Zoryve for Plaque Psoriasis User Reviews

• deb...
• Taken for 1 to 6 months
• July 23, 2023

"Using it for two months, plaque psoriasis on legs and elbows for over 10 years with sporadic spots here and there at any given time. My elbows are now clear, and my legs are 80 percent clear. I feel like this is a miracle medicine, as my psoriasis was never-ending on steroid ointments. I have had no side effects on this medicine, and applying once a day. I am 65 years old, and the plaques on my legs were affecting my mental health as well. Happy to say this medicine is working for me."

• Sus...
• Taken for 1 to 6 months
• September 15, 2023

"I have psoriasis on both my hands and I used Zoryve for approximately 3 months, during which time the psoriasis improved immensely. I had no noticeable side effects and was extremely happy with the results. Sadly, during the three months I was using Zoryve, I turned 65 and went on Medicare. When I went to refill my prescription, it was going to cost me over $500. Apparently, they don’t offer the discount/coupon price to people on Medicare, so I am no longer using the medication and the psoriasis flared back up within a month. There are a lot of things in this country that need fixing - prescription drug costs need to be at the top of the list! I’m not sure why the drug companies offer the discount to people with non-government insurance and not vice versa, but I'm hoping there is some relief."

• Par...
• Taken for 6 months to 1 year
• April 4, 2024

"Applied this daily for 6 months to deal with ulcerated plaque psoriasis on hands. Had previously used Lamisil/Micatin, which worked up to a point, but could not clear plaque. Zoryve works!!!! Like nothing else! Another review said, 'miracle drug', and I would agree. Plaque is now mostly cleared. Zoryve melts skin to get at subcutaneous plaque, which other medications could not do. Also, it's VERY expensive. The maker has a program to give you the first tube for free, but after that, it costs $300/tube in Canada. It's expensive, but it works. It's REALLY expensive but it REALLY works."

• Nan...
• Taken for 1 to 6 months
• November 27, 2023

"I had tried other prescription lotions for my plaque psoriasis on my face with limited or no success. With Zoryve, I noticed improvement within days with daily use. My facial skin was totally stable within 3 weeks. Unfortunately, I suffered the side effects of daily low-grade headaches, nausea, and diarrhea, and interruption with my sleep. All symptoms decreased with time but did not disappear. I am taking a short break right now to alleviate the nausea and sleep interruption. As an aside, Zoryve did not work on my elbows."

• Mr ...
• Taken for 1 to 6 months
• July 31, 2023

"Within two weeks, 80% improvement to severe Psoriasis. Within 2 months, virtually clear - absolutely amazing response as I was on steroids for years and concerned about using a biologic. Only issue is it appears to reduce my appetite, which I am fine with. Takes time for skin color to fully return, but I am very happy. Patient in Canada."

• Mic...
• Taken for 6 months to 1 year
• September 30, 2023

"56-year-old, I've been taking it for 8 months (since February 2023). The cream is expensive without insurance, $900. It's still a new drug, and insurance would only pay $300 (BCBS). That being said, the medicine is incredibly effective. I suffer from psoriasis on my face and have been using steroid creams since 2006, but it constantly got worse and really started affecting my mental health. The medicine has almost completely cleared up my face, around 80-90%, after the initial month of daily use. I scaled back to using it every other day, which has helped keep acne to a minimum. Now the manufacturer offers a card that reduces the cost of the medicine to as low as $25 for 12 months. I've used mine for 8 months, but today they are not honoring the refills and I don't know why, so I can't afford the medicine at $600. I knew at some point (after 12 months) the discount would end, so I've been rationing my use. I have not been slathering it on, instead, I've been targeting specific areas, and it's worked out."

• Anonymous
• Taken for 1 to 6 months
• June 10, 2023

"The physician gave me a sample and a prescription to fill. The medication worked wonderfully, very easy to use. When I went to pick up the prescription, I could not afford it. It was so cost prohibitive. So I was unable to continue using."

• Sma...
• Taken for less than 1 month
• March 26, 2024

"I have had an extremely itchy rash on my shins for almost 4 years and nothing has helped. I was prescribed Zoryve cream by a new dermatologist I saw and have been using it for about a week now. It has helped a lot with the itching, and the rash has diminished in size. However, I have had a headache and stomach ache the past 2 days; I do not know if it's from the medication or if I have caught a bug."

• Ion...
• Taken for 1 to 6 months
• June 13, 2023

"After an initial flare following scraping of skin on the right shin treated with clobetasol steroid, secondary flares of white dots and rough areas appeared on the right and left knees. Tertiary flares later appeared on forearms after slight scraping wounds. Later, a fourth series of flares occurred on both thighs and in the groin and perineum area. Application of Zoryve ended these flare events within two weeks, and subsequent less serious limited flares were terminated within one week. Now, six weeks after my initial psoriasis event, skin has healed well in all areas. There may be a tendency for skin to thin in areas recently treated, as two minor scrapes have created torn areas that heal within a week."

• Itc...
• Taken for 1 to 6 months
• November 15, 2024

"I’m happy to see this worked for so many people. I had some success with the foam clearing up scalp psoriasis, but the side effects I experienced weren’t worth the 50% improvement. Constant nausea and headaches after using the foam for 3-4 days. It would take 3 days to feel good again. Tried just using it every third or fourth day… still experienced side effects. So I’m done with this."

• Lis...
• Taken for less than 1 month
• June 6, 2024

"Amazing. I tried 4 different prescription creams, light therapy for 15 months, and two different systemic (pill) drugs. Nothing was working for me and my hands were in constant pain, though the light therapy lessened the itching. One week using ZORYVE and I saw dramatic improvement. After 3 weeks, my skin was clear. Too bad it is so expensive."

• Bar...
• Taken for 1 to 6 months
• January 10, 2024

"I'm truly amazed. My teen daughter has been in a psoriasis flare for months. We've tried steroid creams in the past and they always made it worse. I was hesitant and fearful to try Zoryve. We got a few samples from her dermatologist. I could not believe how fast it cleared up her ears and side of her face. Her elbows have taken a little longer. Absolutely no side effects noticed."

• tra...
• Taken for less than 1 month
• December 10, 2023

"I received samples from the doctor because she did not think insurance would pay. To our surprise, it was paid for. After the first couple of days, the scaly skin became soft and the skin feels smooth."

• Wil...
• Taken for less than 1 month
• December 16, 2023

"My doctor gave me a sample tube and I used it the next day. It seems to have made my small amount of plaque go away. Pretty impressive so far. Haven't had any noticeable side effects yet. Only been using it for about a week."

• Dav...
• Taken for 1 to 6 months
• February 18, 2024

"I have occasional breakouts on my face. I was prescribed many creams that helped but not 100 percent. My doctor then prescribed Zoryve and it worked immediately. I only use it when I get a breakout and it works quickly within days and eliminates the entire redness and symptoms. I cannot express enough how comforting this cream is to my self-esteem and appearance. Awesome product but it is very expensive."

• Wor...
• Taken for less than 1 month
• January 31, 2025

"I have been dealing with plaque psoriasis on my scalp for over 15 years. After just 4 days, Zoryve foam completely cleared it up, and I was thrilled! On day 9, and for the past week, I have had diarrhea, other GI issues, and some random headaches. Had no idea this was a common side effect of this medication until I researched it online. Very disappointed. Not worth the side effects for me. Cortizone solution has helped in the past, but not nearly as effective as Zoryve. For anyone out there with scalp psoriasis that can't tolerate the side effects, I have found that hair oils help greatly, but it does take time and effort to use."

• mar...
• Taken for 6 months to 1 year
• July 8, 2024

"Gets rid of psoriasis in skin folds, comes back after a few days to a week. I've been using it back and forth with clobetasol, not at the same time, just every few days one and when it comes back, I use the other. It has less side effects than a bunch of other creams I have used, but may give you a headache or make you red for about a day. Pretty much most of these creams available make me red."

• Pea...
• Taken for 1 to 6 months
• June 25, 2024

"While this did not completely eliminate the psoriasis around and in my ears and hairline, it did help. It has caused zero negative effects. However, it is way too expensive for me to continue with it when what I have runs out."

• Anonymous
• Taken for 1 to 6 months
• September 2, 2023

"Have struggled with plaque psoriasis for years on my fingers and hands. This has taken 90% of my symptoms away. I have gone from wearing exam gloves (I work in a government office) at work to only using them when my hands are going to be wet for prolonged periods."

• Lyn...
• Taken for 1 to 6 months
• January 18, 2024

"I was recently diagnosed with plaque psoriasis. The skin on the palms of my hands was cracking and bleeding, and it was very painful. It took a few months to find the right medications. Zoryve has been a game changer. I use it daily. I also have had Skyrizi injections at the same time, so I'm not sure if it's the combination of both medications that is reducing my symptoms. My skin is almost normal now."

• Anonymous
• Taken for 6 months to 1 year
• September 22, 2024

"Makes a huge difference for psoriasis, completely stopped all the plaques behind my ears. However, it has caused chronic UTIs, which stubbornly resist antibiotics, and I will need to work with my derm and urologist to see what I should do next."

• Pat...
• Taken for 1 to 6 months
• December 17, 2023

"I have been using it for a month and a half and my psoriasis has cleared up completely. I have had minor side effects of urinary incontinence, but it's definitely worth the inconvenience to finally have my psoriasis under control."

• Ace...
• Taken for 1 to 6 months
• August 26, 2024

"I have been taking this in addition to my biologic treatment, Skyrizi. I don't think it's any better or any worse than other topical medications. I have been taking Clobetasol for years with similar results. For me, it keeps the itch down, but is not curative of the plaques."

• Sik...
• Taken for less than 1 month
• November 4, 2024

"Started using my Zoryve about a week ago for plaque psoriasis... Behind my ears, it helps with the itching and redness, however, it still has a continuous buildup/flakes. The first of this cream, thought it would get rid of the entire psoriasis... OVERNIGHT."

• Lau...
• Taken for less than 1 month
• September 28, 2024

"My dermatologist prescribed Zoryve for a patch of dry, itchy scalp that I had been dealing with for months. Within 3-4 days of use, the dry patch and white scales were completely gone. I had tried other options, but nothing worked. Very easy to use. I put it on at night before bedtime (the foam). Have zero side effects. Highly recommend this effective product. I can finally wear dark clothing again without fear of white flakes all over my shoulder!"