  • Taken for 1 to 6 months
  • August 26, 2022

"I have pre-diabetes and obesity and started on the 3 mg dose for the first month and then moved to 7 mg. I was very nauseous and found I could eat very little. I had no appetite. Great for weight loss, but I felt really bad. Maybe two weeks into the 7 mg dose, it was a little better. Then the doctor wanted me to move to 14 mg. I don't like to throw up, and it became too much for me to tolerate. I asked to go back down to the 7 mg dose and have done fine on that ever since. Definitely still keeps appetite in check. Five months in, and I’ve lost 35 pounds. Also showing improvement in my blood sugar levels."

8 / 10
Was this helpful?YesNo
24 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.