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Ozempic User Reviews & Ratings

Ozempic has an average rating of 6.4 out of 10 from a total of 1,095 reviews on Drugs.com. 50% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Ozempic

  • Zell
  • Taken for 6 months to 1 year
  • March 29, 2021

For Diabetes, Type 2 "I started Ozempic 9 months ago. At the time, I was a little over 200 lbs and was taking 1000 mg of metformin daily. Metformin had worked for me for almost 20 years, so I didn't expect that it had suddenly stopped working. For 3 years, I gained weight even though I worked out, and I thought it was just my appetite out of control. One random day, I realized my metformin was the problem. I saw a new doctor who prescribed Ozempic. What a miracle! 9 months later, and I’m down 40 lbs, my A1C dropped from 8.1 to 5.6, and I have virtually no symptoms from the drug other than fullness. The symptoms in the beginning did not last long either. Nausea, headache, fatigue...all cleared up within a week or 2 each time my dose was increased. It can cause what feels like constipation, but for me, it’s just that I simply haven’t eaten enough. This drug feels too good to be true. I’m so pleased with my experience so far!"

10 / 10
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  • Kitkat
  • Taken for 1 to 6 months
  • July 20, 2021

For Diabetes, Type 2 "I'm a 54-year-old female whose A1C was 8.3 at the end of March. So, after 4 months on Ozempic, my A1C is now 6.3, and I've lost 34 lbs. Definitely curbs my appetite, and I have been logging my food. My side effects have been minimal - a little nausea in the beginning and constipation. This med has been a game-changer for me. My hope is that many others will have the same results I have."

10 / 10
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  • Anon
  • Taken for 1 to 6 months
  • May 19, 2020

For Diabetes, Type 2 "I was terrified to take this after reading some of the reviews online, but I have to say I am so happy I started this drug. I've followed others' suggestions about injecting the drug into my upper thigh and not my abdomen. I was on a 0.25 dose for 4 weeks, then moved to 0.5, and that's what I currently take. My appetite has decreased SIGNIFICANTLY. I was addicted to eating junk foods, and I simply cannot eat them anymore; my stomach cannot handle them. I get full after eating one properly sized meal, and it keeps me going for most of the day, only having a snack like 1 apple in the evening. Side effects were mild for me; I had some constipation, but I started taking fiber supplements to help with that. I have been on the medication for 7 weeks now, and I'm down 10 lbs, and I feel great. Make sure your doctor gets you to increase the dose slowly, inject into your thigh, and be ready to make better dietary choices when starting this drug. I truly believe it saved me from morbid obesity."

10 / 10
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Frequently asked questions

  • Conce...
  • Taken for 1 to 6 months
  • February 1, 2021

For Diabetes, Type 2 "I started Ozempic in late December at 0.25 injection. I also take 500mg metformin per day. Soon after I started Ozempic, I had decreased appetite and my sugars improved, but I had reflux, gas, bloating, nausea, and diarrhea. After 4 weeks, I started 0.50. 2 weeks in, I have bouts of painful constipation then diarrhea, nausea, bloating, gas, reflux, and cramping. I've almost vomited a few times. When I eat, it feels like the food just sits and sits, barely moving through my gut. My doctor wants me to stick with it, saying that these side effects usually improve, but it's been pretty miserable. I'm thinking I'm going to stop taking it. While Ozempic has been effective in regulating my sugars and losing weight, I don't think it's worth the suffering that I've been enduring on this medication. I understand that studies showed it causing thyroid cancer in mice, but no one knows if it causes thyroid cancer in humans. I don't want to be the guinea pig the drug makers use to find out it does."

5 / 10
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  • Margie
  • September 27, 2020

For Diabetes, Type 2 "I was put on Ozempic after taking Glimepiride for several years. I started on 0.25mg, then onto 1mg. I started having the nastiest burps ever, then diarrhea 3 to 4 times a day. After 3 months, I went to a gastroenterologist and was diagnosed with gastroparesis, a side effect of Ozempic. I have all the side effects - nasty, offensive-smelling burps, eye floaters in both eyes, bad diarrhea, stomach pain, and now this disease that has caused precancerous cells. Yes, my appetite has decreased, I have lost 15 lbs in 3 months, and my numbers are good. But it's not worth being sick every day. I just found out my daughter is going through the same exact thing. So, take it at your own risk."

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Are you taking this medicine?

  • JEano
  • Taken for 1 to 6 months
  • August 26, 2020

For Diabetes, Type 2 "I have been taking Ozempic for 4 months to reduce insulin resistance (caused by polycystic ovary syndrome). The medication has significantly reduced my appetite. I have had a few minor side effects - a stomach cramp here, an episode of diarrhea there...but nothing at all significant. My weight went from 151 (BMI 25.9) to 133 three months later (BMI 22.8). I honestly could not be happier."

10 / 10
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  • Snowc...
  • Taken for 6 months to 1 year
  • July 16, 2019

For Diabetes, Type 2 "Side effects are mild for me, but it really decreases your appetite. Initially, I could only tolerate fresh fruits and vegetables. I took this as an opportunity to change my lifestyle. I eat healthier and avoided sugary drinks. I lost a total of 40 lbs. in 6 months. A1C dropped from 7.3 to 5.4. Dress size dropped from 14 to size 4. I am no longer on daily insulin, BP meds, and cholesterol meds. All labs are normal. This medication is my lifesaver."

10 / 10
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322 Report

More FAQ

  • Mimi
  • Taken for 1 to 6 months
  • July 7, 2023

For Weight Loss (Obesity/Overweight) "Since my first injection, I have felt utterly dreadful. The nausea is one thing, but I have constant fatigue that prevents me from leading my normal life. I know it suppresses appetite, but I don’t have ANY appetite at all and cannot face food. I know if I eat, I will feel a bit better, but it’s impossible. I actually feel like I’ve been drugged. Yes, the ‘food noise’ has gone, and I no longer overeat or binge, but I feel like everything is suppressed - like I’m on a strong drug. I did 4 weeks at 0.25 and have just done one week at 0.5, but I can’t do this anymore. I feel utterly dreadful. I am so pleased it’s helping so many people, but more research is needed into why some people just can’t tolerate it."

3 / 10
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  • Aila
  • Taken for 1 to 6 months
  • January 4, 2021

For Cardiovascular Risk Reduction "I went on Ozempic for weight loss after being told by a friend of mine about it - she started at 280 lbs and lost 60+ pounds. My whole life I’ve always been about 130 pounds, and then I rapidly gained 50 pounds within about 2 years. I started taking Ozempic at 182 pounds (I’m 5’4) and 6 months later I am down 25 pounds and continuing to lose. I could not recommend this drug more. It INTENSELY reduced my appetite and obsession over food. Aside from some occasional nausea (maybe once every 2 weeks), and some diarrhea, nothing that I can’t handle, the drug has been pretty great. This is only my experience though!"

10 / 10
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  • Chris
  • Taken for 1 to 6 months
  • July 11, 2021

For Diabetes, Type 2 "I suffered from - Loss of appetite - Exhaustion - Nausea - Vomiting (once a week, usually 2 days after my injection) - Low blood sugar events (probably caused because I just had no appetite). When I spoke to my pharmacist, she encouraged me to try to hang in there, telling me it would get better, and it finally has. I was not expecting it to take over 3 months though. My readings are all good, and I've lost 28 lbs, so there were benefits to sticking it out, but it was hard. I had decided that I would continue to take the medication until my next appointment, and if things were still bad, I would tell the doctor that I no longer wanted to use it. Things are better, and my appointment is next week."

5 / 10
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  • Nw272...
  • Taken for 1 to 6 months
  • June 20, 2021

For Diabetes, Type 2 "Started April 1, 2021, on Ozempic low dose. 3-week intervals it was increased. Side effects were constipation (went on laxatives to help), pain in my back (severe), bloating. Week 11 increased to 1mg, the side effects were major bloating, diarrhea, sounds in my stomach (crazy), nauseous, feeling under the weather. My appetite has decreased to the point that I only eat 2 meals a day that are small. My sugar levels have decreased from 7.1 to 5.2 A1C. I’ve noticed that I have been kept awake some nights like I’m nervous for some reason. In the first 3 weeks, I’ve lost 15 pounds. Haven’t checked since I want to wait but can feel a difference. The pains in the stomach are really uncomfortable, and the bloating I will try gas-x for relief. When I try to eat more than I should, my body tells me that I’m full. If I go beyond that point, I get severe pains in the stomach for hours. But depends on what I eat. Going to stay with smaller portions/healthier foods."

8 / 10
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  • Calez...
  • Taken for 1 to 6 months
  • September 21, 2019

For Diabetes, Type 2 "Since starting Ozempic, all my numbers have gotten considerably better. I did have nausea for several months, but I took medicine to counteract the nausea, and now I’m feeling much better. My appetite has been cut in half. I have lost a total of 40 lbs so far, and I couldn’t tell you the amount of inches I have lost; it seems that I lost inches first and then weight. I have started going to the gym. My advice to anyone starting Ozempic is to stop eating as soon as you get that first feeling of being full; don’t try to finish the plate just because you don’t want to waste food because it will make you sick if you force yourself to eat it all."

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  • Kay
  • Taken for 1 to 6 months
  • August 16, 2020

For Diabetes, Type 2 "With an A1C approaching 11, it was time to try something else in addition to Novolog and Tresiba, so my doctor added Ozempic. I also quit all alcohol and became a vegetarian. The first 3 weeks at 0.25 left me with a decreased appetite, nothing severe. The pounds started dropping off; fast forward 3 months and I am 22 lbs lighter. I love Ozempic, no bad side effects, and my insulin needs have decreased (not gone away); best of all, my A1C was 7! A lifestyle change helped a lot, but I credit Ozempic for many of these positive changes."

10 / 10
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  • Dotzer
  • Taken for less than 1 month
  • April 5, 2023

For Weight Loss (Obesity/Overweight) "I'm a 38-year-old man with type 2 diabetes and overweight. I was on metformin for three years and followed a good diet and exercise regime, but I couldn't lose weight. Although my blood sugars were perfect on metformin, weight was my issue. My doctor prescribed me Ozempic 0.25 mg, and I was very worried about the side effects. However, I started it recently anyway and injected it in the upper thigh once weekly. I had no issues other than constipation, which I overcame with laxatives and increased water intake. My appetite was reduced by 90%. I used to overeat, but now I can only manage two small meals a day. It's really working so far, but it's still early days. I'm in Ireland, and it costs €150 a month for four injections, which are covered by my medical card. I'll provide an updated review in three months to report how it has helped me lose weight on the scales."

9 / 10
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  • Kris
  • Taken for less than 1 month
  • July 2, 2023

For Weight Loss (Obesity/Overweight) "This drug affects everyone differently, but for me, the side effects were too bad, and I had to stop after 2 weeks. It totally worked by killing my appetite and making me feel full, and after the first week, there were days I didn't even want to eat at all. I lost about 8 pounds in two weeks, which is great. However, during the 2nd week, I got the worst upset stomach of my life and almost went to the ER. I had intense diarrhea for an entire day, along with nausea, the chills, a swollen stomach, and then sweating. I had to take a sick day from work because I was also dizzy, and my heart was racing. It finally subsided about a day and a half, but it scared me so badly that I stopped taking the drug. Now I understand why it has a black box warning. I'm happy for the people who can use this without bad side effects. For me, I have a young child and demanding job. I can't go around with symptoms of food poisoning and try to act like I’m ok."

4 / 10
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  • Annie...
  • Taken for 6 months to 1 year
  • September 9, 2019

For Diabetes, Type 2 "Hi! Have been on Ozempic for 10 months. The first 3 months were very difficult with strong side effects. Mainly constant, but low level, nausea, occasional vomiting, and diarrhea (especially two days after the injection). However around month 3 the nausea and diarrhea subsided greatly and my appetite returned. I had lost weight very quickly (42 lbs in 3 months due to not really eating much). Had to take supplements for a while but am now eating well. The rapid weight loss led to telogen effluvium, a temporary hair loss condition. (I shed A LOT but never showed any baldness or anything). Currently, my weight is still down (I was taken off my blood pressure medication!), my blood counts are perfect, my hair is getting thick, and I eat normally. I now experience virtually no side effects. Really, really, glad I stuck out the side effects at the beginning."

7 / 10
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  • Melissa
  • Taken for 6 months to 1 year
  • February 25, 2021

For Cardiovascular Risk Reduction "I have been on Ozempic for weight loss for 10 months and I have lost 66 pounds!! This drug has been amazing. At first I had a few side effects which included nausea and constipation but they did resolve. I noticed almost immediately how much better I felt on this drug. Not only was my appetite significantly decreased I felt better overall sort of like my metabolism was more even and my body utilized what I ate more efficiently. I lost my work insurance in November and also lost the coverage for the Ozempic. This is the only downfall. I do have private insurance through health partners but not one cent is covered by them. The price per month is around $800. With results this good all insurance company’s should be covering the cost 100% because it will save them millions, billions, even trillions possibly in the future. If they were smart they would get behind this drug."

10 / 10
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  • Jess
  • Taken for 6 months to 1 year
  • March 2, 2022

For Cardiovascular Risk Reduction "Been taking ozempic since August 2021 (so just over 6 months now) I’m taking it for help losing weight, currently at the 1mg dose with no negative side effects. First month of taking ozempic is a challenge. You will probably feel like crap, but once your body gets used to it the medication works wonderfully. I’ve lost 45 pounds in 6 months, 15% of my body weight. As long as you calorie count this medication will definitely help. For me it curbs my appetite drastically and stops “impulse” buying junk food. It also helps with blood sugar, unlike with dieting alone I don’t get “hangry” which is amazing. Needle is tiny and does not hurt at all."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 27, 2023

For Weight Loss (Obesity/Overweight) "I am just completed my first 2 weeks. I want to lose 35-40 pounds. In the past year, I have gained a pound a month and have been steadily gaining weight every year for the past 7 years. Have previously tried weight watchers, increased activity, and calorie watching, and the only time I lost any weight was on less than 1300 calories a day. The first week I lost 3.5 pounds, more weight than I had lost in the past 5 years even with calorie restricting. I inject in alternating thighs on Friday nights, just in case I have symptoms I can recover without work demands. I have always been gassy so cannot comment if there is a difference in the amount. I am noticing increased chest tenderness and muscle spasms. Restless legs are a thing! Taking magnesium once or twice a week also helps with moderate constipation. Reduced appetite, reduced sugar craving but no impact on munchies. Makes easier to choose healthier choices. Overall happy with almost 5-pound weight loss in 2 weeks. Minimal side effects and well worth it."

8 / 10
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  • Tanya
  • Taken for 1 to 6 months
  • May 12, 2022

For Cardiovascular Risk Reduction "I have been taking Ozempic Since March 12, 2022. I started at the .025 dose for 4 weeks I had a little nausea but nothing serious and some constipation. Have now been on the .050 dose and have very little appetite and no other symptoms have remained other than occasional constipation I have to remind myself at times to eat. I have more energy then I have had in years and feel so much better in my clothes. Since March I have lost 25lbs. This has been a life changer for me as I feel so much better I am still 45 pounds from my goal weight but this drug has definitely helped me. I give the shot in my thighs as I have read many comments on here to do so for less symptoms and I believe that is why I have done so well."

10 / 10
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  • NursD...
  • Taken for 1 to 6 months
  • July 15, 2023

For Weight Loss (Obesity/Overweight) "Ozempic for weight loss is AMAZING! I have tried everything for weight loss since 1985. Ozempic by far is a miracle for me. It immediately blocks cravings, appetite, and thoughts about food! I started June 2, 2023 and today, July 13, 2023, I lost 22.3 lbs. This is a 6-week success story! I took 0.25 for the first week and then 0.5 weekly on Sundays. I have stayed with Weight Watchers, mainly selecting 'free foods'. If you are eating out with friends this summer, remember that rich, high-fat content foods will give you immediate abdominal distress (cramps, diarrhea). So, I've learned to go through restaurant menus and find something less distressful to eat so that I can enjoy time with friends and family. I have Zofran for nausea, but for me, the nausea passes and I do not use anything for nausea. Stay active at least walk! It's free! Keep drinking water and add a packet of electrolytes due to this extreme heat this summer! Check-in with my doctor on a regular basis."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • May 8, 2023

For Weight Loss (Obesity/Overweight) "I was prescribed Ozempic for weight loss in Nov 2022. I started on .25 mg for one month. I found it slightly suppressed my appetite and the side effects I had were awful heartburn, constipation, and sulphur burps. Sometimes I felt nauseous. I decided to stick with it anyway and increased to .5 mg after one month. The symptoms were the same but add in fatigue. A month later I bumped up to .75 and the burps, fatigue and heartburn subsided. I went to 1 mg 2 months later and all symptoms disappeared. I started at 192 lbs Nov 15th and as of May 1st I weigh 152 lbs. I found my sugar cravings disappeared once I started taking 1 mg. Up until then I still craved sugary foods. I lost all interest in greasy food ( fries, anything deep fried etc) from .5 mg and up. I personally love Ozempic. The side effects at the beginning were worth it for me but from the sounds of it, mine weren’t that bad. I have never once thrown up."

10 / 10
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  • Retired...
  • Taken for 1 to 6 months
  • February 25, 2020

For Diabetes, Type 2 "Take my comments for what they are worth since I changed many things in my life at the same time...but.. I think Ozempic is great. After 5 months reduced my A1c from 9.7 to 5.9. Lost almost 25 pounds. Am at .5mg and it has drastically reduced my appetite. Between smaller stomach and this drug often push my plate away before finishing, rarely desire for dessert. Little to no side effects overall. Some stomach issues like constipation, bloating but can’t rule out dietary changes being the cause also. Went on a low carb diet and really stuck to it for once and increased exercise a lot. Use of the Freestyle Libre Sensor really really helped too! Being able to learn how things effect your blood sugar in real time is a great motivator to do the right thing, combine carbs with protein etc Hoping to lower other meds I am on when I see my Doctor next month. Once a week tiny needle (virtually pain free) is a far better system than pills everyday."

10 / 10
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  • Laurel
  • Taken for 1 to 6 months
  • April 1, 2020

For Diabetes, Type 2 "I have been prescribed Ozempic for weight loss secondary to type 2. I got nauseated with some loss of appetite at .25 mg dosage and adapted to it over a month. Lost 9 lbs in that month. I increased to 0.5 mg last Friday (it is Tuesday), and I am miserable. Non stop nausea, burping, some pain in stomach, constipated. I feel miserable. I am worried about the stomach pain being pancreatitis starting so I am increasing my water. I haven't eaten in two days. I will not continue with this drug as I thin this just cannot be a good thing to do to ones body."

3 / 10
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  • Pat
  • July 19, 2019

For Diabetes, Type 2 "Started taking Ozempic for pre-diabetes and insulin resistance. This is first medication I've ever taken for diabetes. A1c was 5.7. I increased dose quickly at doctor's recommendation if little to no side effects occurred. First dose 0.25 in office. Second 0.5 a week later. Third dose at 1.0 a week after that. Only side effect I have is mild nausea. Appetite has disappeared and I eat only when hungry and much smaller portions. Serious bloating when I eat too much, which is a great deterrent. Been on medication 4 weeks overall, 2 weeks at 1.0, weigh dropped from 305 lbs. to 295 lbs. Still a little lethargic but I was very lethargic before starting medication. I feel like this medicine is a game changer for me. I love not thinking about food all of the time, only eating when hungry and not for pleasure, and losing weight. Will retest A1c in 2 months. Hopefully the weight loss continues and I caught the A1c level before it turns into full-blown diabetes."

10 / 10
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87 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.