Skyrizi for Plaque Psoriasis User Reviews

• Anonymous
• Taken for less than 1 month
• November 9, 2020

"In October 2020, I took my first starter dose of Skyrizi. Within one week, I noticed my skin stopped flaking and started clearing up. After four weeks, my skin is almost cleared up. My body was 80% covered with plaque psoriasis. In November 2020, I will be taking my first full dose. I am very happy with the results. The only side effect I have noticed is urinating more than normal."

• mmi...
• Taken for 1 to 2 years
• September 8, 2021

"Been taking Skyrizi for more than a year now after failing on several other biologics, systemics for plaque psoriasis. Also went onto this medication with high blood pressure and heart issues and long COVID symptoms. It cleared me within 4 weeks, and I would say has the least amount of side effects out of any other biologic systemic I have taken. It also seems to control other miscellaneous inflammation, and I have not become immune to it quickly, unlike other medications. Not a single lesion has returned, I am 100% clear from having 20% severe coverage prior. I did get pneumonia recently, unfortunately for the 4th time, but antibiotics cleared it within a week. You do need to watch for infections, if you are not getting better on your own, see a doctor. This will happen on any biologic or systemic as it's my 4th time going through that. After what I have experienced, Skyrizi's benefits outweigh the risks, and in my opinion, would be the least risky internal treatment for psoriasis."

• MJP...
• Taken for 1 to 6 months
• November 29, 2022

"I've just had my 3rd dose of Skyrizi, and I couldn't be happier. I've had psoriasis for over 60 years, and I figured it was about time for me to get a break. My plaques were mostly mild until I turned about 55. Then they just started appearing everywhere, to the point where all I was thinking about was how to get rid of them. I'm a very healthy person -- I exercise daily, don't drink alcohol, don't smoke, and I'm not on any medications at all. But no matter what, the plaques just kept coming. I resisted medication for years because I just don't like taking drugs. But I finally caved and started Skyrizi. For me, the really noticeable effects started with the second shot. For the first time since I was 3 years old, my scalp is totally clear of plaques. My elbows, knees, and torso are totally clear. I have a random spot here and there, but that's it. Skyrizi has been great for my psoriasis, but also great for my mental health -- I no longer worry about plaques all over my body."

• J J...
• Taken for 1 to 6 months
• February 11, 2022

"I have plaque psoriasis, and I have tried the pills, but nothing has worked like Skyrizi. I have only had my second dose. My scalp and skin look great, the redness and flakes. Not a lot of side effects. I even had Covid just before my second dose. Everything went well. I am so glad my doctor started me on this medicine."

• Gre...
• Taken for 1 to 6 months
• November 21, 2022

"WOW!!! I have been suffering from psoriasis ever since my first Moderna COVID jab in May 2021. I broke out head to toe in red, itchy circles, and my scalp was the WORST! My scalp was shedding dandruff everywhere. I saw four different dermatologists, and I got many topical treatments, and I tried every OTC and holistic treatment, but within four days of my first dose of Skyrizi in August 2022, my psoriasis cleared up - 100%. ONE HUNDRED PERCENT. Zero side effects. I’m on my third dose, and I’m still 100% clear and I have zero side effects. I am so over the moon happy with this medication. I can finally sleep well at night because I’m not itching. I can finally wear black again. I got my life back. It took a lot of effort on my part to get a dermatologist to finally prescribe me it, but it’s soooooo worth it!"

• Pac...
• Taken for 2 to 5 years
• August 4, 2023

"In two months, the plaques were no longer spreading and stopped itching. After 6 months, they were fading, and after 2 years, I have perhaps 1 dime-sized eruption every few months. I can wear shorts again!"

• ASG...
• Taken for 1 to 6 months
• September 5, 2024

"At the age of 70 years old, I developed psoriasis. A few months later, I was in full-blown plaque psoriasis everywhere on my body. I had an emergency visit from my skin doctor. She recommended I try Skyrizi. By the second dose, almost all my plaque psoriasis had disappeared. I cannot express how happy I am. I highly recommend it to anyone who may be suffering from plaque psoriasis. It has also helped a lot with my joint pain."

• Fer...
• Taken for 6 months to 1 year
• October 16, 2023

"Overall, I have had a rather good experience with Skyrizi. Unfortunately, I have experienced a lot of itching, not of a dangerous nature, but the psoriasis, for which I take the medication, has been pretty much cured. I have, however, had a raving appetite on this and I have also begun to suffer hair loss (hair is coming out in handfuls and has gone VERY thin). On the whole though, my experience has been okay."

• Pap...
• Taken for 1 to 2 years
• August 21, 2021

"Worked great, but I had to stop taking due to upper respiratory infections. Before taking this, I never got an upper infection. My first injection, I wound up in the hospital with sepsis, double pneumonia incubated 3 days. I tried taking for a year but had to stop. Worked great."

• Ke ...
• Taken for 1 to 6 months
• November 27, 2022

"To get started, I spent $3,300 to begin my initial dose of Skyrizi. After which, I used Abbie Assistance for my following two doses (every 2 months). So far, it's controlling my plaque psoriasis quite well, but why is it $21,000 for its retail cost (per injection)? It's quite ridiculous! We find it excessively expensive, and I'm a 100% disabled veteran. The VA will only pay for a medicated tape, which is useless in trying to control plaque psoriasis all over the body!"

• Mon...
• Taken for 2 to 5 years
• March 5, 2025

"Skyrizi keeps my 'P' in check. It is wonderful to only inject once every 12 weeks. I think it's important to share our side effects as well. I suddenly developed neuropathy in my toes after starting Skyrizi. It occurs only when I walk and gets progressively worse the longer I walk. As soon as I sit down, the numbness goes away. I have to weigh this permanent disability of not being able to walk like I used to with clear skin. I'll take the clear skin."

• tha...
• Taken for 1 to 6 months
• April 26, 2024

"Wonder drug for me so far, been on it for about 3 months all active patches gone. Was extremely hesitant to touch systemics to the point my skin was horrendous. Only hyperpigmentation left behind now, hopefully that clears soon and the effects last. Haven't been ill, haven't had a single noticeable side effect."

• Hel...
• Taken for 1 to 6 months
• March 26, 2024

"I have currently taken three shots of Skyrizi prior to taking Skyrizi. I was on acitretin for about a year, to me, it seemed to have dried out all of my body parts, and at 41 years old, I was scared that I was basically ruined for the rest of my life. The dermatologist introduced me to Skyrizi as it helped my life tremendously."

• Imp...
• Taken for 1 to 6 months
• April 4, 2024

"I was about 40% covered with plaque. My onset occurred in 2018, and just kept taking new territory. I tried every topical OTC concoction that came to my attention. When I finally talked to a dermatologist, I was hopeful when she said she wanted to prescribe a biologic that I had already developed a good impression of, Skyrizi. I took the first of two introductory doses a few days before Christmas. By New Year's Day, I already noticed a slight lessening in the continuous sloughing off of dead skin. By the time I took the second intro dose near the end of January, I noticed a definite improvement in all my symptoms. The scales stopped falling altogether, and the itch was mostly gone. I had my 12th week injection recently, and my results have been completely astonishing! I was hoping so much that this would work, and it did! Finally, my suffering is behind me. I've had no side effects that I can definitely associate with this medication. Some mucous overproduction, but who knows?"

• 071...
• Taken for 2 to 5 years
• September 12, 2024

"After being covered by psoriasis head to toe and trying all kinds of PO treatments and laser therapy, etc., my dermatologist finally told me about Skyrizi, a biologic that I would have to inject every 3 months. Within 2 weeks of my first injection, I was 100% free of psoriasis. Till today (9/12/24), I'm still in remission! I have been using this biologic for 4 years, and I couldn't be happier. I honestly sometimes forget I have this autoimmune disease. The only side effect that could or could not be linked to this medication is my immunity when it comes to COVID. My body's ability to fight this respiratory infection struggles, and I wonder if it's due to taking Skyrizi. My doctor just orders antivirals when I do test positive for Covid, and I recover really quickly that way. I 10000% would recommend Skyrizi if you are struggling with psoriasis. Don't give up, give this medication a try! Seriously."

• Jod...
• Taken for 1 to 2 years
• December 13, 2024

"I had a diagnosis of plaque psoriasis that nothing seemed to help, that my dermatologist gave me, so they decided to try SKYRIZI. Three weeks after my first injection, I ended up with joint pain in my hands, ankles, knees, and neck. After my second injection shortly thereafter, my itching on my scalp and around my ears started to go away, shortly thereafter, all my joint pain went away. I’ve been on SKYRIZI for this entire year, and I have been cleared of all my scalp psoriasis in and out of my ears, and my joint pain is gone. I self-inject in the privacy of my home, which is very simple and easy to do, but I must thank AbbVie from the bottom of my heart because you really gave me my life back. Thank you again."

• Ama...
• Taken for 1 to 6 months
• May 28, 2024

"I was taking Humira. However, it was not working as well as it had been, so my doctor switched me over to Skyrizi. I just did start my Skyrizi; so far, it has been different from the Humira in that it is a larger dosage, but otherwise, it has not worked for me as quickly as the Humira did. Unfortunately, I have still had worsening psoriatic arthritis pain."

• Den...
• Taken for 1 to 2 years
• April 9, 2025

"This has been a godsend for my husband, who developed type 2 diabetes, and with it came plaque psoriasis from head to foot. It affected his self-esteem, stopped him from going out socializing, and he started to become depressed. Our doctor sent him to James Cook Hospital in Middlesbrough in the UK to see a dermatologist, who, after countless creams, light treatments, and tablets, offered him Skyrizi. It has cleared his psoriasis up completely. He has been on it a year now, and the change in his mental health is phenomenal. He has it every 3 months, 4 times a year. The only side effect is that 2 days after he has had the injection, he gets flu-like symptoms, which clear up within a week. So, if you get the chance, Skyrizi is the answer, it’s a game changer."

• Lif...
• Taken for 2 to 5 years
• April 18, 2025

"Skyrizi has changed my life. I was 80 percent covered in psoriasis. I had tried everything. I had flakes everywhere. Even on my hands and my face. I was depressed beyond belief. All my free time went into researching how to stop psoriasis. Nothing worked. Until Skyrizi. I am 100 percent clear today. And I haven't thought about my flakes in years."

• Hun...
• Taken for 1 to 6 months
• April 5, 2022

"My primary care physician informed me that Skyrizi caused me an upper respiratory infection and a bacterial skin infection. I've recovered now, but my doctor advised me to discontinue use, and I did."

• Rnr...
• March 25, 2023

"Had three doses and seems like my psoriasis has become worse. For a retail price of $20K per shot, I was expecting more than this."

• Dav...
• May 8, 2023

"I can't believe what they're charging for medications nowadays: $30,000 four times a year. Just ridiculous, out of control."

• She...
• Taken for less than 1 month
• March 8, 2025

"I took my first dose 8 days ago, and except for 3 small spots, I’m just about clear. Didn’t expect such drastic results so fast."

• jim...
• Taken for 6 months to 1 year
• December 1, 2023

"I have suffered from psoriasis for years before being prescribed Skyrizi. I have been on it for just under a year and am completely cleared except for dark areas. The itch and scaling is gone."

• Kri...
• Taken for 2 to 5 years
• December 16, 2023

"Skyrizi has been my wonder drug. I have tried so many others with little to no success. This was a game changer."